Elias Ramón de la Sota
Elias Ramón de la Sota, Argentine botanist and paleobotanist (San Miguel de Tucumán 27 September 1932 – La Plata 20 January 2014) DESCRIBED LIVING & FOSSIL PLANTAE TAXA Fossil Genera Dizeugotheca 1961 with Archangelsky Eligodendron 1966 with Archangelsky Living Species Asplenium lilloanum 1973 Blechnum austrobrasilianum 1975 Blechnum pampasicum 2005 with Durán Blechnum rosenstockii 1973 Cheilanthes volcanensis 1972 Elaphoglossum yungense 1973 Hymenophyllum capurroi 1972 Marsilea punae 1976 Microgramma mortoniana 1973 Pecluma barituensis 2007 with Martínez Pecluma oranense 1995 Polypodium apagalolepis 1967 Polypodium bolivari 1967 Polypodium bradei 1965 Polypodium jahannis-bladwinii with Mickel Polypodium mickelii 1967 Polypodium oranense 1960 Polypodium ruiz-lealii 1960 Polypodium singeri 1960 Polypodium venturii 1961 Pteris famatinensis 1972 Salvinia herzogii 1962 Salvinia nuriana 1997 with Cassá Thelypteris catamarcensis 1973 Thelypteris jujuyensis 1973 Thelypteris nubicola 1973 Thismia singeri 1960 Fossil Species (with Archangelsky) Ashicaulis herbstii 1960 Asterotheca falcata 1962 Asterotheca menendezii 1962 Dichomopteris hirudinis 1960 Dizeugotheca neuburgiae 1960 Dizeugotheca waltoni 1960 Eligodendron branisae 1966 Millerocaulis herbstii 1963 Millerocaulis sanctaecrucis Osmundacaulis patagonica 1962 Pecopteris frenguelii HONOURS Sotasporites Archangelsy & Archangelsky 2006 (Fossil Sporae)
Eduardo Schmitter Villada
Eduardo Schmitter Villada, Mexican mineralogist and petrographer (Toluca 21 June 1904 – 1982?) From Swiss father SOME BIBLIOGRAPHY With Z. de Cserna, P.E. Damon, D.E. Livingston & L.J. Kulp. Edades isotopicas de rocas metamorficas del centro y sur de Guerrero y de una monzonite cuarcífera de Sinaloa. Bol. Inst. Geol. UNAM 26:195-204, 1974 With Z. de Cserna, C. Fries Jr, J. Rincón Orta & J. Solorio-Munguia. Nuevos datos geocronometricos paleozoicos del sur de Mexico. Bol. Asoc. Mex. Geol. Petroleros 26:195-204, 1974 With C. Fries Jr., Z. de Cserna, C. Rincón Orta, A. Wesley & J. Solorio-Munguia. Edad Precámbrica tardia del Esquisto Taxco, Estado de Guerrero. Bol. Asoc. Mex. Geol. Petroleros 26:183-93, 1974 With C. Fries Jr, C. Rincón-Orta, L.T. Silver, F.W.McDowell, J. Solorio-Munguia & Z. de Cserna. Nuevas aportaciones a la geocronologia de la faja tectonica Oaxaqueña. Bol. Asoc. Mex. Geol. Petroleros 26:157-82, 1974 With Z. de Cserna, C. Fries Jr, C. Rincón Orta, L.T. Silver, M. Wesley & J. Solorio-Munguía. Datos geocronometricos terciarios de los estados de Mexico, Morelos y Guerrero. Bol. Asoc. Mex. Geol. Petroleros (1974) With C. Fries Jr., C. Rincón Orta, J. Solorio-Munguia & Z. de Cserna. Uma edad radiometrica ordovicica de Totoltepec, Estado de Puebla (1970) Nelsonita de ilmenita y magnetita de la región de Huitzo, Estado de Oaxaca (1970) With Z. de Cserna, C. Rincón Orta & J. Solorio-Munguia. Una edad radiometrica permica temprana de la región de Placer de Guadalupe, noreste de Chihuahua. Bol. Soc. Geol. Mex. 31(1):65-73, 1968 With C. Fries Jr, P.E. Damon, D.E. Livingston & R. Erickson. Edad de las rocas metamorficas en los cañones de La Peregrina y de Caballeros, parte centro-occidental de Tamaulipas (1962) With C. Fries Jr, P.E. Damon & D.E. Livingston. Rocas precámbricas de edad grenvilliana de la parte central de Oaxaca em el sur de Mexico. Bol. Inst. Geol. UNAM 64:45-53, 1962 Clasificación basada en el análisis térmico diferencial de materiales arcillosos colectados en diferentes regiones del país. Bol. Inst. Geol. Mexico 59:105-11, 1959 With C. Fries Jr. Geology of the Huahuaxtla Mercury District State of Guerrero, Mexico (1948) With C. Fries Jr. Tin-bearing placers near Guadalcazar, State of San Luis Potosí, Mexico. Bull US Geol. Surv. (1948) With C. Fries Jr. Scheelite deposits in the northern part of the Sierra de Juarez, Northern Territory, Lower California, Mexico (1945) Metodo para laminar ejemplares de microfosiles. Bol. Soc. Geol. Mexico 11(7), 1944 A specimen of paraguanajuatite with guanajuatite and scheelite from León, Guanajuato, Mexico HONORS Schmitterite Gaines 1971 (Mineral)
Edson Saad
Edson Abdalla Saad, Brazilian cardiologist (Igarapava, São Paulo State 12 July 1935 – Rio de Janeiro 03 June 2005) From Lebanese parents ACHIEVEMENTS Described systematically the digestive lesions of Nicolas-Favre disease and was the first to treat them employing glucocorticoids With S. Coutinho & J. Rodrigues da Silva first to demonstrate the existence of clinical forms of schistosomiasis with post-sinusoidal portal hypertension and describe its clinical and anatomopathological figure Authored works distinguishing schistosomiasis from other hepatopathies using supra-hepatic venography Performed the first systematic hemodynamical studies in Chagas disease and the first left catheterization in this disease (1969) Performed the first in vivo coronariographies in Chagas disease Tracked the path of cardiac decompensation in Chagas disease and its many evolutive hemodynamic phases Showed the existence of a vagal hipertonus at A-V node level in Chagas disease First to show the role that play the echocardiogram in assessing the cardiac endangerment in Chagas disease Showed the incidence of auto-antibodies and the role of lymph cells in Chagas disease With Widerhecker, Panerai and Grynzpan developed a technique for outer detection of His bundle electrogram With Grynzpan & Mello developed a videodensimetric catch and processing system of signs that permit measuring ventricular volumes and valvar regurgitations LINKS http://www.arquivosonline.com.br/entrevistas/drsaad/carreira.asp ( Portuguese)
Dulal Pada Sadhu
Dulal Pada Sadhu, Indian nutritional physiologist (Kapilmuni, Bangladesh 09 May 1916 – ?) ACHIEVEMENTS Discovered the role of deamination and transamination on the protein action mechanism in rats and ruminants Discovered the fundamental mechanism in the field of energy exchange in the living organism Demonstrated the stenothermal stage in the evolution of thermal regulation in animals SOME BIBLIOGRAPHY Effect of feeding higher doses of urea on the rumen metabolism in goat. Ind. Vet. J. 45:735-9, 1986 With S.N. Das. Effect of acetazolamide on insulin sensitivity in dogs with alloxan diabetes. Ind. J. Physiol. Pharmacol. 22:301-4, 1978 With S.K. Basu. Skin thermometry of rats under different ambient temperatures. Ind. J. exp. Biol. 15(12), 1977 With S.S. Tripathi & M.V.N. Rao. Effect of thermal stress on certain blood constituents in hill steers. Ind. J. Anim. Health 17:47, 1976 With B. Singh & B.B. Mahapatro. Chemical composition of cattle and buffalo spermatozoa and seminal plasma under different climatic conditions (1969) With D.R. Chowdhry. Consumption of oxygen by sweat glands of Indian zebu cattle. Nature 198:311, 196? With D.R. Chowdhry. Rate of evaporation from different regions of the skin of Indian zebu cattle. Nature 189:491, 1961 With S. Chaudhuri. Thyroid activity at higher ambient temperatures. Nature 192:560-1, 1961 With S. Chaudhuri. The role of the adrenergic system in the thermoglycemic response in baby rabbits. Am. J. Physiol. 199:727-8, 1960 With A. Goswami. Polyenoic acid in hypercholesterolemia induced by pyridoxine deficiency in rats. Nature 187:786, 1960 With K.P. Chakravorti. Some aspects of the histochemical studies on the oviduct of the pigeon, Columba livia Gmelin. Proc. Zool. Soc. Calcutta 12:9-14, 1959 With N.K. Das. Haematological studies in Indian goats. Proc. 42nd Ind. Sci. Congress 3:347, 1955 With S. Mookerjea. Metabolic depression by arsenite and malonate and cholesterologenesis. Arch. Biochem. Biophys. 58:232-6, 1955 With S.N. Ray. Histamine and carbohydrate metabolism (1955) Influence of lactose on the transglycosidation of sphingosine base in the rat brain. Am. J. Physiol. 175:283-4, 1953 Role of fat on utilization of lactose in milk by rats and rabbits. Proc. Soc. Exp. Biol. Med. 77:585, 1952 With B.L. Truscott. Effect of hypervitaminosis A and of reticuloendothelial system blockade on the thyroid. Anat. Rec. 100:719, 1948 With B.L. Truscott. Hypervitaminosis A and distribution of body iodine. Endocr. 43:120-8, 1948 Vitamin A, iodide and thyrotropic hormone content on the anterior pituitary. Am. J. Physiol. 152:263, 1948 Physiological mechanism of experimental goitrogenesis. Am.J. Physiol. 152:150, 1948 With S. Brody. Thiouracil, basal metabolism and specific dynamic action. Am. J. physiol. 151:130-3, 1947 With S. Brody. Excess vitamin A ingestion, thyroid size and energy metabolism. Am, J. Physiol. 149:400-3, 1947 With S. Brody. The nutritional significance of milk with special reference to milk sugar. Scient. Month. 64(1):5-13, 1947 Growth and development with special reference to domestic animals. The specific dynamic action of nutrients with special reference to the effects of vitamins and hormones (1947)
Diogenes Santiago Santos
Diógenes Santiago Santos, Brazilian microbiologist, biochemist and molecular biologist (Gandu, Bahia State 28 June 1942 – Porto Alegre 23 June 2017) Authored about 200 scientific works (with about 3,000 citations and h index 31) Solved the three-dimensional structure of 39 proteins deposited in Protein Data Bank (PDB) With I. Schrank, A. Zaha & E.F. Araújo. Construction of a gene library from Azospirillum brasilense and characterization of a recombinant containing the nif structural genes. Braz. J. Med. Biol. Research 20:321-30, 1988 With J.C.D. Hinton, A. Sarafi, J. Sidebotham, C. Higgins, T.A. Owenhughes & G.D. Pavitt. H-NS A Novel DNA-Binding Protein Involved in Maintaining Chromatin Structure and Regulating gene Expression. Journal of Cellular Biochemistry 8(Suppl.), 295-6, 1993 With J. Rakonjac, M. Milic, R. Ivanisevic & D. Savic. Nov a New Genetic Locus that Affects Response of Escherichia coli to Novobiocin. Molecular Microbiology, 6(11):1547-53, 1992 With A. H. R. Paz, S. Rief, E. Wolf, K. Prelle & E.O.C. Lima. Mouse embryonic stem cells: The establishment of the system to produce differentiated cell types in vitro. Acta Scientiae Veterinariae 31(1):51-4, 2003 With J.S. de Oliveira, L.A. Basso, M. Palaci, R. Dietze & I.S. Moreira. An inorganic iron complex that inhibits wild type and an isoniazid-resistant mutant 2 trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis. Chemical Communications 3:312-3, 2004 With F. Canduri, V. Fadel, L. A. Basso, M.S. Palma & W.F. Azevedo Jr. New catalytic mechanism for human Purine nucleoside Phosphorilase. Biochemical and Biophysical Research Communications 327:646-9, 2005 With E.H. de Souza, D.L. Pontes, I.C. N. Diogenes, E. Longhinotti, L.G.F. Lopes, J.S. de Oliveira, L.A. Basso & I.S. Moreira. Electron Transfer Kinetics and Mechanism Study of the Thionicotinamide Coordinate to the Ironpentacyano (II) and (III) Complexes: A Model System for the in vitro Activation of Thioamides anti-tuberculosis drugs. Journal of Inorganic Biochemistry 99:368-75, 2005 With B.A.D Neto, F.S Mancilha, I.B. Vasconcelos, C. Thum, L.A. Basso & J. Dupont New Sensitive Fluorophores for Selective DNA detection. Organic Letters 9:4001-4, 2007 With C.L. Fernandes, A. Breda, L.A. Basso & O.N. de Souza. A Structural Model for Chorismate Synthase from Mycobacterium tuberculosis in Complex with Coenzyme and Substrate. Computers in Biology and Medicine 37:149-58, 2007 With I.C. Werlang, C. Schneider & L.A. Basso. Identification of Rv3852 as a nucleoid-associated protein in Mycobacterium tuberculosis. Microbiology 155:2652-63, 2009 With L.A. Basso, C.Z. Schneider, A. J. A. B. Santos & M.M. Campos. An inorganic Complex that Inhibits Mycobacterium tuberculosis Enoyl Reductase as a Prototype of a New Class of Chemotherapeutic Agents to Treat Tuberculosis. Journal of the Brazilian Chemical Society 7:1384-89, 2010 With E.H. de Souza, L.A. Basso, I.C.N. Diogenes, E. Longhinotti, L.G. F. Lopes & I. S. Moreira. Isoniazid metal complex reactivity and insights for a novel anti-tubercular drug. JBIC. Journal of Biological Inorganic Chemistry 17:275-83, 2012 With M.C de Moraes, R. G. Ducati, A.J. Donato, L.A. Basso, C.L. Cardoso & Q.B. Cass. Capillary bioractors based on human Purine Nucleoside Phosphorylase: a new approach for ligands indetification and characterization. Journal of Chromatography 1232:110-5, 2012 With I. Pauli, R.N. dos Santos, D.C. Rostirolla, L.K. Martinelli, R.G. Ducati, L.F.S. Timmers, L.A. Basso, R.V.C. Guido, A.D. Andricopulo & O.N. Souza. Discovery of New Inhibitors of Mycobacterium tuberculosis InhA Enzyme Using Virtual Screening and a 3D-Pharmacophore-Based Approach. Journal of Chemical Information and Modeling 53:2390-2401, 2013 With D. Renck, P. Machado, A.A. Souto, L.A. Rosado, T. Erig, M.M. Campos, C.B. Farias, R. Roesler, Luis F.S. Timmers, O.N. de Souza & L.A. Basso. Design of Novel Potent Inhibitors of Human Uridine Phosphorylase-1: Synthesis, Inhibition Studies, Thermodynamics, and in Vitro Influence on 5-Fluorouracil Cytotoxicity. Journal of Medicinal Chemistry 56:8892-02, 2013 With P. Machado, E. Ritter, A.J.B. dos Santos, C. Neves & L.A. Basso. Ultrasound-assisted improvement of drug solubility: a simple and useful method for the formation of salts from 4-hydroxy-6-methyl-3-nitropyridin-2(1H)-one. Monatshefte fur Chemie , 144:1165-70, 2013 With D. Renck, A. Santos Jr., P. Machado, G.O. Petersen, T. J. Lopes, M.M. Campos, & L.A. Basso. Human uridine phosphorylase-1 inhibitors: a new approach to ameliorate 5-fluorouracil induced intestinal mucosositis. Investigational New Drugs (2014) With G.O. Petersen, S. Saxena, J. Renuka, V. Soni, P. Yogeeswari, C.V. Bizarro & D. Sriram. Structure-based virtual screening as a tool for the identification of novel inhibitors against Mycobacterium tuberculosis 3-dehydroquinate dehydratase. Journal of Molecular Graphics & Modelling , (2015) With G. Cattaneo, D. Ubiali, E. Calleri, M. Rabuffetti, G.C. Höfner, K.T. wanner, M.C. de Moraes, L.K.B. Martinelli, G. Speranza & G. Massolini. Development, validation and application of a 96-well enzymatic assay based on LC-ESI-MS/MS quantification for the screening of selective inhibitors against Mycobacterium tuberculosis purine nucleoside phosphorylase. Analytica Chimica Acta 943: 89-97, 2016 With T. Gazzi, M. Rotta, A. Villela, V. Rodrigues Jr., L. Martinelli, F. Sales, E. de Sousa, M. Campos, L.A. Basso & P. Machado. Synthesis, Inhibition of Mycobacterium tuberculosis Enoyl-acyl Carrier Protein Reductase and Antimycobacterial Activity of Novel Pentacyanoferrate(II)-isonicotinoylhydrazones. Journal of the Brazilian Chemical Society (2017) With N.D.M. Sperotto, C.D. Roth, V.S. Rodrigues Jr., C.E. Neves et al. Design of novel inhibitors of human thymidine phosphorylase: synthesis, enzyme inhibition, in vitro toxicity and impact on human glioblastoma cancer. J. Med. Chem. 62(3):1231-45, 2019 BRAZILIAN AND FOREIGN PATENTS With P. Machado, L.A. Basso & K. Pissinate. Compound, method for producing the compound, pharmaceutical composition, use of the compound for preparing a medicinal drug for treating a disorder caused by bacteria of the genus Mycobacterium and method for treating a disorder caused by bacteria of the genus Mycobacterium BR1020150146809 & WO2016201541 A1 (2015) With L.A. Basso, P. Machado & D. Renck. Uso de 6-hidroxi-2-piridonas e seus derivados na preparação de uma composição farmacêutica que atue pela inibição da enzima uridina fosforilase humana (Use of 6-hydroxy 2 pyridones and derivatives thereof for preparing a pharmaceutical composition that act by inhibiting the human uridine phosphorylase enzyme ) BR10 2013022567-3 A232 (2013) & US9700547B2 (2014) With L.A. Basso, P. Machado & T.P. Gazzi. Method for synthesizing lanthanide-based coordination compounds, gadolinium (III)-based coordination compound and use of same BR102013023479-6 (2013) & WO2015035483A1 (2015) With E.L. Batista Jr., L.A. Basso, A.A. Souto, A.J. Donato & C. Deves. Deazapurinas, processo de preparo, composições farmacêuticas compreendendo deazapurinas e seu uso em osteoporose e/ou perda óssea,
Dimitri Sucre
Dimitri Ivan Sucre Benjamín, Panamanian-born Brazilian botanist and nurseryman (23 December 1935 – Rio de Janeiro 28 August 2000) DESCRIBED VALID PLANTAE SPECIES Dioscorea margarethia 1970 with Barroso & Guimarães Dioscorea pseudomacrocapsa 1971 with Barroso & Guimarães Dorstenia alberti 1974 with Carauta & Valente Dorstenia grazielae 1973 with Carauta & Valente Dorstenia milaneziana 1974 with Carauta & Valente Ferdinandusa edmundoi 1962 Galianthe dichasia 1970 with Costa Malanea centralis 1963 Mitracarpus baturitensis 1971 Mitracarpus flagellatus 1969 Mitracarpus froesii 1971 Neoregelia lymaniana 1974 with Braga Pitcairnia burle-marxii 1971 with Braga Psylllocarpus psyllocarpoides 1971 Remijia cinchonicarpa 1962 Remijia grazielae 1962 Remijia hirsuta 1962 Remijia kuhlmannii 1962 Spermacoce egleri 1970 with Costa Spermacoce limae 1971 Spermacoce noronhensis 1969 Tillandsia grazielae 1975 with Braga Tillandsia nuptialis 1969 with Braga HONORS Sucrea Soderstrom 1981 (Poaceae)