Raimundo Antonio Corneli Villegas Polanco, Venezuelan biophysicist (Caracas 14 September 1931 – Caracas 21 October 2014)

Authored over 80 scientific papers

Developed new techniques to ease the production of easily accessible food for the poorest

His wife, Gloria Teresa Mercader Guedez de Villegas, microscopist (La Guaira 12 November 1928 – 

SOME BIBLIOGRAPHY

RAIMUNDO

With J. Villegas, C. Sevcik & F.V. Barnola. Grayanotoxin, veratrine, and tetrodotoxin-sensitive sodium pathways in the Schwann cell membrane of squid nerve fibers. J. Gen. Physiol. 67:369, 1976

With F.V. Barnola. Sodium flux through the sodium channels of axon membrane fragments isolated from lobster nerve. J. Gen. Physiol. 67:81, 1976

With F.V. Barnola & J. Villegas. Sodium channels and tetrodotoxin binding sites in the axon and Schwann cell membrane. Fed. Proc. 33(5,2):1265, 1974

With F.V. Barnola & G. Camejo. Action of proteases and phospholipases on tetrodotoxin binding to axolemma preparations isolated from lobster nerve fibers. Biochim. Biophys. Acta 318(1):61-8, 1973 

With F.V. Barnola & G. Camejo. Tetrodotoxin receptors in plasma membranes isolated from lobster nerve fibers. Biochim. Biophys. Acta 298 (1):84-94, 1973

With F.V. Barnola. Ionic channels and nerve membrane constituents: tetrodotoxin-like interaction of saxitoxin with cholesterol monolayers. J. Gen. Physiol. 59:33, 1972

With F.V. Barnola & G. Camejo. Ionic channels and nerve membrane lipids: cholesterol-tetrodotoxin interaction. J. Gen. Physiol. 55:548, 1970

With J. Villegas & M. Gimenez. Nature of the Schwann cell electrical potential: effect of the external ionic concentrations and a cardiac glycoside. J. Gen. Physiol. 51:47-64, 1968

With G. Camejo. Tetrodotoxin interaction with squid nerve membrane lipids. Biochim. Biophys. Acta 163:421-3, 1968

With J. Villegas & L. Villegas. Sodium, potassium and chloride concentrations in the Schwann cell and axon of the squid nerve fiber. J. Gen. Physiol. 49:1-7, 1965

With C. Caputo & L. Villegas. Diffusion barriers in the squid nerve. The axolemma and the Schwann layer. J. Gen. Physiol. 46:245-55, 1962

With M. Gimenez & L. Villegas. The Schwann-cell electrical potential in the squid nerve. Biochim. Biophys. Acta 62:610, 1962

With F.V. Barnola. Characterization of the resting axolemma in the giant axon of the squid. J. Gen. Physiol. 44:963, 1961

With F.V. Barnola. Equivalent pore radius in the axolemma of the giant axon of the squid. Nature 188:762, 1960

With R.C. Barton & A.K. Solomon. The entrance of water into beef and dog red cells. J. Gen. Physiol. 42:355-69, 1958

GLORIA

With N.J. Lane & J. Villegas. Freeze-fracture studies on the giant axon and ensheathing Schwann cells of the squid. J. Neurocytol. 16:11-21, 1987

With J. Villegas. Structural complexes in the squid axon membrane sensitive to ionic concentrations and cardiac glycosides. J. Cell Biol. 69:10-28, 1976

Effects of cholinergic compounds on the axon-Schwann cell relationship in the squid nerve fiber. Fed. Proc. Fed. Am. Soc. Exp. Biol. 34:1370, 1975

With J. Villegas. Acetylcholinesterase localization in the giant nerve fiber of the squid. J. Ultrastruct. 46:149-63, 1974

With F.A. Rawlins & E.T. Hedley-White. Fine structural localization of cholesterol 1,2-3H in degenerating and regenerating mouse sciatic nerve. J. Cell Biol. 52:615, 1972

With F.A. Rawlins, E.T. Hedley-White & B.G. Uzman. Reutilization of cholesterol 1,2-H* in the regeneration of peripheral nerve: an autoradiographic study. Lab. Invest. 22:237-490, 1970  

Ultrastructure of the human retina. J. Anat. 98:501-13, 1964

Ultraestructura de la fibra nerviosa gigante del calamar. Acta Cient. Venez. Suppl. I: 11-22, 1963

With B.G. Uzman. A comparison of nodes of Ranvier in sciatic nerves with node-like structures in optic nerves of the mouse. J. Biophys. Biochem. Cytol. 7:761, 1960  

Electron microscopic study of the vertebrate retina. J. Gen. Physiol. 43(2):15-43, 1960

Electron microscopic study of the giant nerve fiber of the giant squid Dosidicus gigas. J. Ultrastruct. Res. 26:501-14, 1960

BOTH

Squid axon ultrastructure. Curr. Top. Memb. Transport 22:3-37, 1984

With A.M. Correa. Nerve sodium channel in membrane vesicles and in reconstituted proteoliposomes. Effect of anemone toxin. II. Biophys. J. 41:143, 1983 

Nerve sodium channel incorporation in vesicles. Ann. Rev. Biophys. Bioeng. 10:387-419, 1981

With Z. Suarez Mata. Reconstitution of the sodium channel with partially solubilized lobster nerve membrane. J. Physiol. 77:1077-86, 1981

With M. Condrescu-Guidi & Z. Suarez Mata. Characterization of the nerve membrane sodium channel incorporated into soybean liposomes. A sodium channel active particle. Ann. N.Y. Acad. Sci. 358:183-203, 1980

With F.V. Barnola & E. Racker. Incorporation of the sodium channel of lobster nerve into artificial liposomes. Biochem. Biophys. Res. Comm. 79:210-7, 1977

With F.V. Barnola & C. Sevcik. Action of the sterol-binding form of filipin on the lobster axon membrane. Biochim. Biophys. Acta 426:81-7, 1976

With R. Di Polo & J. Villegas. Nonelectrolyte permeability, sodium influx, electrical potentials, and axolemma ultrastructure in squid axons of various diameters. J. Gen. Physiol. 57:623-37, 1971

With F.V. Barnola & G. Camejo. Characterization of two different membrane fractions isolated from the first stellar nerves of the squid Dosidicus gigas. Biochim. Biophys. Acta 193:247, 1969

With B. Bruzual. Equivalent pore radius of the axolemma of resting and stimulated squid axons. J. Gen. Physiol. 55:548, 1968

Ultrastructural studies of the squid nerve fibers. J. Gen. Physiol. 51:44-60, 1968

With M. Blei, F.C. Herrera & J. Villegas. Nonelectrolyte penetration and sodium fluxes through the axolemma of resting and stimulated medium sized axons of the squid Doryteuthis plei. J. Gen. Physiol. 50:43, 1966 

Les couches superficielles de la fibre nerveuse du calmar. Actual Neurophys. 6:55-68, 1965

With F.C. Herrera & M. Blei. Sodium influx and non-electrolyte penetration in stimulated squid axons. J. Cell. Comp. Physiol. 66:155, 1965

With M. Blei. Penetration of non-electrolyte molecules in resting and stimulated squid nerve fibers. J. Gen. Physiol. 48:35, 1965

Extracellular pathways in the peripheral nerves fibers: Schwann-cell layer permeability to thorium dioxide. Biochim. Biophys. Acta 88:231-3, 1964

Neuron-glia relationship in the bipolar cell-layer of the fish retina. J. Ultrastruct. Res. 8:89-106, 1963

With L. Villegas & M. Gimenez. Schwann cell and axon electrical potential differences. Squid nerve structure and excitable membrane location. J. Gen. Physiol. 46:1047-64, 1963

Morphogenesis of the Schwann channels in the squid nerve. J. Ultrastruc. Res. 8:197-205, 1963

The endoneurium cells of the squid giant nerve and their permeability to ¹⁴C-glycerol. Biochim. Biophys. Acta 60:202-4, 1962

The ultrastructure of the giant nerve fiber of the squid: axon-Schwann cell relationship. J. Ultrastruct. Res. 3:362-73, 1960

Characterization of membranes in the giant nerve fiber of the squid. J. Gen. Physiol. 43:73, 1960