Biography
Margarida de Mello Aires, Brazilian physiologist (São Paulo 30 November 1935 – São Paulo 04 April 2019)
Pioneer in studies of the evaluation of hormonal mechanisms involved in the regulation of the acid base balance and extracellular volume of the organism, with numerous fundamental scientific works
Showed that the organism maintains the extracellular volume at the expense of pH
Pointed out the pCO2 balance in kidney
Showed how aldosterone acts on proximal tubule cells
Showed how arginine vasopressin acts on Na+/H+ exchanger via V2 luminal receptor and it is inhibited by peritubular v1 receptor
Authored Fisiologia (1991), a textbook about physiology used abroad too