Vicente Dimitri
Vicente Dimitri, Italian-born Argentine neuropathologist (Trieste, Dalmatia 19 April 1885 – Buenos Aires 03 November 1955) Described encephalo-trigeminal angiomatosis or Sturge-Weber-Dimitri disease Tumor cerebral congênito (Angioma cavernoso). Rev. Assoc. Med. Arg. 36:63, 1923 Developed a new device for labyrinth tests Presentación de un nuevo aparato par alas pruebas laberinticas SOME BIBLIOGRAPHY With J. Aranovich. Disinergia cerebelar mioclonica. Estudio clinico y histopatologico. Rev. Neurol. 12:246-66, 1947 With F.M. Cia. Síndrome de Barré (piramidal deficitária) de origen traumatica. Neurobiol. 3:108, 194? As síndromes neuro-anemicas. Neurobiologia 3:196, 194? Hemiplegia alterna superior. Neurobiologia 3, 194? Forma radiculo-cordonal posterior de la enfermedad de Friedreich. Rev. Asoc. Med. Arg. XLIX:1231, 1937 With M. Victoria. Sindrome de la artéria cerebral anterior. Rev. Neurol. Bs. Aires 1:81, 1936 Manifestaciones nervosas y radiograficas de algunos angiomas. Rev. Asoc. Med. Arg. 49:1926, 1936 With M. Victoria. Zum studium der spaten Kleinihirnatrophie mit Starrheit. Zentralbl. f. d. Ges. Neurol. (1934) Degenerescencias nervosas retrogradas. La Semana Medica 39:1705, 1932 With O. Copello & J. Naim. Paralisis radicular lumbosacra postraquianestesia. La Semana Medica 8:589, 1932 Ueber einen fall Von dustonia musculorum deformans (torsions dystonie). La Semana Medica 1:428-43, 1932 Observaciones de epilepsia mioclonica familiar com estudio histopatologico. Prensa Med. Arg. 18:1229-39, 1932 Ueber einen fall sensorischer aphasie (1926) With J. Aranovich. Ependidoma de evolución pseudomielitica. Siringomielia intra e extra blastomatosa. With I. Berconsky. Estudio clinico y anatomopatologo sobre un caso de enfermedad de Wilson
Venancio Deulofeu
Venancio Deulofeu Gascons, Argentine organic chemist (Buenos Aires 01 April 1902 – Buenos Aires 04 October 1984) ACHIEVEMENTS Established that bile of Argentine snakes displayed cholic acid With several coworkers determined composition of venoms from South American toads Demonstrated the presence of adrenaline in anuran venom Developed a new type of delayed-action insulin Obtained the apocholic acid in Wieland’s laboratory Isolated stroma from urine independently from Swiss Hassler Isolated antibiotic curamycin from Streptomyces curacoi and elucidated its partial structure (1962) With Laughe isolated alkaloids saurin and sauroxine from Lycopodius sururus (1942) Elucidated structure of gamma-fagarine from Fagara coco, olivacine and guatambuine from Aspidosperma australe and tubulosine from Pogonopus tubulosus With G. Marini Bettolo characterized flavonoid glycosides from ombú (Phytolacca dioica) Characterized chlorogenic acids and related compounds from maté (Ilex paraguayensis) Isolated and characterized new natural sugar derivatives as D-curacose, curacin and curamycose Isolated equine oestrogenic hormone (1934) Discovered new structural types in plant chemistry With A. Sordelli & R. Wernicke characterized Forssman antigen as a lipidic complex associated to a carrier protein Naturaleza del antigeno heterogenetico. Rev. Asoc. Med. Arg. 37:570, 1924 Sur la nature de l’antigéne hétérogénétique. C.R. Soc. Biol. Paris 92:898, 1925 Obtained new esthers of acids Nuevos esteres de los acidos bromopropionico y bromoisobutírico. Anal.Soc.Esp.Fis.Quim. 26:315, 1928 METHODS With Gimenez modified Wohl degradation by the use of propionylated nitriles With Sordelli developed a method for preparing insuline (Sordelli-Deulofeu method) in 1923 Developed a method for dosage of cholesterol in bilis Introduced picric acid for use in insuline precipitation and solvents and pure silk for its recovery Searched for general methods for transforming one aldose in another with exclusion of one carbon atom Developed a general method for N-methylated amino acids synthesis under aromatic aldehydes condensation with creatinine (1942) Eponym of Deulofeu-Mendivelzua method Papers in Nature With R. Labriola, O.Orias, E.M. de Españes & A.C. Taquini. Fagarine, a possible substitute for quinidine. Science 102(2638):69-70, 1945 With R. Labriola & B. Berinzaghi. Structure of alpha-fagarine. Nature 162(4122):694, 1948 With J.O. Deferrari. Preparation of D-glucose dibenzamide from pentabenzoyl-D-alpha-glucose. Nature 167 (4236):42, 1951 With F. Moewus. An antagonist of the sterility hormone rutin in the green alga Chlamydomonas eugametos: ombuoside=7,4’-dimethylrutin. Nature 173 (4396):218, 1954 HONORS Houssay Prize, Organization of American States Medal from International Academy of Lutetia Doctor Honoris Causa, Université de Paris (1955)
Trupapur Antony Davis
Trupapur Antony Davis, Indian agronomist and botanist (Nagercoil, Tamil Nadu 09 February 1923 – 10 November 1989) ACHIEVEMENTS Developed a mathematical solution to the structure of the sunflower head Developed instrumentation for agricultural research A climbing device to reach the palmyra’s valuable “toddy” (1984) Climbing the coconut: new machine for climbing palms with smooth trunks. World Crops 13:20-1, 1961 With N.A. Nagaraj & K.P.V. Menon. Sap transfusion, a new device for virus transmission trials in plants (1954) With A.P. Anand & K.P.s. Menon. Injection in coconut palms for curative purposes. I. Methods of injection. Indian Coconut J. 7(2):49-60, 1954 SOME BIBLIOGRAPHY With S.S. Ghosh. Effect of rainfall on production of coconut. Ind. Coconut J. 13(5):3-7, 1982 With J.A. Milbum. Role of pressure in xylem transport of coconut and other palms. Physiol. Plant 29:415-20, 1973 Effect of foliar arrangement on fruit production in some tropical crop plants. Trop. Ecol. Org. Prod. (1972) Fibonacci numbers for palm foliar spirals. Acta Bot. Neerl. 19:249-56, 1970 Possible geo-physical influence on asymmetry in coconut and other plants (1966) Contribution to the physiology of the coconut palm (1964) With J.C. Selvaraj. Floral asymmetry in Malvaceae. 67(2):402-9, 1964 With N.G. Pillai. Exhaust of micronutrients by the coconut palm – a preliminary study. Ind. Coconut J. 16:18-9, 1963 The dependence of yield on asymmetry in coconut palms. J. Genet. 58:186-215, 1963 Clonal propagation of the coconut. World Crops 21:253-5, 1962 Vegetative propagation in the coconut. Nature 196:904-5, 1962 High root pressure in palms. Nature 192:2778, 1961 Rejuvenation of coconut palms. Coconut Res. Inst. Ceylon 12:224-8, 1958
Thamarapu Vedanta Desikachary
Thamarapu Vedanta Desikachary, Indian phycologist (Tirupati, Chittoor District, andhra Pradesh State 18 September 1919 – Melbourne, Australia 05 November 2005) DESCRIBED ALGAE GENERA Bacillariophyceae Neofragilaria 1987 with Prasad & Prema Pinnulariosigma 1989 with Raja Rao & Sridharan Spinodiscus 1986 with Ranjitha Devi Chlorophyceae Iyengariomonas 1965 Schilleriomonas 1976 Prasinophyceae Mantoniella 1972 Papenfussiomonas 1972 Cyanophyceae Camptylonemopsis 1948 Iyengariella 1953 Mastigocladopsis 1946 with Iyengar Fossil Algae Bukryella 1996 with Prema Palaeonostoc 1972 with Sastri & Venkatachala Quadrodiscus 1990 with Prema Rossiella 1958 with Maheshwari HONORS Desikacharyella Subramanian 1984 (Rhodophyceae) Desikaneis Prasad 1993 (Bacillariophyceae) Desikacharya Saraf, Dawda & Singh 2019 (Bacteria)
Sukh Dev
Sukh Dev Lala, Indian organic chemist (Chakwal, Punjab Province 17 June 1923 – 16 October 2024) Authored about 500 scientific publications and 10 books Discovered several new structural types in sesqui and diterpenoids Characterized active principles of some Ayurvedic drugs such as shatavarin I from the roots of Asparagus racemosus Obtained longifolene and carene from Indian turpentine (Pinus longifolia), the himachalenes from devadaaru and bakuchiol from baakuchi First to demonstrate that himachalenes occurring in essential oils show useful broad spectrum activity against a variety of ectoparasites Developed Guggulsterone, a plant-derived steroid used as a therapeutic and nutritional agent Isolated copaene, longicyclene, cheilanthatriol, malabaricol and atisirene Achieved structural elucidation of novel and complex secondary plant metabolites such as zerumbone, himachalenes, malabaricol, cheilanthatriol, kodocytochalasins, bakuchiol, guggulsterone and guggultetrols between others Isolated and determinated the stereostructures of new complex molecules such as himachalenes, cuparenones, kodocytochalasins and guggulsterones With U.R. Nayak discovered the longicyclene, the first tetracyclic sesquiterpene (1963) With H. Khan, A. Zaman, G.L. Chetty & A.S. Gupta discovered cheilanthatriol, the first sesterterpene with the triterpene type ring-closure (1971) Discovered bakuchiol, the first meroterpene derived from C8+C10 pathway Discovered the guggultetrols, a new class of lipids With A. Chawla obtained a new class of triterpenoids from Ailanthus malabarica (1967) Developed new products as Guggulipid (hypocholesterolemic drug) Proposed concepts as the absolute stereochemistry biogenetic rule and the rule that claims that exotic biological materials tend to produce exotic secondary metabolites Enunciated the concept of steric diversion Demonstrated the value of reestructuring abundantly available natural products into chiral molecules of economic value METHODS/INNOVATIONS Introduced chromic acid for oxidative work-up of ozonides, thiourea for reductive cleavage of olefin ozonolysis products and Titanium tetrachloride for thioacetalization First to propose organic reactions in a solid matrix Devised several methods for synthesis and characterization of non-benzenoid aromatic systems and proposed novel systems with potential aromatic character With A.S. Gupta first to introduce the use of silver nitrate-silica gel for thin-layer chromatography of olefins (1962) Heterocyclic cleavage of homoallylic alcohols Composite amine catalysis for Knoevenagel-type condensation Manufacture of dihydrojasmone Improved Lindlar catalyst for semihydrogenation of acetylenes Developed a molybdenum oxide based Raney nickel catalyst for hydrogenation of glucose to sorbitol Developed a copper-nickel-manganese catalyst for the hydrogenation of cyclohexanones to phenols With J.S. Yadav & H.P.S. Chawla. Cleavage of homoallylic alcohols, a novel fragmentation reaction. Tetrahedron Lett. 201, 1977 With M.C. Desai, C. Singh & H.P.S. Chawla. A novel method for functionalization of C-4methyl in terpenoids. A synthesis of cycloeucalanone. Tetrahedron Lett. 5047, 1979 With V.H. Kapadia, R. Seshagiri Rao & M.Y. Ansari discovered that the alkaloid colchicine could be sourced from Iphigenia stellate for commercial purposes (patented in 1971) Held about 55 patents HONOURS Ernest Guenther Award, American Chemical Society (1980) LINKS http://www.arkat-usa.org/get-file/19562/
Silvio Dessy
Silvio Dessy, Italian-born Argentine bacteriologist (Dego, Savona Province 31 May 1869 – Buenos Aires 15 July 1951) Developed Dessy vaccine, a polivalent typhoid vaccine (1903) and Denys-Dessy vaccine for tuberculosis With F.L. Grapiolo & V. Fossati. Nueva vacina contra la fiebre tifoide: notas experimentales y clinicas. Semana Med. 23:357, 1914 With R.A. Marotta introduced the treatment of actinomycosis using tuberculin His son, Jorge Dessy Moro, bacteriologist and immunologist (La Plata 1900 – ?) Developed chromobacteriostatic tests for identifying microorganisms With A. Montenegro & A. Durante. Nuevo tratamiento de la epilepsia y estados afines con isotopos radioactivos organicos. Semana Medica 3075:807-10, 1952