J.H. Robinson
J.H. Robinson, Barbados paleontologist and phycologist (fl. 1934-41) SOME BIBLIOGRAPHY The occurrence and distribution of the diatoms in the oceanic beds of Barbados. J. Barbados Mus. Hist. Soc. 3(3):149-52, 1936 The study of the organic remains in the oceanic beds of Barbados with special reference to the diatoms. J. Barbados Mus. Hist. Soc, 1(2):80-4, 1934 Some recente marine diatoms of Barbados HONORS Robinsonetta Hanna & Brigger 1964 (Fossil Diatoms)
Isaías Raw
Isaías Raw, Jewish Brazilian biochemist (São Paulo 26 March 1927- São Paulo 14 December 2022) ACHIEVEMENTS First demonstrated the possibility of sub mitochondrial fractions to catalyze oxidative phosphorylation Showed the presence of b5 and P450 cytochromes on mitochondrial outer membrane Established the role of b5 cytochrome in methemoglobin With N. Petragnani & O.C. Nogueira. Methaemoglobin reduction through cytochrome b5. Nature 184:1651, 1959 Demonstrated the presence of messenger RNA in nucleolus With R. Brentani & M. Brentani. Role of nucleolar ribonucleic acid in incorporation of ribosomal amino acid. Nature 201:1130, 1964 With T. Lau, B.J. Schmidt & A. Piva. Pain insensitivity, a new metabolic disease. Lancet 1:598-9, 1977 Claimed that is possible to produce human albumin from placenta (1989) Obtained a new less reactive cell pertussis vaccine and a new adjuvant in an integrated process OBTAINED NEW COMPOUNDS Isolated crotonase, an enzyme of oxidation cycle of fatty acids With J.R. Stern & Del Campillo. Enzymes of fatty acid metabolism. I. General introduction. Crystalline crotonase. J. Biol. Chem. 218:971, 1956 Discovered a new cytochrome Isolation of a cytochrome of the antimycin A sensitive pathway for DPNH oxidation. Experientia (1956) With O.C. Nogueira & J.B. Mallet Filho. Isolation of a DPNH-diaphorase from pig liver mitochondria. Enzymology 23:123-8, 1961 With J.C. Costa Maia, J. Pudles & B.J. Schmidt. Isolation of a new urine metabolite excreted in generalized congenital analgesia. Clin. Chimica Acta 54:225-34, 1974 PAPERS IN FAMOUS REVIEWS The inhibitory action of hydroxylamine on biological oxidations. Science 118:159, 1953 With W. Colli. Crystalline cytochrome b5. Nature 184:1798-1823, 1959 With R. Brentaini & M. Brentaini. Messenger activity of purified RNA from rat liver nuclei. Nature 214 (5093):1122-3, 1967 METHODS With N.M. Frazatti-Gallina, R.M. Mourão-Fuches, R.L. Paoli, H.G. Higashi et al. Vero cell rabies vaccine produced using serum-free medium. Vaccine 23(4):511-7, 2004 With A. Cianciarullo, E. Leme, W. Beçak & F.S. Kubrusly. Ultrastructural chemical reaction to detect saturated phospholipids of a natural lung surfactant. Biotechn. Letters 23:1202-6, 2001 With S. Grellet, E.A. Martins, V.M. Gonçalves, A.P. Lopes & J. Cabrera Crespo. An associated process for the purification of immunoglobulin F, catalase, superoxide dismutase and albumin from haemolyzed human placental blood. Biotechn. Appl. Biochem. 34:135-42, 2001 With J. Cabrera Crespo, V.M. Gonçalves, E.A. Martins, S. Grellet & A.P. Lopes. Albumin purification from human placenta. Biotechnol. Appl. Biochem. 31(2):101-6, 2000 With R. Sato, Q. Quintilio et al. Alternative method to determinate microquantitation of protein with low chromophobic content. Biochem. Technology 11:617-20, 1997 An improved process for Neisseria meningitidis serogroup C vaccine production. XXVI Reunião Anual Soc. Bras. Bioquím, 1997 A simple method to avoid bovine IgG contamination in monoclonal antibodies production. XXVI Reunião Anual Soc. Bras. Bioquím, 1997 An improved method for meningococcus C polysaccharide prufication. 10th Neisseria Congress, Baltimore, 1996 Development of an industrial method for catalase purification from human placenta. XXIV Reunião Anual Soc. Bras. Bioquím, 1995 A simple method for large scale purification of tetanus toxin. XXIV Reunião Anual Soc. Bras. Bioquím, 1995 Procedures for scaling up the recombinant 18kD hsp lepra protein production. Biotechn. Letters 9:527-32, 1995 With Y.M. Batarello, J. Cabrera Crespo, P.L. Ho & A. Carvalho. Purification of superoxide dismutase from placental haemolisate blood: a simple and efficient method. Biochem. Mol. Biol. Intern. 30:45-51, 1993 With B.J. Schmidt. Isocitric dehydrogenase in the serum as test of hepatic function. Rev. Paul. Med. 57:340-4, 1960 PATENTS (many of them methods and processes involved in vaccine and serum production) With Hisako G. Higashi. A test for Vibrio cholerae (1993) With S.M. Lucas, B. Becerril-Luján, M. Corona-Villegas, F.I. Coronas Valderrama, F. Zamudio Zuniga, E.S. Calderón Arana, P. L. Fletcher Jr, B.M. Martin & L.D. Possani. Produção de peptídeos de escorpiões Tityus serrulatus, Tityus bahiensis e Tityus stigmurus, e respectiva utilização dos mesmos na imunização de cavalos, visando a obtenção de soros anti-escorpionicos PI9505982-2 A2 (1995) With W.O. Dias, D.S.P.Q. Horton & C. Liberman. Desenvolvimento de vacina acelular anti-coqueluche pore tapa única de purificação de sobrenadante ou filtrado de cultura de Bordetella pertussis. PI9601748-1 A2 (1996) With M.M. Tanizaki & J. Cabrera Crespo. Uso de ultrafiltração tangencial para a eliminação de lipopolissacarídeo durante o processo de purificação de polissacarídeo capsular de bactérias Gram negativas. PI9601749-0 A2 (1996) With S. Lima Netto, F.S. Kubrusly, P.S. Araújo & R. Guidolin. Processo de obtenção de surfactante pulmonar natural exógeno de origem suína e produto resultante PI9900436-4 A2 (1999) With A.M. Moro. Processo de purificação de eritropoietina PI9900437-2 A2 (1999) With L.O. Fukasawa, R.P.F. Schenkman, M.M. Tanizaki & M.C. O. Gorla. Vacina bivalente conjugada contra meningite tipos “b” e “c”, e respectivo processo de obtenção PI0004568-3 A2 (2000) With M.A. Sakauchi, W. Quintilio, N. Furuyama, D.S.P.Q. Horton & W.O. Dias. Processo de obtenção de vacina pertussis acelular PI 0202458-6 A2 (2002) With C.R.R. Ramos, P.L. Ho, A.J. Simpson, N. Katz & M. Tendler. Antígenos derivados de helmintos com capacidade de conferir proteção contra parasitos PI0303266-3 A2 (2003) With I.C. de Almeida & L.R. Raja Gabaglia Travassos. Processos de obtenção do lipossacarídeo de Bordetella pertussis e de obtenção e preparação do lipídio a monofosforilado de Bordetella pertussis, uso do lipídio a monofosforilado de Bordetella pertussis e vacinas PI 0303416-0 A2 (2003) With F.S. Kubrusly, W.O. Dias, M.I. Esteves, N. Furuyama, D.S.P.Q. Horton, E. Leme, W. Quintilio, M.A. Sakauchi, S.M.A. Prado, E. Mendes & H.G. Higashi. Processo de obtenção de nova vacina pertussis celular. PI0402630-6 B1 (2004) With M.Takagi, M.M. Tanizaki & A.P.A.A. Lorthiois. Método de obtenção de um conjugado polissacarídeo capsular e proteína que resulta num composto covalente polissacarídeo-proteína para utilização como antígeno vacinal PI 0402984-4 B1 (2004) With M.Takagi, M.M. Tanizaki, J. Cabrera Crespo & V.M. Gonçalves. Processo de purificação de polissacarídeo capsular de microorganismos patogênicos para produção de vacina PI 0403855-0 A2 (2004) With F.S. Kubrusly, D. Iourtov, M.A. Sakauchi, F. L. dos Santos, S.C. Dias, E. Darini, N. Furuyama, S.M. A. Prado & H. G. Higashi. Metodo para obter lipídeo a monofosforilado da Bordetella pertussis como um subproduto da vacina celular contra coqueluche PI0721393-0 A2 (2007) With G.C. Barazzone, C.T. Perciani & M.M. Tanizaki. Método de conjugação de polissacarídeo capsular a uma proteína carregadora, para uso como antígeno vacinal contra bactérias encapsuladas, utilizando o reagente cloreto de 4-(4,6dimetoxi-1,3,5-triazin-2-il)-4-metilmorfolino (dmt-mm)
Ignacio Rodríguez Iturbe
Ignacio Rodríguez Iturbe, US / Venezuelan hydraulic engineer (Caracas 08 March 1942 – 28 September 2022) Internationally respected as expert on hydraulic climatology Recognized as the foremost surface water hydrologist in the world Described tridimensional fundamental structure of hydrographic cuencas and the mechanisms that give rise of them Formulated one of the first self-similar models to simulate extreme behavior Introduced Bayesian approaches to estimate parameters of stream flow simulating models and to select models of extremes Developed the Geomorphological Instantaneous Unit Hydrograph (GIUH) to quantify the discharge of a basin as function of basin geometry and rainfall First to provide a sound theoretical basis for sampling the rainfall process in space and time Showed that organization of the basin and resulting landscape patterns are not the result of randomness but process-driven phenomena that can be quantified in terms of well-defined principles Superheaded the use of point processes and fields to represent precipitation in space and time Showed that simple nonlinearities in the land-atmosphere dynamics have on patterns of hydrologic variables (i.e. soil moisture) First to connect the geomorphologic structure of the river basin to its hydrologic response with the theory of geomorphologic unit hydrograph With A. Rinaldo defined optimal channel networks and First to establish the connection between optimality and fractal growth (1997) First to provide a sound theoretical basis for the way drainage basins and their networks are arranged (1997) Developed a simple model for predicting the biodiversity of fish in river networks (2008) Developed methods to quantify the accuracy and value of hydrologic data Introduced Bayesian approaches to improve different models for river flows and to predict the likelihood of extreme hydrological events Showed that nature transports water and sediment out of the watershed in the most energy efficient way possible Established equations that yielded the drainage pattern that nature will produce under different climatic and geologic conditions Formulated the mathematical representation of rainfall as random, active point processes Defined the concept of ecohydrology Authored 4 papers in Nature and 23 in Proceedings of National Academy of Sciences USA LINKS https://www.princeton.edu/cee/people/data/i/irodrigu/Bio.pdf https://www.princeton.edu/cee/people/data/i/irodrigu/CV.pdf
Hugo Roberts Fernandez
Hugo Roberts Fernandez, Cuban sanitarist and military physician (Trinidad, Las Villas Province 20 July 1868 – La Habana 05 June 1948) Patented a thermos regulator (1925) Invented a device to generate and inject hydrocyanic acid into antrum of the rats (Golden Medal in San Francisco World Fair, 1915)
Hilton Rocha
Hilton Ribeiro da Rocha, Brazilian ophthalmologist (Cambuquira, Minas Gerais State 23 December 1911 – Belo Horizonte 23 May 1993) Authored over 100 papers ACHIEVEMENTS Improved surgical technique for catarata with intraocular lens implant Developed an immune therapy for retinitis pigmentosa Discovered a method of viewing the angle of the anterior chamber With L.J. Antunes, L.E. Ferreira & J.A. Nogueira Machado. Lymphocytes and glucocorticosteroids in vitro: a new auxiliary technique for identification of open angle glaucoma. Metabolic Ophthal. 2:15-17, 1978 SOME BIBLIOGRAPHY O ângulo da câmara anterior. Thesis (1942) With J. Alves Garcia. Ophtalmoplegia externa bilateral congênita familial. Brasil Med. 4:4, 1937 Roentgen examination in ophthalmology. Ophthalmos 1:62-78, 1939 With P. Elejalde. Em torno da classificação dos gliomas da retina. Ophthalmos 2:294-307, 1941 Molluscum contagioso. Ophthalmos 2, 1943 With E. Coscarelli. Lenticone anterior. Ophthalmos 2:219-26, 1943 Cromomicose conjuntival primitiva. Ophthalmos 3(2):205-18, 1943 Hipoplasia do nervo óptico. Arq. Bras. Oftalm. 8:1-9, 1945 With R. Soares. Conjuntivite lenhosa. Rev.Bras. Oftalm. 14(1):17-36, 1955 Ya-til une ophtalmie sympatique sans perforation? Bull. Mem. Soc. Franc. Ophtal, 1959 With J.M. Queiroz. Ensaios de hetero-transplante lamellar e desidratação da córnea pelo cloreto de sódio. Arq. Inst. Penido Burnier 18, 1961 With P.G. Galvão. Caso de cisticerco subretiniano juxta-papilar tratado pela fotocoagulação. Rev. Bras. Oftal. 22:41-49, 1963 With P. G. Galvão. Contribution a la thérapeutique du cysticerque intraoculaire. Bull. Mem. Soc. Franc. d’Opht 79:401, 1966 With P.G. Galvão. Immunological aspects of corneal heterografts. Int. Ophthal. Clin. 6:19, 1966 Some aspects of cryo-ophthalmology. Akt. Ophthal. Probl. 65:126-46, 1974 Der transferfaktor in der Ophthalmologie. Klin. Monatsbl. Augenheild 171:63-70, 1977 With L.J. Antunes. Primary retinitis pigmentosa: Autoimmunity? Metab. Ophthalmol 1:153-6, 1977 With P. G. Galvão , L.J. Antunes & J. Boteon. Imunologia e córnea. Anais Oftalm. 1(1):47-80, 1982 Patologia do segmento posterior como causa de deficiência visual na infância. Anais Oftalm. 2(1):92-5, 1983 Progressos e tendências no tratamento dos tumores intraoculares. Anais Oftalm. 3(1):43-53, 1984 AgS. Uveites e retinose pigmentar. Arqu. Bras. Oftalm. 50(2):94-9, 1987 HONORS Chevalier d’ Honner, Santé Publique de France Cavara Medal, Univ. Eye Clinic, Rome
Hilario Roxas
Hilario Atanacio Roxas, Philippine marine zoologist (Mariquina, Rizal 29 October 1896 – ?) DESCRIBED MARINE SPECIES Fish Taenioides caniscapulus 1938 with Ablan Ciliate Protozoa Metacylis kofoidi 1940 Rhabdonella fenestrata 1940 Tintinnidium ampullarium 1941 Tintinnopsis bacoorensis 1940 Tintinnopsis manilensis 1941 Cnidaria Anthelia elongata 1933 Anthelia molenderi 1933 Anthelia palawanense 1933 Capnella sabangensis 1933 Cespitularia hypotentaculata 1933 Cespitularia quadriserta 1933 Dendronephthya griffini 1933 Dendronephthya guggenheimi 1933 Dendronephthya malaya 1933 Dendronephthya manyanensis 1933 Dendronephthya moseri 1933 Heteroxenia lighti 1933 Heteroxenia medioensis 1933 Heteroxenia mindorensis 1933 Heteroxenia minuta 1933 Heteroxenia palmae 1933 Heteroxenia philippinensis 1933 Heteroxenia pinnata 1933 Lemnalia bantayensis 1933 Lemnalia bournei 1933 Lemnalia faustinoi 1933 Lemnalia grandispina 1933 Lemnalia scasa 1933 Lemnalia zimmeri 1933 Litophyton lighti 1933 Litophyton orientale 1933 Sansibia boquetei 1933 Sarcophyton moseri 1933 Sarcophyton tersum 1932 Stereonephthya campanulata 1933 Xenia amparoi 1933 Xenia cylindrica 1933 Xenia delicata 1933 Xenia felicianoi 1933 Xenia fisheri 1933 Xenia flava 1933 Xenia intermedia 1933 Xenia kukenthali 1933 Xenia lilieae 1933 Xenia mayi 1933 Xenia puertogalerae 1933 Xenia schenki 1933 Xenia tripartita 1933