Antonio Carlos Pacheco e Silva
Antonio Carlos Pacheco e Silva, Brazilian neuropsychiatrist (São Paulo 29 May 1898 – São Paulo 27 May 1988) Authored original studies about general pathology of syphilitic infection of the nervous centers with many citations in literature Related the presence of Schaudinn spirochaeta in the tissues of nervous centers within the lymphatic channels (Virchow-Robin spaces) and in the proximity of the blood vessels, as well as in the intimate fibers of optic vessels Demonstrated the granular form of syphilis germ in brain With C. Tretiakoff. Uma forma particular da síndrome peduncular alterna. Mem. Hosp. Juqueri 1:101-6, 1924 Eponym of Pacheco e Silva-Oliveira Bastos blepharospasm sign in Parkinson disease OFFICES President, World Federation for Mental Health (1960-1)
Antonio & Therezinha Paiva
Antonio Cechelli de Mattos Paiva, Brazilian biochemist (Mogi Mirim, São Paulo State 21 June 1929 – São Paulo 18 May 2006) Authored about 150 papers With his wife gained international recognition for their work on polypeptides syntheses SYNTHESES OF PEPTIDES With T.B. Paiva et al. New specific antagonists of angiotensin I and II (1973) With T.B. Paiva & M.E. Miyamoto. An analogue peptide of pepsitensin (1973) With T.B. Paiva & M.E. Miyamoto. Synthesis of a proposed pepsitensin. J. Med. Chem. 16(3):280, 1973 With M. Tominaga, J.M. Stewart & T.B. Paiva. New bradykinin potentiating peptides (1975) With G. Goissis & V.L.A. Nouailhetas. Biologically active retroenantiomers of angiotensin peptides (1976) With C.R. Nakaie, M.E.M. Oshiro & G. Goissis. New peptide analogues of angiotensin II (1977) With E.B. Sabia, M. Tominaga & T.B. Paiva. New analogues of snake venom peptides (1978) With C.R. Nakaie, E.G. Silva, E.M. Cilli, R. Marchetto, S. Schreier & T.B. Paiva. Synthesis and pharmacological properties of TOAC-labeled angiotensin and bradykinin analogs. Peptides 23(1):65-70, 2002 OTHER CONTRIBUTIONS With T.B. Paiva & J.L. Prado demonstrated that angiotensin and pepsitensin were distinct substances Non-identity between pepsitensin and hypertension revealed by paper electrophoresis. Science 120:611, 1954 With T.B. Paiva. The importance of the N-terminal of angiotensin II for its pressor and oxytocic activities. Biochem. Pharmacol. 5:181, 1960 With V.L.A. Nouailhetas, M.E. Miyamoto, G.B. Mendes & T.B. Paiva. New specific angiotensin inhibitors. J. Med. Chem. 16(1):6-9, 1973 With L. Oliveira & G. Vriend. A common step for signal transduction in G protein-coupled receptors. J. Comput. Aided Mol. Des. 7:649-58, 1993 A novel enzyme with activity tonin-like from rat submandibular gland (1993) With N.L. Miasiro. Specific endothelin receptor agonists and antagonists disclose two new Etb receptors in the guinea pig ileum. Abst. XII Intern. Congr. Pharmacology p.572, 1994 With L. Oliveira & G. Vriend. A low resolution model for the interaction of G proteins with G-protein coupled receptors. Protein Engin. 12:1087-95, 1999 With M. Tominaga, S.R. Barbosa, S. Schreier, C.R. Nakaie et al. Fmoc-POAC: [(9-fluorenylmethyloxycarbonyl-2,2,5,5-tetramethylpyrrolidine-N-oxyl-3-amino-4-carboxylic acid]: A novel protected spin labeled amino acid for peptide and protein chemistry. Chem. Pharm. Bulletin 49(8):1027-9, 2001 With L. Oliveira, P.B. Paiva & G. Vriend. Sequence analysis reveals how G protein-coupled receptors transduce the signal to the G protein. Proteins 52:553-60, 2003 BRAZILIAN PATENTS With C.R. Nakaie, M. Tominaga, S.R. Barbosa, R. Marchetto & S. Schreier. Síntese de um novo derivado de aminoacido paramagnético (epm-5) para uso em marcação de diferentes macromoléculas e sistemas de interesse químico-biológico PI9903137-0 A2 (1999) With J.B. Pesquero, J.L. Pesquero, R.C. Araújo, M.A.S. Mori & M.S. Bader. Mecanismos e drogas utilizados no tratamento de diabetes, obesidade e controle dos distúrbios da fome (2005) HONOURS 100 Best Scientists of the World, Banning Foundation, Cambridge, United Kingdom (2006) His wife, Therezinha Bandiera de Paiva, pharmacologist (Paraguaçu Paulista, São Paulo State 20 April 1929 – São Paulo 15 March 2011) From Italian descent See above BRAZILIAN PATENT With E. Achar, A.H. Campos, W.S. Almeida, R.A.N. Achar & N. Schor. Uso da amitriptilina, composição, forma farmacêutica, produto alimentício e método para prevenção, tratamento e eliminação de cálculos renais em animais PI0400994-0 A2 (2004) With E. Achar, A.H. Campos, W.S. Almeida, R.A.N. Achar & N. Schor. Uso da amitriptilina, composição, forma farmaceutica, produto alimentício e método para prevenção, tratamento e eliminação de cálculos renais em humanos PI0400995-9 A2 (2004)
Anita Dolly Panek
Anita Dolly Panek, Polish-born Brazilian biochemist (Cracow 01 September 1930 – Authored about 160 papers Determined the primary function of trehalose in baker’s yeast as an energy source for cell division Function of trehalose in yeast cells. Arch. Biochim. Biophys. 98:349, 1962 Showed that endogenous trehalose protects cells against damage caused by freezing (1988) Demonstrated that the trehalose is required for survival of cells when submitted to various kinds of stresses such as dehydration, ethanol, heat and germination Purified partially baker’s yeast trehalase With N.O. Souza. Purification and properties of baker’s yeast trehalase. J. Biol. Chem. 239(6):1671-3, 1964 Showed the existence of a trehalose transport mechanism in yeasts With P.S. Araujo, A.C. Panek, J.H. Crowe & L.M. Crowe. Trehalose-transporting membrane vesicles from yeasts. Biochem. Int. 24(4):731-7, 1991 METHODS, TECHNIQUES AND PROCESSES With A.S. Martins, D.N. Peixoto, L.M.C. Paiva & C.L. A. Paiva. A simple method for obtaining reusable reactors containing immobilized trehalase: Characterization of a crude trehalase preparation immobilized on chitin particles. Enzyme and Microbial Technology 38:486-492, 2006. With B.U. Stambuk, J.H. Crowe, L.M. Crowe & P.S. Araújo. A Dependable Method For The Synthesis Of [C14] Trehalose. Anal. Biochem. 212:150-153, 1993. With R.M. Ferreira, M.B. Dutra, V.M.F. Paschoalin & J.T. Silva. A new method for the purification of yeast Hsp26p (1999) With R.M.A. Soler et al. A simple enzymatic method for trehalose quantification (1996) With P.S. Araújo, A.C. Panek & R.Ferreira. Determination of trehalose in biological samples by a simple and stable trehalase preparation. Anal. Biochem. 176(2):432-6, 1989 With A.B. Valle & J.R. Mattoon. Colorimetric determination of succinic acid using yeast succinate dehydrogenase. Anal. Biochem. 91(2):583-99, 1978 PATENTS With E.C.A. Eleutherio patented a process for protecting and maintenance of human, animal and plant tissues employing trehalose PI9400068-9 (1994) With C. Meleiro & V.M.F. Paschoalin developed a process for obtaining trehalose from Saccharomyces cerevisiae PI9303490-3 (1993) With N. Bachinski, V.M.F. Paschoalin & C.L.A. Paiva developed a process to obtaining, purification and immobilization of trehalase from Escherichia coli. Process employing soluble and/or immobilized trehalase in enzymatic dosage of trehalose (1993)
Angelo Pires do Prado
Angelo Pires do Prado, Brazilian entomologist (São Lourenço do Sul, Rio Grande do Sul State 01 February 1942 – Campinas, São Paulo State 25 August 2013) Authored one book and 117 papers DESCRIBED DIPTERA TAXA Family Syringogastridae 1969 Genera Aristocerina 1975 with Borgmeier Brachyphlebina 1975 with Borgmeier Brachycosta 1976 Borgmeieria 1976 Borgmeiriphora 1976 Colyeria 1975 with Borgmeier Cyrtophorina 1975 with Borgmeier Dorsochaeta 1975 with Borgmeier Lenkokroeberia 1966 Lopesiodinia 1973 Neotraginops 1973 Paraphryssopoda 1983 with Guimarães & Papavero Platydipteron 1975 with Borgmeier Stylusa 1975 with Borgmeier Trichocerina 1975 with Borgmeier Species About 100 HONORS Pradomyia Gaimard 2007 (Diptera)
Andrés Posada Arango
Andrés Posada Arango, Colombian physician, naturalist, geographer, ethnographer and historian (Medellín 11 February 1839 – Medellín 13 March 1923) With Osorio introduced the term piedra and described clinical aspects of black piedra (1876) Proposed the term bufin for active principle of frog poison (1871) Proposed that the diet could be detected in dead body due to reaction between blood and sulphuric acid in Estudios medico-legales relativos a la identidad. Anales Acad. Med. Medellin 3(11):322-39, 1891 Aided in production of Dictionnaire Encyclopedique des Sciences Medicales DESCRIBED NEW SPECIES Plantae Bromelia longissima 1909 Cleome applanata 1909 Ficus minutaefolia 1909 Ficus venenata 1871 Oreodaphne oleifera 1891 Panopsis yolombo 1950 Pernettya locifolia Smilax sanguinea 1909 Tagetes apetala 1872 Pisces (1909) Astroblepus dux Chaetostoma aburrensis Chalceus flavicolis Tetragonopterus rhomboidalis Tetragonopterus sardina Trichomycterus medellinensis HONOURS Foreign Correspondant Member, Societé Anthropologique de Paris (1870) Bronze Medal, Societé Anthropologique de Paris (1872) Invited to International Congress of Botany and Horticulture, Saint Petersburg, Russia (1883) International Scientific Medal (1892) Genus Posadaea Cogniaux 1890 (Cucurbitaceae) LINKS http://biblioteca-virtual-antioquia.udea.edu.co/pdf/5/science-lpa-apa.pdf
Anastasio Pirion
François (Anastase) Pirion, French-born Chilean father and naturalist (Ambon, Morbihan 1888 – 1959) SOME BIBLIOGRAPHY Costumbres de algunos odonatos de Marga-Marga. Rev. Chil. Hist Nat. 37:78-82, 1933 Excursión a la cordillera de Tinguirica. Rev. Chil. Hist Nat. 34:170-80, 1930 Observaciones sobre 3 odonatos del Valle de Marga-Marga. Rev. Chil. Hist Nat. 32:95-7, 1928 Aves observadas em el Valle de Marga-Marga. Rev. Chil. Hist Nat. 31:102-15, 1927 With F. Jaffuel. Hymenopteres de la Vallee de Marga-Marga. Rev. Chil. Hist Nat. 30:362-83, 1926 With F. Jaffuel. Plantas fanerógamas del Valle de Marga-Marga. Rev. Chil. Hist Nat. 25:350-405, 1923 Algunas ideas de los mapuches acerca de los sismos HONORS (Diptera) Piriona Aldrich 1928 Pirionimyia Townsend 1931