Hsiang-fu Kung, Chinese molecular geneticist (04 September 1942 – 17 June 2019)

Developed the first human interferon of world market (Hoffmann La Roche Inc.)

First to purify and crystallize recombinant human leukocyte interferon α A

First to prove the transforming activity of Ras protein and establish the roleof phospholipase C and nerve growth factor in Ras-mediated signal transduction pathways

Developed anti-cancer drug targeting on the activity of Ras farnesyl-protein transferase

Demonstrated the physiological roles of bone morphogenetic protein-4 (BMP-4) during embryonic development in Xenopus embryo

Elucidated the BMP4 signaling pathways and demonstrated the role of GATA-1 b protein in the inhibition of neurogenesis

Purified several anti-tumor and anti-viral agents from TCM and elucidated their mechanisms of action that were patented

Identified the active anti-HIV components in HCG preparations

Held many patents in United States of America

LINKS

https://www.lihs.cuhk.edu.hk/en-us/research/investigators/kunghsiangfu.aspx