Yellapragada Subbarao (Subba Row), Indian pharmacist and biochemist in United States (Bhimavaram, Andhra Pradesh State 12 January 1895 – Pearl River, New York State 08 August 1948)

Authored over 100 papers

CONTRIBUTIONS

Developed Fiske-Subba Row calorimetric method to estimate phosphorus in tissues and body fluids (1924)

With C. Fiske, P. Eggleton & G.P. Eggleton discovered phosphagen in muscle (1927)

With Fiske discovered that phosphocreatine and ATP were sources of muscle power (1927-9)

With Fiske isolated ATP and phosphocreatine independently from Lohmann (1929)

With Szent-Gyorgy isolated pyridoxine

Isolated and synthesized folic acid (1945)

Developed a method to synthesize folic acid

Found that folic acid cures tropical sprue

Discovered antifolates

ANTIBIOTICS

With Duggar discovered aureomycin (1948) and tetracycline

Discovered diethyl carbazamin

Anti-cancer drug Methotrexate (1948)  

Hetrazan against elephantiasis

Hydrazide against tuberculosis

Polymyxin used in cattle feed

HONORS

Antibiotic Subbamycin

Genus Subbaromyces Hesseltine 1953 (Fungi)