Parodi family
Armando Santiago Parodi Trabucco, Argentine microbiologist and parasitologist (Haedo, Buenos Aires Province 06 May 1909 – 23 June 1969) Isolated the Junín virus, causative agent of hemorrhagic Argentine fever With D.J. Greenway, H.R. Rugiero, M. Frigerio, J.M. de la Barrera, N. Nettler, F. Garzón, M. Boxaca, L.B. Guerrero & N.R. Nota. Sobre la etiologia del brote epidémico de Junin. El Dia Medico 30:2000-10, 1958 Studied the characteristics of Junín virus With C.E. Coto, M. Boxaca, S. Lajmanovich & S. Gonzalez. Characteristics of Junín virus. Arch. fur d. Ges. Virusforsch. 19(4):393-402, 1966 With M. Weissenbacher demonstrated that immune serum prevents death by Junín virus Developed an attenuated strain of Junín virus Isolated other causative agents Aislamiento del agente causal de un síndrome de encefalo-papilitis. Rev. Soc. Arg. Biol. 30:53, 1954 With N.E. Mettler & C.A. Gianantonio. Aislamiento del agente causal del sindrome uremico-hemolítico. Medicina 23:139, 1963 Performed works on immunity in Chagas disease HONORS Medicine & Physiology Nobel prize nominee His son, Armando José Antonio Parodi Lailame, biochemist (Buenos Aires 16 March 1942 – Showed that the dolichol P-dependent pathway of protein N-glycosylation was present in mammalian and yeast (1975-8) First description of the role of dolichol derivatives in the initial stages of protein N-glycosylation Unravelled a basic metabolic pathway leading to the formation of glycoproteins and polysaccharides in mammals, plants fungi and protozoa (1981-3) Showed that in members of the Trypanosomatidae family the pathway of N-linked oligosaccharide processing of protein is similar found that found in other eukaryotic cells With L.A. Quesada Allué & J.J. Cazzulo. Pathway of the protein glycosilation in the trypanosomatid Crithidia fasciculata. Proc. Nat. Acad. Sci. 78:6021-5, 1981 Established its occurrence in the endoplasmic reticulum (1984) Suggested the role of transient glycosylation in quality control og glycoprotein folding (2004-5) RELEVANT PAPERS With O.A. Castro & F. Movsichoff. Preferential transfer of the complete glycan is determined by the oligosaccharyltransferase complex and not by the catalytic subunit. Proceed. Nat. Acad. Sciences USA 103:14756-60, 2006 With N. Keith & J.J. Caramelo. Glycoprotein tertiary and quaternary structures are monitored by the same quality control mechanism. J. Biol. Chem. 280:18138-41, 2005 With J.J. Caramelo, O.A. Castro & G. Prat-Gay. The endoplasmic reticulum glucosyltransferase recognizes nerly native glycoprotein folding internmediates. J. Biol. Chem. 279:46280-5, 2004 With J.E. Ugalde & R.A. Ugalde. De novo synthesis of bacterial glycogen: Agrobacterium tumefaciens glycogen synthase is involved in glucan initiation and elongation. Proceed. Nat. Acad. Sciences USA 100:10659-63, 2003 With J.J. Caramelo, O.A. Castro, L.G. Alonso & G. Prat-Gay. UDP-Glc: glycoprotein glucosyltransferase recognizes structured and solvent accessible hydrophobic patches in molten-globule like folding intermediates. Proceed. Nat. Acad. Sciences USA 100:86-91, 2003 With C. Zuber, J.Y. Fan, B. Guhl, J.H. Fessler, C. Parker & J. Roth. Immunolocalization of UDP-Glc: glucoprotein glucosyltransferase indicates involvement of pre-Golgi intermediates in protein quality control. Proceed. Nat. Acad. Sciences USA 98:10710-5, 2001 With D.C. Tessier, D. Dignard, A. Zanpun, A. Radominska-Pandya, J.J.M. Bergeron & D.Y. Thomas. Cloning and characterization of mammalian UDP-glucose Glycoprotein Glycosyltransferase and the development of a specific substrate for the enzyme. Glycobiology 10:403-12, 2000 With M. Sousa. The molecular basis for the recognition of misfolded glycoproteins by the UDP-Glc: glycoprotein Glucosyltransferase. EMBO J. 14:4196-203, 1995 With V. Alvarez & R. Couso. Characterization of the mannose 6-phosphate dependent pathway of lysosomal enzyme routing in an invertebrate. Biochem. J. 310:589-95, 1995 With S. Merello & R.O. Couso. Characterization and partial purification of a novel enzymatic activity: UDP-GlcNAc Ser-protein N-acetylglucosamine-1-phosphotransferase from the cellular slime mold Dictyostelium discoideum. J. Biol. Chem. 270:7281-7, 1995 With S. Merello & M.T. Xavier. Novel Rhamnosyl and Ribosyl and uncommon (xylosyl) monosaccharide residues are present in asparagine-linked oligosaccharides of the trypanosomatid Blastocrithidia culicis. J. Biol. Chem. 269:20294-8, 1994 With S. Trombetta & M. Bosch. Glucosylation of glycoproteins by mammalian, plant, fungal and trypanosomatid protozoa microsomal membranes. Biochemistry 28:8108-16, 1989 With G.Z. Lederkremer. 3-0 methylation of mannose residues: a novel reaction in the processing of N-linked oligosaccharides occurring in Mucor rouxii. J. Biol. Chem. 259:12514-8, 1984 With D.H. Mendelzon & G.Z. Lederkremer. Transient glycosylation of protein-bound Man9GlcNAc2, Man8GlcNAc2 and Man7GlcNAc2 in calf thyroid cells: a possible recognition signal in the processing of glycoproteins. J. Biol. Chem. 258:8260-5, 1983 With L. Quesada Allué. Novel mannose carrier in the Trypanosomatid Crithidia fasciculata behaving as a short-saturated polyprenyl phosphate. Biochem. J. 212:123-8, 1983 With N.H. Behrens, L.F. Leloir & H. Carminatti. The role of polyprenyl-bound saccharides as intermediates in glycoprotein synthesis in liver. Proceed. Nat. Acad. Sciences USA 69:3268-72, 1972 With N.H. Behrens & L.F. Leloir. Glucose transfer from dolichol monophosphate glucose. The product formed with endogenous microsomal acceptor. Proceed. Nat. Acad. Sciences USA 68:2857-60, 1971 HONOURS International Research Scholar, Howard Hughes Medical Institute (1997-2011) Karl Meyer Award in Glycobiology, American Society for Glycobiology (2011)
Paris Pismis
Marie Paris Pismis de Recillas, Turkish-born Mexican astronomer (Ortaköy Village, Besiktas District, Istanbul 30 January 1911 – Ciudad de Mexico 01 August 1999) Nee Mari Sukiasyan of Armenian descent Authored over 120 papers Gained international recognition for her studies on ionized nebulae kinematics Carried out some of the first photometric observations of young stellar clusters Discovered the reason for the waves of spiral galaxies rotation curves based on different stellar populations (1960s) Explained the structure of spiral galaxies Demonstrated that period-luminosity relationship of RR Lyra variable stars in M3 was distinct from Cepheids stars (1940s) Suggested the existence of Mildly Active Galactic Nuclei Discovered 3 globular clusters and 23 open clusters Proposed an unified theory of central nuclear activity in galaxies
Oswald Otto Popper
Oswald Otto Popper, South African surgeon (28 March 1899 – Dunkeld, Johannesburg 14 August 1957) From Austrian parents Elaborated the transtympanic method of labyrinth fenestration without opening for the mastoid (1946) Designed surgical instruments such as a suction dissector, a bronchoscope with proximal lighting, a double-blade hemostatic guillotine and an adenotome PATENTS Means for the insertion of intra-vaginal packs US2416642A (1947) Vaginal pack device US2351836A (1944)
Orfilio Pelaez
Orfilio Orestes Pelaez Molina, Cuban ophthalmologist (Cespedes District, Camaguey Province 17 November 1923 – La Habana 17 January 2001) Developed a new surgical treatment of retinitis pigmentosa (1987) Described and named a scleral sign called tattoo sign
Olivério Pinto
Olivério Mário de Oliveira Pinto, Brazilian ornithologist (Jaú, São Paulo State 11 March 1896 –Piracicaba 13 June 1981) DESCRIBED NEW TAXA Aves Species Hylopezus nattereri 1937 Neopelma chrysolophum 1944 Synallaxis infuscata 1950 Subspecies Attila rufus hellmayri 1935 Campylorhamphus trochilirostris guttistriatus 1955 with Camargo Campylorhamphus trochilirostris omissus 1933 Cercomacra laeta sabinoi 1939 Chlorostilbon lucidus berlepschi 1938 Chordeiles pusillus saturatus 1957 with Camargo Cichlocolaptes leucophrus holti 1941 Conopophaga melanops nigrifrons 1954 Cranioleuca semicinerea goyana 1936 Cranioleuca vulpina solimonensis 1938 Cyanocorax chrysops insperatus 1961 with Camargo Deconychura longicauda zimmeri 1974 Dendrocincla fuliginosa taunayi 1939 Furnarius tricolor araguaiae 1952 with Camargo Glyphorhynchus spirurus paraensis 1974 Hylocharis chrysura lessoni 1955 Hypocnemis flavescens perflava 1966 Hypoedaleus guttatus leucogaster 1932 Momotus momota marcgravianus 1961 with Camargo Myiozetetes similis pallidiventris 1935 Myrmeciza ruficauda soror 1940 Neomorphus geoffroyi maximiliani 1962 Nyctiprogne leucopyga majuscula 1952 with Camargo Odontophorus gujanensis snethlagei 1938 Ortalis squamata remota 1960 Piaya cayana hellmayri 1938 Picumnus pygmaeus distinctus 1961 with Camargo Picumnus lafresnayi pusillis 1936 Picumnus limae saturatus 1961 with Camargo Pionus menstruus chlorocyanescens 1962 Pionus menstruus cyanescens 1960 Platyrinchus mystaceus niveigularis 1954 Pyriglena leuconota interposita 1947 Schiffornis turdina intermedia 1954 Schistochlamys ruficapillus sicki 1952 with Camargo Schoeniophylax phryganophilus petersi 1949 Selenidera gouldii baturitensis 1961 Sittasomus griseicapillus transitivus 1948 with Camargo Synallaxis brachyura jaraguana 1936 Tachornis squamata orientalis 1961 with Camargo Thamnophilus aethiops distans 1954 Trogon melanurus occidentalis 1950 Xenops minutus alagoanus 1954 Xiphocolaptes major remoratus 1945 Xiphocolaptes promeropirhynchus paraensis 1945 Xiphorhynchus eytoni gracilirostris 1957 with Camargo Mammalia Subspecies Sciurus (Guerlinguetus) aestuans garbei 1931 HONORS Oliverius Soares & Soares 1945 (Arachnida)
Nuno Alvares Pereira
Nuno Álvares Pereira, Brazilian pharmacologist (Rio de Janeiro 12 August 1920 – Rio de Janeiro 10 January 2012) Authored over 100 scientific works mainly on natural products pharmacology With H. Moussatché gave pioneering contributions to knowledge of corticotrophic hormones Proposed a method for dosage of heparin Notas sobre a padronização e ensaio da heparina. Rev. Bras. Farm. 11:423, 1953 Discovered alkaloid polyneuridine from Aspidosperma polyneuron With L. Antonaccio, B. Gilbert, C. Dejerassi et al. Polyneuridine, a new alkaloid from Aspidosperma polyneuron and some observations on mass spectra of indole alkaloids. J. Amer. Chem. Soc. 84 (2161): 70, 1962 With R.J. Siqueira Jaccoud first showed cardiotonic activity of Oxypetalum balansae (1979) Discovered alkaloid nitidine from Fagara tingoassuiba, that is able to inhibit reverse transcriptase (1990s) With W.B. Mors & C.T. Rizzini Medicinal Plants of Brazil with international circulation (2000) MEMBERSHIP Active Member, New York Academy of Sciences (1963) Member, American Society of Pharmacognosy (1970)