Bernardo Leo Wajchenberg, Jewish Brazilian diabetologist and endocrinologist (São Paulo 06 April 1926 – São Paulo 21 August 2017)

From Polish father and Ukrainian mother

Authored over 200 books and 2 books

Showed the presence of brain embolism in patients with chronic Chagas disease 

With I. Nussenzveig, A. Spina-França, R. Macruz, J. Timoner & L.G. Serra Azul. Acidentes vasculares cerebrais embólicos na cardiopatia chagásica crônica. Arq. Neuropsiqu. 11:386-402, 1953 

With R.B. Radominski, P.G. Strassman & A. Halpern. Ultrasound as a new method of evaluation of body fat distribution. Intern. J. Obesity 19(2):22, 1995

IMPORTANT PAPERS

Beta-cell failure in diabetes and preservation by clinical treatment. Endocrine Reviews 28:187-218, 2007

Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocrine Reviews 21:697-738, 2000

With E.R. Quintão, B. Liberman & A.B.U. Cintra. Antagonism between adrenal steroids and parathyroid hormone. J. Clin. Endocrin. Metab. 25(12):1677-81, 1965

With S.S. Fajans, L.H. Louis, A.R. Hennes, R.D. Johnson et al. Metabolic effects of sulfonylureas in normal men and in various types of diabetic patients. Annals New York Acad. Sciences 71(1):207-14, 1957

Papers in renowned magazines

With G. Hoxter & R. Mungioli. Analysis of electrophoretic proteins. Nature 179:423-4, 1957

With G. Hoxter, E.H. Mello & A.B. Ulhoa Cintra. Non-esterified and esterified fatty acids in hepatocellular disease. Lancet 1:1218, 1960 

DESCRIBED NEW SYNDROMES AND OTHERS

With A.R. Hennes & A.B. Ulhoa Cintra. A syndrome characterized by hypothyroidism and galactorrhea. Port. Med. 44:693-702, 1960 (syndrome of amenorrhoea, galactorrhoea and primary hypothyroidism)

With F.J. Modesto, C. Ventrella, S.D. Giannini, B. Liberman & G. Hoxter. Lipoatrophic diabetes: a new variant characterized by tapeto-retinal degeneration, late onset, generalized lipoatrophy, insulin-resistant hyperglycemia and hyperlipidemia. Israel J. Med. Sciences 8(6):793, 1972 

With D.A. Malerbi, M.S. Rocha, A.C. Lerario & A.T. Santomauro. Syndrome X: a syndrome of insulin resistance. Epidemiological and clinical evidence. Diabetes Metab. Rev. 10(1):19-29, 1994

With A.C. Latronico, J. Anasti, I.J. Arnhold et al. A novel mutation of the luteinizing hormone receptor gene causing male gonadotropin-independent precocious puberty. J. Clin. Endocrinol. Metab. 80(8):2490-4, 1995

With C.Y. Hayashiro, R.G. Gondo, C. Ferrari et al. Familial growth hormone deficiency with mutated GHRH receptor gene: clinical and hormonal findings in homozygous and heterozygous individuals from Itabaianinha. Eur. J. Endocrinol. 142((6):557-63, 2000 (clinical and hormonal characterization of this familial dwarfism)

METHODS

With D.S. Freire, S.A.C. Siqueira, M.C.N. Zerbini et al. Development and internal validation of an adrenal cortical carcinoma prognostic score for predicting the risk of metastasis and local recurrence. Clin. Endocrin. 79(4):468-75, 2013

With V.C. Borghi & M. Nascimento. Rapid purification of radiodinated glucagon with Sep-Pak R reversed phase cartridges (1989)

With V.C. Borghi, M. Nascimento & L.A. C. de Marco. A rapid method for purification of radiodinated glucagon (1989)

With M.B. Mathor. A simplified method for the calculation of unbound or free testosterone by equilibrium dyalisis of undiluted plasma. Clin. Chim. Acta 145(2):213-8, 1985

With V.C. Borghi & R.H. Albuquerque. Evaluation of a sensitive and specific radioimmunoassay for pancreatic glucagon in human plasma and its clinical application. Clin. Chim. Acta 136(1):39-48, 1984

With I. T. Toledo e Souza, H. Pinto & R.R. Pieroni. Heterogeneity of human plasma insulin: technics for separation of immunoreactive components and determination by radioimmunoassay. Rev. Hosp. Clin. Fac. Med. S. Paulo 33(3):136-48, 1978 

With O.Z. Higa, I.T. de Toledo e Souza, R.R. Pieroni & H. Pinto. Standardization of radioimmunoassay technique for determination of plasma insulin and growth hormone (1974)

With R.H. Albuquerque. A simple technique for separation of cortisol metabolites by thin-layer chromatography and its application for the measurement of cortisol secretion rate. Arq. Bras. Endocrin. Metab. 16(3):183-90, 1967

With R.R. Pieroni & G. Hoxter. Preliminary mathematical model for glucagon-induced hepatic glyconeogeneolysis in man. Metab. Clin. Exp. 10:585, 1961

With I. Martirani, G. Hoxter, A.B. Ulhoa Cintra & I. Marian. Determination of polyssacharide hexoses and hexosamines in normal human sera. J. Lab. Clin. Med. 54:773-8, 1959

HONOURS

Distinguished Physician Award, Endocrine Society (2007)