Francisco Saturnino Rodrigues de Brito
Francisco Saturnino Rodrigues de Brito, Brazilian sanitary engineer (Campos, Rio de Janeiro State 14 July 1864 – Pelotas, Rio Grande do Sul State 10 March 1929) ACHIEVEMENTS Built innovative concrete bridges (1906-7) Developed a economic model of fluxible reservoir known as fluxible reservoir Saturnino de Brito (1900), used in Europe Continent Invented telehydrodynamics system for sewerage, presented in book Technologie Sanitaire Invented many devices used in water supply and sewerage systems, developing and introducing many improvements in sanitary apparatuses such as flexible siphon, radial junction, piece of radial conection, grease trap, self-ventilated siphons, between others Set up a system of districtal automatic electric raising for sewerage system in Santos (São Paulo State), the first of this kind in the world (1914) His sanitation technical processes were adopted in France, England and United States Although he was author of inventions, he didn’t patented any of them MEMBERSHIP Life Member, American society of Civil Engineers Life Member, Societé des Ingenieurs Civils de France Life Member, American Water Works Association
Francisco Bruno Lobo
Francisco Alipio Bruno Lobo, Brazilian histologist (22 February 1910 – 18 February 1988) Brother of virologist Manoel Bruno Lobo ACHIEVEMENTS Developed a new technique for impregnate nervous system (1937). Sobre uma nova técnica de impregnação do sistema nervoso. Patologia Geral 22:4-7, 1937. Developed a new reaction for premature diagnosis of pregnancy (1936). Ensaio sobre uma nova reação para o diagnóstico precoce de gravidez. Annaes Bras. Ginecol. 1:267-73, 1936. SOME BIBLIOGRAPHY With W. Berardinelli. Sobre os glomus de Masson. Communication to Medicine & Surgery Society of Rio de Janeiro. 12 December 1938. Os glomus neuro-vasculares do tegumento humano. Thesis. Rio de Janeiro, 1940. A célula de Rouget. Thesis. Rio de Janeiro, 1945. Associação fuso-espilar Amígdalas palatinas e infecções Pesquisas sobre a inervação da glândula tireóide Intersticial testicular Histofisiologia da tireoide Classificação dos vasos anastomóticos de acordo com a estrutura de suas paredes His brother, João Bruno Alipio Lobo, Brazilian morphologist and histochemist (Paris 26 October 1913 – Rio de Janeiro 18 January 1995) CONTRIBUTIONS Teste para o estrogênio. Brasil Med. LX(11-3): 85-6, 1946 With D. de Paola & A.C. Ferreira. Reação histoquímica para proteínas sulfuradas em colpocitologia (1952) SOME BIBLIOGRAPHY Nota prévia sobre as células endócrinas do rim do muçuan. Seara Med. 2:337-45, 1942 With W.B. Atkinson. Studies on the metrial gland in the mouse. Anat. Record. 94:521, 1946 Contribuição ao estudo da glândula metrial na camundonga albina. Thesis, Escola Nacional de Veterinária, Universidade Rural (1949) With D. de Paola. Variações de um tipo especial de basofilia em pâncreas de rato com diabetes aloxânico. Arq. Clin. 13:124, 1951 As glândulas do proventrículo da galinha (Gallus gallus). Alguns aspectos de sua anatomia microscópica. Anais Congr. Bras. Veter. 5:729-34, 1951 With P. de Góes. Glycoproteins in Negri bodies revealed by histochemical technique. Anais Microb. 2:43, 1952-3 With D. de Paola, W.A. Chagas & M.P.A. Leme. Some histochemical reactions in cells of the metrial gland in albino mouse. Veterinaria 8:22-8, 1953 With A. Mies Filho. Contribuição ao estudo histoquímico da pigmentação do útero de ovinos. Veterinaria 3:6-13, 1953 With A. Mies Filho. Hemorragia perimetrial. Veterinaria 8(4):4-6, 1954 With D. de Paola. Algumas reações histoquímicas em moela de galinha (Gallus domesticus). I. Pesquisas de compostos sulfurados. Folia Clin. Biol. With D. de Paola. Algumas reações histoquímicas em moela de galinha (Gallus domesticus). Pesquisas de polissacarídeos (1955) Contribuição ao estudo do citotrofoblasto da placenta humana. Thesis (1956) With W.A. Chagas & S.L. Oliveira e Silva. Alguns aspectos morfoestruturais do esôfago e do estômago do urubu (Coroagype atratus foetens). An. Col. Anat. Bras. 16:56-62, 1960 With W.A. Chagas & S.L. Oliveira e Silva. Aspectos histológicos da mucosa gástrica da Tilapia melanopleura Dum. (Actinopterygii, Cichlidae). An. Col. Anat. Bras. 16:105-14, 1960 With G.L. Santa Rosa. Aspectos da anespermatogênese provocada com injeções de espermatozoides. An. Col. Anat. Bras. (Separata) With W.M. Abreu & G.L. Santa Rosa. Immunological study of the testicle and epididymis of the guinea pig. Int. J. Fertil. 8:539-46, 1963 With W.M. Abreu & G.L. Santa Rosa. Propriedades antigênicas de contenido da vesícula seminal do cobaio. An. Anat. Brasil. 8:39, 1963 Aspecto histoimunológicos do aparelho genital masculino do cobaio e do coelho (1976)
Francisco Bolivar Zapata
Francisco Gonzalo Bolívar Zapata, Mexican molecular biologist and biotechnologist (Ciudad de Mexico 07 March 1948 – Great grandson of entomologist Ignacio Bolívar and grandson of Candido Bolívar Authored over 240 works (over 16,000 citations) Regarded as a world pioneer on genetic isolation, characterization and manipulation of micro-organisms Isolated, characterized and manipulated genes of basic and industrial purposes Under the guidance of Herbert Boyer, designed and developed pBR322 plasmid (the multipurpose cloning vehicle) worldwide used With H. Boyer et al. first to demonstrate that it was possible to express mammalian proteins (insulin and somatostatin) in bacteria using recombinant DNA technology (1977-9) Proposed genetic and physiological modification of microoraganisms in for better design and optimization of metabolites and proteins production (1990s) Developed technologies for human insulin production via pro insulin RELEVANT PAPERS With N. Floras, J. Xiao, A. Berry & F. Valle. Pathway enginering for the production of aromatic compounds in Escherichia coli. Nature Biotechn. 14(5):620-3, 1996 (pioneer work on genetical engineering of metabolic pathways) With D.V. Goeddel, D.G. Kleid, H.L. Heyneker, D.G. Yansura, R. Crea, T. Hirose, A. Kraszewski, K. Itakura & A.D. Riggs. Expression in Escherichia coli of chemically synthesized genes for human insulin. Proceed. Nat. Acad. Sciences USA 76:106-10, 1979 With K. Itakura, T. Hirose, R. Crea, A.D. Riggs, H.L. Heyneker, H.W. Boyer. Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostain. Science 198 (105663), 1977 With M.C. Betlach, H.L. Heyneker, J. Shine, R.L. Rodríguez & H.W. Boyer. Origin of replication of pBR345 plasmid DNA. Proceed. Nat. Acad. Sci. USA 74:5265-9, 1977 With R.L. Rodríguez, P.J. Greene, M.C. Betlach, H.L. Heyneker & H.W. Boyer. Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene 2:95-113, 1977 DEVELOPED With A. Sabido, L.M. Martínez, R. de Anda, A. Martínez & G. Gosset. An novel plasmid vector designed for chromosomal gene integration and expression: use for developing a genetically stable Escherichia coli melanin production strain. Plasmid 69:16-23, 2013 With A. Sabido, A. Martínez & G. Gosset. Generación de un sistema para la integración y expresión de genes en el cromosomo de Escherichia coli. Biotecnologia 15:35-49, 2011 With S. LeBorgne, B. Palmeros & G. Gosset. Improvement of the pBRINT-Ts plasmid family to obtain marker-free chromosomal insertion of cloned DNA in E. coli. Biotechniques 30:252-6, 2001 With B. Palmeros, J. Wild, W. Szybalski, S. LeBorgne, G. Hernandez Chavez, G. Gosset & F. Valle. A family of removable cassettes designed to obtain antibiotic-resistance free genomic modifications of Escherichia coli and other bacteria. Gene 247:255-64, 2000 With S. LeBorgne, B. Palmeros, F. Valle & G. Gosset. pBRINT-Ts: a plasmid family with a temperature sensitive replicon, designed for chromosomal integration into the lacZ gene of Escherichia coli. Gene 223:213-9, 1998 With P. Balbas, M. Alexeyev, I. Shokolenko & F. Valle. A pBRINT family of plasmids for integration of cloned DNA into the Escherichia coli chromosome. Gene 172:65-9, 1996 With P. Balbas, X. Alvarado & F. Valle. Plasmid pBRINT: a vector for chromosomal insertion of cloned DNA. Gene 136:211-3, 1993 With E. Merino, J. Osuna & X. Soberón. A general PCR-based method for single or combinatorial oligo nucleotide-directed mutagenesis on pUC/M 13 vectors. Biotechniques 12:508-10, 1992 With N. Flores, R. de Anda, L. Guereca, N. Cruz, S. Antonio, P. Balbas & F. Valle. A new expression vector for the production of fused proteins in Escherichia coli. Appl. Microbiol. Biotech. 25:267-71, 1986 With L. Covarrubias. Construction and characterization of new cloning vehicles VI. Plasmid pBR329, a new derivative of pBR328 lacking the 482-base pair inverted duplication. Gene 17:79-89, 1982 With L.L. Villa & R.R. Brentani. Human insulin: construction of a plasmid obtaining its coding sequences. Arq. Bras. Endocrin. Metabol. 25:61-4, 1981 With P.J. Greene, H.L. Heyneker, R.L. Rodríguez, M.C. Betlach, A.A. Covarrubías, K. Backman, D.J. Russel, R. Tait & H.W. Boyer. A general method for the purification of restriction enzymes. Nucleic Acid Research 5:2373-80, 1978 MEXICAN PATENTS With J.M. Camacho Zaragoza, G.T. Hernandez Chavez, F. Moreno Avitia, R. Ramírez Iñiguez, A. Martínez Jimenez & G. Gosset Lagarda. Cepas de Escherichia coli modificadas por ingenieria de vias metabolicas para la biosintesis de resveratrol y su uso en un nuevo proceso de co-cultivo (2017) With L.G. Ponce, L.M. Martínez Mejía, O.T. Ramírez Reivich, A. Martínez Jimenez & G.Gosset Lagarda. Cepas de Escherichia coli con alta capacidad para la producción de plásmidos y su uso en la producción de vacunas de ADN (2013) With G. Gosset Lagarda, A.J. Muñoz, G. Hernandez & R. de Anda. Cepas de Escherichia coli modificada para producir 3,4-hidroxi-L-fenilalanina (L-DOPA) 2011 With J. Osuña Quintero, J.L. Baez Viveros, G. Hernandez Chavez, X. Soberón Mainero & G. Gosset Lagarda. Versiones insensibles a inhibición alosterica y cataliticamente eficientes de la enzima corismato mutasa-prefenato deshidratasa y su aplicación para la producción de L-fenilalanina em microorganismos 274296 (2010) With G. Gosset Lagarda, A.R. Lara Rodríguez, M. del C. Vazquez Limón, A. López Munguía Canales & O.T. Ramírez Reivich. Estratégia para generar celulas insensibles a condiciones heterogeneas en biorreactores industriales a traves de mutaciones de vias metabolicas anaeróbias 324994 (2006) With G. Gosset Lagarda, A. Martínez Jimenez, V.H. Lagunas Muñoz, N. Cabrera Valladares, J.G. Davila Ramos, V.M. Gonzalez Zuñiga & V.P. Bustos Arcos. Producción de melaninas en microorganismos recombinantes (2004) With L. T. Casas de Terres, F. Bastarrachea Avilés, R. Quintero Ramírez, J.D. Carranco Rosas & E. Galindo Fentanes. Proceso para producir la enzima penicilina amidasa en celulas de E. coli 178107 (1995) With G. Gosset Lagarda, R. de Anda, R. Quintero, A. Martínez, F. Valle & N. Flores. Proceso fermentativo para obtener proteinas hibridas a partir de cepas de Escherichia coli 174910 (1994) With L. T. Casas de Terres, F. Bastarrachea Avilés, R. Quintero Ramírez & J.D. Carranco Rosas. Proceso mejorado para separar y purificar el acido6-aminopenicilanico (6-apa) preparado por hidrolisis enzimatico 172536 (1993) HONOURS Doctor Honoris Causa, Université de Liege (1994) International Scientist of the Year 2001, International Biographical Centre, Cambridge, England (2002)
Fortunato Blancas
Fortunato Blancas Sanchez, Peruvian entomologist (Acolla, Jauja Province 21 April 1919 – Lima 02 September 1988) DESCRIBED DIPTERA SPECIES Lutzomyia caballeroi 1989 with Caceres & Galati Phlebotomus bicornutus 1960 Phlebotomus gorbitzi 1960 HONORS Subgenus Blancasmyia 1995 (Diptera)
Felix Bacigalupo
Felix Antonio Bacigalupo Palomino, Peruvian agronomist (Lima 21 February 1927 – Developed a cotton seed flour and improved fish flour for human consumption Innovated on the utilization of potato, sweet potato and maize in pastamaking and breadmaking INVENTIONS An automatic machine for feeding of milk cows in according to their vital requirements A slide rule for measuring even animal feeding A food processor for human consumption that uses gases and eolic power A desaponifier of quinoa seeds producing quinoa flour and flakes
Federico Bonet
Federico Bonet Marco, Spanish-born Mexican entomologist, speleologist and palaeontologist (Madrid 18 October 1906 – Ciudad de Mexico 10 June 1980) DESCRIBED GENERA Protura Bolivaridia 1942 Silvestridia 1942 Fossil Protozoa Calcisphaerula 1956 Colomiella 1956 Fossil Ostracoda Microcalamoides 1956 Collembola Acanthisotoma 1942 Acherontides 1945 Folsomiella 1930 Harlomillsia 1944 Mesogastrura 1930 Orchesellides 1930 Pachytullbergia 1947 Pararrhopalites 1947 (with Tellez) Parasinella 1934 Parasira 1930 Sinelloides 1942 Spelaeogastrura 1945 Tafallia 1946 HONORS Bonetiella Rzedowski 1957 (Anacardiaceae) Bonetocardiella Dufour 1968 (Fossil Protozoa) Bonetesmus Chamberlin 1942 (Myriapoda) Bonetogastrura Thibaud 1974 (Collembola) Bonetrura Christiansen & Bellinger 1980 (Collembola)