Jorge Mardones Restat, Chilean pharmacologist (19 June 1908 – Santiago 03 November 1998)

Authored 175 scientific publications

Showed that human alcoholism displays a hereditary factor (1949). Due to this work won the Jellinek Memorial Award (1992)

Made pioneering studies about the alcoholic effects on nervous system development and the pharmacological basis of addiction

With E. Cruz Coke & M. Plaza de los Reyes proposed a scheme of a number of biochemical reactions in renal hypertension mechanism

With R. Cruz Coke. Detection of the segment of the population vulnerable to alcoholism, by means of a genetic marker. Bol. Oficina Sanit. Panam. 71(3):187-93, 1971

With S. Contreras & N. Segovia-Riquelme. A method for recognizing specific effects on ethanol intake by experimental animals. Alcohol 5(1):15-9, 1988

Papers in Science

With N. Segovia , F. Alcaino & A. Hederra. Effect of synthetic thioctic or alpha lipoic acid on the voluntary alcohol intake of rats. Science 119(3099):735-6, 1954

With J. Monsalve, M. Vial & M. Plaza de los Reyes. Tissue cytochrome c and prevention of experimental atherosclerosis. Science 114(2963):387, 1951