Helge Harboe
Helge Harboe, Danish-born Brazilian civil engineer (01 April 1891 – Rio de Janeiro 08 April 1977) Developed reinforced concrete tanks for a variety of fluids BRAZILIAN PATENTS With A.L. Montenegro, F.A.O. G. Zeemann & Weskott Co. one patent (1932) With F.A.O. G. Zeemann. Water-jacketed reinforced concrete tanks for mineral oils (nº 21.152) 1933 A new kind of reinforced concrete for fluids or other substances with side buoyancy (1933) A new way to build reinforced concrete and/or cement depots or tanks for mineral oils, petroleum, gasoline, benzine or other liquids like alcohol and alikes (1933)
Heinrich Hauptmann
Heinrich Friedrich Hauptmann, German-born Brazilian organic chemist (Breslau 10 March 1905 – São Paulo 21 July 1960) ACHIEVEMENTS Attained international fame due his studies about sulphur organic compounds Described and synthetized many new mercaptols to science Prepared oxalacetic acid semi-mercaptols (with Horst Berl) Prepared dicarboxilic mercapto-amino acids First to study reactions of keto-steroids with thiols (1947) Isolated many compounds from coffee and cashew oils, leafs of Cassia alata and carqueja Described with G.E.R. Schulze a new microvolumenometer With B. Wladislaw. Síntese de alguns novos tiobenzoatos e tioacetatos de alquila de cadeia comprida . Ciência e Cultura 5: 137-137, 1953. With Jandira França. Um simples microextractor. Anais Assoc. Quim. Brasil 2:126, 1943 With Cyro Marino. Novas reações de compostos orgânicos de enxofre com níquel de Raney. Rev. Bras. Quim 44(262):314, 1957
Gustavo Hoecker Salas
Gustavo Hoecker Salas, Chilean biologist (Rere, Biobío Province, VIII Region, December 05 December 1915 – 19 March 2008) Authored over 100 scientific papers Defined that H2 complex in chromosome 17 of mice was a genetic complex independent of Snell Postulated that isoantigens participate in the mechanism of recognition of foreigness Described a new tumor With D. Brncic. Nuevo sarcoma transmisible de la gallina. Rev. Sudam. Morfol. 7:56-74, 1949 SOME BIBLIOGRAPHY With D. Brncic & G. Gasic. Immunity in mice against leukemic cells of the same generic composition. Acta Unio. Internat. contre cancer, 7: 761–764, 1952 With A. Martínez, S. Markovic & O. Pizarro. Agitans, a mutation with neurological effects in the house mouse. Journal of Heredity, 45: 10–14, 1954 With S. Counce & P. Smith. The antigens determined by the H–2 locus: a rhesus–like system in the mouse. Proc. Natl. Acad. Sci., 40: 1040–1051, 1954 With N. Kaliss & F. Bryant. The effects of cortisone on isohemagglutinin production in mice. Journal of Immunology, 76: 83–88, 1956 Genetic Mechanisms in tissue transplantation in the mouse. Cold Spring Harbor Symp. on Quant. Biol., 21: 355–362, 1956. With O. Pizarro & A. Ramos. Some new antigens and hitocompatibility factors in the mouse. Transplantation Bull., 6: 407–411, 1959 With O. Pizarro, A. Ramos & P. Rubinstein. The distribution in the tissues and the development of H–2 antigens of the mouse. Proc. Natl. Acad. Sci. EE.UU., 47:1900–1907, 1961 With F. Morgado, A. Ramos & O. Pizarro. Genotypes and Bone Marrow Transplantation. In: Effects of Ionizing Radiation on Immune Processes. Edited by Ch. A. Leone. Gordon and Breach, New York, pp. 381–401, 1962 With G. D. Snell & J. Stimpfling. Evidence that the “R” and “Z” blood group specificities of mice are allelic and distinct from H–2. Transplantation 5: 3, 1967 With A. Ramos & A. Ferreira. Restrictions of antibody production against the H–2 complex. Transplantation Proceedings. 2: 7682, 1970 With A. Ferreira & C. Moreno. Lack of correlation between the effects of cortisone on mouse spleen plague forming cells and circulating anti–sheep red blood cell huemolysins. Immunology 24: 607, 1973 With F. Penalva da Silva, G.F. Hoecker, N.K. Day, K. Vienne & P. Rubinstein. Murine complement component 3: genetic variation and Linkage to H–2. Proc. Nat. Acad. Sci. 75: 963, 1978 With A. Ramos & F. Zavala. Immune response to glutara ldehyde treated cells. 1 Dissociation of immunological memory and antibody production. Immunology 36: 775, 1979 With P. Rubinstein & K. Vienne. The location of the C3 and GLO (Glyoxalase 1) loci of the IX th linkage group in mice. J. Immunology 122: 2584, 1979 With A. Ramos, M. A. Mordojovich & M. Gajardo. New H–2 linked cell and serum antigens. Exp. Clin. Immunogenet. 2: 198–205, 1985
Guofan Hong
Guofan Hong, Chinese molecular biologist (Ningbo, Zhejiang Province 24 December 1939 – Made notable contributions to nucleotide sequencing technology working under supervision of Nobel prize Frederick Sanger (1970s) Discovered that the diffusion of nucleic acids may be counteracted by electric force while moving in the gradient electric field (1978) A method for sequencing single-stranded cloned DNA in both directions. Biosc. Reports 1:243-52, 1981 Established heat stable Bst DNA sequencing system (1987) Improved the efficiency of nucleotide sequencing technology (1992) Proposed a molecular model based on gene nodD by which the nodulation genes in Rhizobia were regulated (1994) Designed a rapid and accurate BAC fingerprinting-anchoring strategy used in the construction of BAC-contig map of the rice genome (1997) Methods With S.H. Lee, S.C. Ge & S.X. Zhou. A novel low temperature PCR assured high-fidelity DNA amplification. Int. J. Mol. Sci. 14(6):12853-62, 2013 With S.T. Liu. Three minute G+A specific reaction for DNA sequencing. Anal. Biochem. 255(1):158-9, 1998 With Y.Y. Lu & F.D. Ni. Rapid method for identifying subclones bridging gaps between contiguous DNA sequences. Chin. J. Biotechnol. 5(3):157-60, 1989 A simple method for identification of gap-bridging subclones in DNA sequencing. Biosc. Reports 8(6):549-51, 1988 With M.D. Biggin & T.J. Gibson. Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination. Proc. Natl. Acad. Sci. USA 80(13):3963-5, 1983 A systemic DNA sequencing strategy. J. Mol. Biol. 158(3):539-49, 1982 Patents With Y.J. Yang & J. Zhu. Low-temperature cycle extension of DNA with high polymerization (priming) specification. CA2449560A1 (2002) JP2003503756A (2002) AU2002324272A1 20030087237 (2003) With W.H. Huang. DNA polymerase having ability to reduce innate selective discrimination against fluorescent dye-labeled dideoxynucleotides 6165765 (1998) 6845909 (2000) 6818431 (2000) USPTO 20050089910 (2004) With F. Zhai & W.H. Huang. A new DNA polymerase with proof-reading 3’-5’ exonuclease activity EP0810288A3 (1996) US08/642,684 (1996) JP8160402A (1996) With F. Zhai. New bst-DNA polymerase with proof-reading 3’-5’ exonuclease activity JPH09140376A (1995) With F. Zhai. Bst DNA polymerase with proof-reading 3’-5’ exonuclease activity / A DNA polymerase which is highly efficient and which can withstand high temperatures (HiFiBst) EP0712927 A2 (1995) CN94118990 (1994) LINKS www.hlhl.org.cn/english/showsub.asp?id=272
Gunter Hoxter
Gunter Hoxter, Brazilian pharmacist and engineer (1914 – 1999) DESCRIBED DISEASES With F.J. Modesto, C. Ventrella, S.D. Giannini, B.L. Wajchenberg & B. Liberman. Lipoatrophic diabetes: a new variant characterized by tapeto-retinal degeneration, late onset, generalized lipoatrophy, insulin-resistant hyperglycemia and hyperlipidemia. Israel J. Med. Sciences 8(6):793, 1972 Papers in renowned journals With B.L. Wajchenberg, E.H. Mello & A.B. Ulhoa Cintra. Non-esterified and esterified fatty acids in hepatocellular disease. The Lancet 1:1218, 1960 With A. Fajer & E. Fraga. Electrophoretic pattern of the soluble proteins of a pineal body extract. Nature 196:274, 1962 DEVELOPED METHODS With R. Mungioli. Electrophoretic studies. I. Methods and technique. Mem. Inst. Butantan 22:75-126, 1949 With B. L. Wajchenberg & R. Mungioli. Analysis of electrophoretic proteins. Nature 179:423-4, 1957 (a method for the evaluation of Tiselius electrophoretic patterns based on geometrical analysis) With I. Martirani, B.L. Wajchenberg, A.B. Ulhoa Cintra & I. Marian. Determination of polyssacharide hexoses and hexosamines in normal human sera. J. Lab. Clin. Med. 54:773-8, 1959 With R.R. Pieroni & B.L. Wajchenberg. Preliminary mathematical model for glucagon-induced hepatic glyconeogeneolysis in man. Metab. Clin. Exp. 10:585, 1961 With M. Jamra, J.I. Araújo & V. Maspes. The solubility test for abnormal hemoglobins: method, evaluation and significance in various hemoglobinopathies. Sangre 11:83-94, 1966 With M. Jamra & F. Ventura. Hemoglobin: determination using the cyanmethemoglobin method. Use of an artificial solution for the calibration of colorimetric instruments. Rev. Hosp. Clin. Fac. Med. 22 (Suppl.):303-4, 1967 With Or. Cesar O. Barretto. Glicoproteínas – método de coloração em eletroforese de papel. Rev. Hosp. Clinicas 26(1):23-4, 1971 Suggested isosbestic wavelength calibration in clinical analysis. Clin. Chem. 25(1):143-6, 1979
Guillermo Haro Barraza
Guillermo Haro Barraza, Mexican astronomer (Ciudad de Mexico 21 March 1913 – Ciudad de Mexico 25 April 1988) Authored over 80 papers and about 30 books ACHIEVEMENTS Discovered a great number of planetary nebulae toward galactic center (with Enrique Chavira & Braulio Iriarte), besides stellar aggregates of distinct ages, many T Tauri stars, 11 galactic novae, 1 extragalactic nova and 1 extragalactic super nova Discovered 103 new planetary nebulae (1952) With W. Morgan discovered flare stars in the Orion nebula (1953) Discovered new flare stars in the Pleiades (1970) Showed that some T-Tauri stars were flash stars With S. Torres & E. Chavira. A fluor-like new variable star in Orion. Infor. Bull. Variable Stars (1985) With W.J. Luyten discovered a large number of stars (1962) Discovered blue galaxies with emission lines spectrum know as Haro galaxies (1956) Established the relationship between a stellar aggregate age and spectral type of bursting stars With G.H.Herbig developed a trichromatic photograph technique using Schmidt camera for statistical study of galaxies (1955) Developed a method to study rapid stellar variability using Schmidt camera EPONYMY Haro planetary nebula Haro-Chavira comet (1954) Herbig-Haro objects Haro-Luyten blue stellar objects Palomar-Haro-Luyten objects MEMBERSHIP/HONORS Associate Member, Royal Astronomical Society, England (1959) being the first person from a developing country to be elected Vice-President, American Astronomical Society (1957-60) Doctor Honoris Causa, Case Western Reserve University, Cleveland (1953) Honor Medal, Armenian Academy of Sciences (1962) Lomonossov Gold Medal, USSR Academy of Sciences (1986)