Chelakara Sivarama Vaidyanathan, Indian biochemist (Palghat, Kerala State 14 November 1931 – Bangalore 01 September 1999)

Discovered new reaction pathways involving metabolism of phenolic and chloroaromatic compounds in plants, fungi and bacteria

First to study isolated enzyme systems involved in the aromatic ring fission in higher plants

First report of the metabolism of the fungicide Dexon by a soil bacterium

With N.G.K. Karanth, S.G. Bhat & V.N. Vasantharajan. Conversion of Dexon (p-Dimethylaminobenzenediazo Sodium Sulfonate) to N,N-dimethyl-p-Phenylenediamine by Pseudomonas fragi Bk9. Appl. Microb. (1974)

METHODS

With N.U. Khan & A.V. Kamath. Study of interfering substances in a simple, new spectrophotometric assay for phenylalanine ammonia-lyase. Biochem. Intern. 14(3):451-5, 1987

With S.P. Kunapuli & N.U. Khan. A simple and direct method for synthesis of S-mercuric N-dansyl cysteine. Ind. J. Biochem. (1984)

With M. Remika Prasad & M. Sugumaran. A new colorimetric method for the estimation of resorcinol. Anal. Biochem. (1977)

With P.M. Nair. A colorimetric method for determination of pyrocatechol and related substances. Anal. Biochem. 7(3):315-21, 1964

With K.V. Giri & A.N. Radhakrishnan. A simple paper chromatographic method for the study of transamination reactions. Nature 170:1025-6, 1952

BIOCHEMISTRY

With R. Santha, H.S. Savithri, N. Appaji Rao. 2,3 dihydroxibenzoic acid decarboxylase from Aspergillus niger: a novel decarboxylase. Europ. J. Biochem. 230(1):1104-10, 1995

With A.V. Kamath. New pathway for the biodegradation of indole in Aspergillus niger (1990)

With N. Narendra, M.A. Viswamitra, R. Venkateswara & K. Sankara Rao. Structure of cryptosin monohydrate: a new cardioactive glycoside. Acta Crystal. Sec C 43(8):1562-4, 1987 

With V. Subramanian. Anthranilate hydroxylase from Aspergillus niger: new type of NADPH-linked nonheme iron monooxygenase. J. Bacter. (1984)

With S.P. Kunapuli. Purification and characterization of a new indole oxygenase from the leaves of Tecoma stans L. plant Physiol. 71(1):19-23, 1983

With K.V. Giri, A.N. Radhakrishnan & K.S. Gopalkrishnan. Proline and hydroxyproline in leaves. Nature 170:579-80, 1980

With H.K. Sharma. A new mode of ring cleavage of 2,3 dihydroxybenzoic acid in Tecoma stans L. Europ. J. Biochem. (1975)

With S.G. Bmat & N. Ramanarayanan. Mandelic acid-4-hydroxylase, a new inducible enzyme from Pseudomonas convexa. Biochem. Biophys. Res. Comm. 52(3):834-42, 1973

With N.S. Sreellela, P.V. Subba Rao & R. Premkumar. A new anthranilic acid hydroxylase from Aspergillus niger. Purifications and properties. J. Biol. Chem. (1969)

With N.C. Pillai & K.V. Giri. A blood anticoagulant factor from the latex of Carica papaya. Part I. Purification and general properties. Proceed. Ind. Acad. Sciences Sec. B 42(6):316-24, 1955