Andrés Oscar Manuel Stoppani Bahia, Argentine biochemist (Buenos Aires 19 August 1915 – Buenos Aires 18 March 2003)

Authored about 400 papers

ACHIEVEMENTS  

Demonstrated the existence of a physiological control on melanotrophic hormone secretion in Amphibia

Estudios fisiologicos y farmacologicos sobre los melanoforos de los batracios. Doctoral Thesis, Universidad de Buenos Aires (1942)

Reported the essential role of thiol groups  on catalytic activity of certain enzymes  

With R. Vallejos, C. Brignone, J. Brignone & A. Boveris described the regulatory actions of insulin and steroidal hormones on mitochondria functions 

With E. Ramos & J. Boiso clarified the transport of amino acids in yeasts and Trypanosoma cruzi

Described mitochondrial respiratory chain of Trypanosoma cruzi and its antioxidants enzymes deficiency

With Vidal discovered isozyme inhibition due to a peptide present in the same venom

Performed important contributions to knowledge of mitochondrial respiration mechanisms in mammalian organs

Performed contributions about biochemical mechanisms in chemotherapy using orthoquinones for treatment of Chagas disease and cancer

Important works on metabolic biochemistry, genetics and immunology of Trypanosoma cruzi

HONORS  

Member, Nobel Committee of Chemistry, Royal Swedish Academy of Sciences (2002)

President, Section of Hormonal Regulation of Enzymatic Processes, VI International Congress of Biochemistry, New York (1964)

Houssay Prize, OAS (1989)

BIBLIOGRAPHY

Saber y Tiempo 4(15):150-7, 2003