José Vicente Martins Campos

José Vicente Martins Campos, Brazilian pediatric gastroenterologist (Santa Cruz das Palmeiras, São Paulo State 23 June 1923 – São Paulo 08 September 1998) Of Italian descent from maternal side Authored over 150 works DEVELOPED MEDICINES Rarical, Resprin, Hydrax &Enterocin (for Johnson&Johnson) METHODS With W. Hoenen, A. Costa & J.F. Pontes. Estudos sobre a flora intestinal. II. Técnica geral de contagem e identificação de grupos bacterianos entéricos: interpretação dos resultados. Rev. Hosp. Clin. 11:71, 1956 With R.C. de Angelis. A method of obtaining suitable specimens of autolysed small intestinal mucosa epithelium. Arq. Gastroent. 13:55-8, 1976 Estudo dinâmico do intestino delgado no processo da absorção. II. Conceituação atual e fisiopatológica da absorção entérica: classificação geral das síndromes de má absorção. Rev. Assoc. Bras. Med. 11(4):140-58, 1965 First non-European physician to be invited to European Society for Paediatric Gastroenterology and Nutrition and later Emeritus Member of this Society His father, Joaquim Martins Campos (Oliveira, Minas Gerais State c. 1895 – c.1945) Founded Laboratório Farmaceutico Martins Campos and held about 20 pharmaceutic products such as Catemenyl, Phagocytol, Agua Inglesa Martins Campos, Vermifugo Campos, Phosphoiodan & Doralgina

José Mordoh

José Mordoh, Argentine molecular biologist and oncologist (Buenos Aires 19 February 1939 – Authored 140 papers Demonstrated the fundamental role of cellular membrane in transduction of mitogenic signs  to nucleus   Demonstrated the presence of stem cells in breast cancer Established melanoma and breast cancer human cells lines for studies in vitro and in vivo such as IIB-BR-G (1991), IIB-MEL-J (1989), IIB-MEL-LES & IIB-MEL-IAN (1995) With Susan Blau. A new element in the control of DNA initiation in Escherichia coli. Proc. Natl. Acad. Sci. USA 69(10):2895-8, 1972 With A.O. Pogo & J.R. Cordero Funes. Cytophotometry of DNA in liver cell nuclei duiring postnatal growith. New aspects of DNA class cells. Exp. Cell Res. 21:482-97, 1960 With B.R. Friedlander. Synthesis of a compound soluble in organic solvents from deoxycytidine triphosphate in permeabilized normal human lymphocytes. Mol. Cell. Biochem. 16(2):177-85, 1977 With S. Leis, A.I. Bravo, O.L. Podhajcer, C. Ballaré, M. Capurro, C. Kairiyama & L. Bover. Description of a new monoclonal antibody, FC-2.15, reactive with human breast cancer and other human neoplasias. Int. J. Biol. Markers 9(3):125-34, 1994 With I.J. Tapia, M. Aris, J.M. Arriaga, P.A. Blanco et al. Development of a novel methodology for cryopreservation of melanoma cells applied to CSF470 therapeutic vaccine. Cryobiology 67(2):163-9, 2013 First to demonstrate that after irradiation a fraction of tumor cells present large lipid bodies which mainly contain high concentration of triglycerides With G.A. Pizzurro, F.P. Madorsky Rowdo, I.M. Pujol-Lereis, A.M. Copati, M.P. Roberti, J.L, Teillaud, E.M. Levy, M.M. Barrio & L Quesada Allué. High lipid content of irradiated human melanoma cells does not affect cytokine-maturated dendritic cell function. Cancer Immunol. Immunother. 62(1):3-15, 2013   Papers in top journals With M. Resnicoff, E.E. Medrano, O.L. Podhajcer, A.I. Bravo & L. Bover. Subpopulations of MCF7 cells separated by Percoll gradient centrifugation: a model to analyze the heterogeneity of human breast cancer. Proc. Natl. Acad. Sci. USA 84(20):7295-9, 1987 With S. Cabral, S. Leis, L. Bover & M. Nembrot. Dipyridamole inhibits reversion by thymidine of methotrexate effect and increases drug uptake in Sarcoma 180 cells. Proc. Natl. Acad. Sci. USA 81(10):3200-3, 1984 With B.R. Friedlander & E.E. Medrano. Synthesis of DNA in human lymphocytes: possible control mechanism. Proc. Natl. Acad. Sci. USA 71(4):1128-32, 1974 With Y. Hirota & F. Jacob. On the process of cellular division in Escherichia coli. V. Incorporation of deoxynucleoside triphosphates by DNA thermosensitive mutants of Escherichia coli also lacking DNA polymerase activity. Proc. Natl. Acad. Sci. USA 67(2):773-8, 1970 With L.F. Leloir & C.R. Krisman. In vitro synthesis of particulate glycogen. Proc. Natl. Acad. Sci. USA 53:86-91, 1965  PATENTS With O.L. Podhajcer, S.L. de Cerone & A.I. Bravo. Monoclonal antibodies reactive with tumour proliferating cells. US Patent 5753229 A (1991) With M.M. Barrio & E.M. Von Euw. Cell lines, compositions comprising them for the treatment of melanomas, procedures to prepare the compositions, and treatment methods. ARP070101502A (2007) EP08737810A (2008) PCT/IB2008/051385 (2008) CO6260100A2 (2009) WO 2008126039 patents in Australia, Canadá, Denmark, New Zealand, United States, Japan, Korea, Spain, Mexico, Russia, China & South Africa With G.A. Rabinovich, O.L. Podhajcer, L. Fainboim, M. Alvarez & N. Rubinstein. A composition, a vector and a method used in anti-tumoral therapy, and use of galectin-1 (gal-1) inhibitors in the preparation of a medicinal product for tumor cell therapy AR037550A1 (2002) With O.L. Podhajcer, M.F. Ledda, S.A. Adris, A.I. Bravo & Y. Chernajovsky. Compositions and methods for tumour therapy. EP090097A2 (1997) PCT/GB1997/003548 (1997) WO1998/029138 & EP0950097 (1999) patents in Australia and United States     

José Miguel Mendoza

José Miguel Mendoza, Philippine mycologist and food scientist (fl.1925-63) DESCRIBED FUNGI TAXA Valid Genera Limaciniopsis 1925 Scolecopeltidella 1925 Scoriadopsis 1930 Species Aithaloderma fici 1932 Amanita manilensis 1937 com Leus-Palo Anthurus brownii 1934 Asterina phaleriae 1932 Asterina plectronica 1932 Asterina plectronicaecola 1932 Asterina xylosmae 1932 Asterinella capizensis 1932 Chaetothyrium muriforme 1932 Cercospora malvastri 1941 Cercospora merremiae 1941 Cercospora operculinae 1941 Limaciniopsis rollandiae 1925  Phragmocapnias smilacina Scolecopeltidella palmarum 1925 Scoriadopsis miconiae 1930 Stomiopeltella cassiae Stomiopeltella suttoniae HONORS Mendoziopeltis Batista 1959 (Fungi)

José Mariano Mociño

José Mariano Mociño Lozada, Mexican / Spanish physician, naturalist and anthropologist (Temascaltepec, Nueva España September 1757 – Barcelona, Spain 19 May 1820) He was professor at Université de Geneve DESCRIBED PLANTAE TAXA Valid Genera Agdestis 1817 with Sessé (Phytolaccaceae) Carminatia 1838  (Asteraceae) Cerdaia 1828 with Sessé (Caryophilaceae) Enthomanthus with Sessé (Caprifoliaceae) Lepidopappus 1836 with Sessé (Asteraceae) Recchia 1817 with Sessé (Surianaceae) Trimetra 1838 (Asteraceae)  Trivolvulus 1845 with Sessé (Convolvulaceae) Species About 1400 species from Mexican and Guatemalan flora HONORS Genus Mocinnodaphne Lorea Hernandez 1995 (Lauraceae) Section Mozinna Ortega 1798 (Euphorbiaceae)

José Jesuíno Maciel

José Jesuíno Maciel, Brazilian physician (Rio de Janeiro 07 November 1881 – São Paulo 17 July 1961) With A. Carini Rangelia vitalii etiologic agent of canine rangeliosis or nambiuvu (1915) DESCRIBED PARASITE PROTOZOA   Family Pneumocystidae with Pinto & Paraguassu 1955 Genus Rangelia with Carini 1915 Species Eimeria arnaldoi 1929 & Isospora neivai 1929 with C. Pinto HONORS Macielia Travassos 1935 (Nematoda)

José Francisco de Madureira Pará

José Francisco de Madureira Pará, Brazilian pathologist (Rio de Janeiro 29 June 1915 – Rio de Janeiro 10 April 1970) ACHIEVEMENTS Described “spider” cells in hepatic atrophies, a feature found in Labrea hepatitis. This discovery was independent from studies of Colombian A. Gast-Galvis Serviço de Estudos e Pesquisas da Febre Amarela. Annual Report, Rio de Janeiro, 1945 Resumo das atividades do Serviço Nacional de Febre amarela, 1949 Developed Madureira Pará method for leptospirosis diagnosis in paraffin included material Silver impregnation of spirochaetes in tissue sections. Description of a new technic. Arch. Path. 42:649-55, 1946  A staining method for the microscopical differentiation of Councilman bodies produced by yellow fever and carbon tetrachloride poisoning. Arq. V Congr. Intern. Microbiol. 1:469-71, 1950