Carlos Eugenio Dieulefait
Carlos Eugenio Dieulefait, Argentine statistician (Buenos Aires 27 July 1901 – Rosario 03 November 1982) Developed a method for inversion of input-output matrix (1958) Contributions/bibliography Sobre una nueva introducción de los polinomios de Legendre de los de Ch. Jordan y definición de un nuevo polinomio ortogonal que cumple determinadas condiciones (1932) La determinación de la tendencia secular en las series economicas: con una formulación de nuevas tablas de funciones ortogonales que faciliten su calculo dentro del metodo de los quadrados minimos (1932) Fundamentos para una teoria general de la correlación (1933) Sobre una nueva generación de polinomios ortogonales (1933) Generalización del coeficiente de relación de correlación (1934) Sobre la representación de una función variable real en serie de funciones ortogonales (1935) Sobre la ley sinusoidal limite de Slutzky derivada de una nueva sucesión de valores probables (1942) Nuevos principios en el problema de la cuadratura mecanica (1956) HONOURS The one Latin American in Cambridge Dictionary of Statistics Honorary Member, Royal Society of Statistics of London (1957) & Société de Statistique de France (1936)
Carlos D’Andretta Jr.
Carlos D’Andretta Jr., Brazilian parasitologist and entomologist (São Paulo 1919 – São Paulo 01 May 1986) DESCRIBED DIPTERA TAXA Genus Lutzsimulium 1947 with Vulcano Species Alouattamyia riberoi 1951 with Artigas Cuterebra ribeiroi 1951 with Artigas Anisopus albipex 1958 with Lane Inaequalium travassosi 1947 with Vulcano Kelloggina cataguasi 1956 with Lane Kelloggina cherentesi 1956 with Lane Kelloggina edwardsi 1956 with Lane Kelloggina gomezi 1956 with Lane Kelloggina guaianasi 1956 with Lane Kelloggina guarani 1956 with Lane Kelloggina laemmerti 1956 with Lane Kelloggina rabelloi 1956 with Lane Kelloggina shannoni 1956 with Lane Kelloggina tamoioi 1956 with Lane Kelloggina tapuiasi 1956 with Lane Kelloggina timbira 1956 with Lane Kelloggina travassosi 1956 with Lane Kelloggina willistoni 1956 with Lane Lutzsimulium cruzi 1947 with Vulcano Mycetobia stonei 1958 with Lane Olbiogaster antillarum 1958 with Lane Olbiogaster carioca 1958 with Lane Olbiogaster chavantesii 1958 with Lane Olbiogaster guatemalteca 1958 with Lane Olbiogaster mexicana 1958 with Lane Olbiogaster panamensis 1958 with Lane Olbiogaster similans 1958 with Lane Olbiogaster surinamensis 1958 with Lane Olbiogaster tamoioi 1958 with Lane Olbiogaster texana 1958 with Lane Simulium jundiaiense 1964 with Gonzalez Simulium nogueirai 1962 with Gonzalez Simulium pintoi 1955 with Vulcano Thyrsopelma itaunense 1964 with Gonzalez Tonnoirina albicornis with Lane Tonnoirina boraceae 1958 with Lane Tonnoirina caiuasi 1958 with Lane Tonnoirina fluminensis 1958 with Lane Tonnoirina grandis 1958 with Lane Tonnoirina hyalina 1958 with Lane Tonnoirina incasica 1958 with Lane Tonnoirina tucumana 1958 with Lane Tonnoirina wygodzinskyi 1958 with Lane Others (Lepidoptera) Genus Romualdisca 1946 with Travassos Species Romualdisca dalmeidai 1946 with Travassos
Carl Peter Von Dietrich
Carl Peter Von Dietrich, Brazilian biochemist (São Paulo 23 November 1936 – São Paulo 01 February 2005) Authored about 250 original works and held about 5,000 citations ACHIEVEMENTS Developed new methodologies for the separation and analysis of glycosaminoglycans Unraveled new metabolic pathways involving glycosaminoglycans and proteoglycans Identified and determined the characteristics of glycosaminoglycans Proposed biological and pharmacological roles for glycosaminoglycans Isolated and characterized more than 20 enzymes responsible for glycosaminoglycans degradation Proposed the basic structure of heparin in With M.E. Silva & Y.M. Michelacci. Sequential degradation of heparin in Flavobacterium heparinum. Purification and properties of five enzymes involved in heparin degradation. J. Biol. Chem. 248: 6408-6846, 1973. With H.B. Nader first to show that the biological role of heparin differs from pharmacological activity With H.B. Nader first in the world to discover and prepare low molecular weight heparin (1974) Distinguished clearly heparin from heparin sulfate showing that they play different biological and pharmacological roles Proposed a new structure for heparin and heparitin sulfates Characterized the mechanism of hemorrhagic action of heparin and its prevention in surgeries (found that ATP can dislodge heparin from lesion) With H.B. Nader, H.V. Garcia Jr. & E. Buffolo proposed employing ATP as antihemorrhagic agent (1994) A model for cell-cell recognition and control of cell growth mediated by sulfated glycosaminoglycans. Braz. J. Med. Biol. Research 17:5-15, 1984 With J.R.M. Martins & H.B. Nader proposed the diagnosis of cancer via analysis of urinary glycosaminoglycans (1993) With H.B. Nader & L. Toma proposed differential diagnosis of mucopolysaccharidosis (1996) Discovered a new mucopolysaccharidosis Developed/ obtained new heparin-like and other antithrombotic drugs First to detect the presence of glycosaminoglycans in invertebrate animals Isolated and characterized enzymes from invertebrates Isolated heparin-like compounds from marine invertebrates With G.F. Medeiros & R.A.B. Castro showed that heparan sulfates and heparins perform the same functions in vertebrates and invertebrates (1999) and the widespread occurrence of heparin-like compounds in invertebrates (2000) Showed the distribution and structural characteristics of sulfated polysaccharides in algae are specific and tissue specific SYNDROMES With P.A.S. Mourão, S.A.P. Toledo & H.B. Nader. Excretion of chondroitin sulfate C with low sulfate content by patients with generalized platyspondily (brachyolmia). Biochem. Med. 2:415-23, 1973 With S.A.P. Toledo, P.A.S. Mourão, C.M.F. Cassaro, C.A. Alves, L.M. Assis & E. Mattar. Recessively inherited, late onset, spondylar dysplasia and peripheral corneal opacity with anomalies in the urinary mucopolysaccharides. A possible error of chondroitin sulfate synthesis. Amer. J. Med. Genetics 2:385-95, 1978 METHODS With W.O. Cruz, J.R. Magalhães & L. De Meis developed isolated rabbit ear method for hemostasis in vivo (1962) With W.O. Cruz developed topical scarification in rat tail for studying hemostasis in vivo (1967) With L.B. Jaques, R.E. Baillieux & L.W. Kawanagh. A microelectrophoresis method for heparin. Canad.J. Physiol. Pharmacol. 46:351-60, 1968 With S.M.C. Dietrich. Simple micromethod for the identification of acid mucopolysaccharides of mammalian origin. Anal. Biochem. 46:209-15, 1972 With P. Bianchini, H.B. Nader, H.K. Takahashi, B. Osima & A.H. Straus. Fractionation and identification of heparin and other acidic mucopolysaccharides by a new discontinuous electrophoretic method. J. Chromatography 196:455-62, 1980 With H.K. Takahashi & H.B. Nader. A method for the rapid quantitation and preparation of antithrombin III – high affinity heparin fractions. Anal. Biochem. 116:456-61, 1981 With J.R.M. Martins, C.C. Passerotti, R.M.B. Maciel, L.O. Sampaio & H.B. Nader. Practical determination of hyaluronan by a new non-competitive fluorescence-based assay on serum of normal and cirrhotic patients. Anal. Biochem. 319:65-72, 2003 Continuous sephadex gel electrophoresis fractionation of proteins and mucopolysaccharides. Anal. Biochem. 51:345-53, 1973 INVENTION With L.O. Sampaio, H.B. Nader & J.R.M. Martins a biochemical method for detection and tracking of neoplasias (1994) HONOURS Dietrich’s hyaluronidase, an enzyme from spider Loxosceles intermedia venom
Botha de Meillon
Schalk Jacobus Botha de Meillon, South African entomologist (Prieska, Cape Province 15 October 1902 – Philadelphia, USA 06 December 2000) Authored 189 papers DESCRIBED TAXA Diptera Genera & Subgenera Ankylohelea 1987 with Wirth Capehelea 1987 with Wirth Fanthamia 1939 Kolenohelea 1981 with Wirth Luciamyia 1937 Notoceratopogon 1986 with Downes Pedilohelea 1980 with Wirth Rhinohelea 1979 with Wirth Species 423 being 219 in Ceratopogonidae and 37 in Simuliidae Siphonaptera Genera Cryptopsylla 1949 Epirimia 1940 Macroscelidopsylla 1958 Species 38 Acari Species At least 2 (Echinonyssus latiscutatus 1944 & Myonyssoides spinosus 1944 both with Lavoipierre) HONORS Demeillonia Hopkins & Rothschild 1956 (Siphonaptera) Demeillonius Davidson 1980 (Diptera) Bothamia Meiswinkel 1987 (Diptera) Bothahelea Grogan & Wirth 1983 (Diptera) Subgenus Meilloniellum Rubtsov 1962 (Diptera)
Bhola Nath Dhawan
Bhola Nath Dhawan, Indian neuropharmacologist (Khairabad, Uttar Pradesh State 11 October 1932 – Authored over 400 papers, 20 books Discovered the apomorphine stereotypy in pigeon (1960) Elucidated the role of biogenic amines and opioid peptides With A. Gulati & R.C. Srimal elucidated the role of neurotransmitters in the regulation of the blood brain barrier (1986) With A. Gulati, S.K. Agarwal, R. Shukla & R.C. Srimal developed a simple procedure for transiently opening the blood brain barrier by administration of an intravenosus bolus of hypertonic saline (1985) Discovered 8 new drugs and a diagnostic kit PATENTS (70 national and international patents; incomplete list) With D.K. Dikshit, S. Singh, G.K. Patnaik & R.C. Srimal. A process for the synthesis of 4,5-substituted 2-oxo-4-oxazolidine carboxylic acids. IN178841A5 (1997) With V.J. Ram, S.K. Singh, F.A. Hussaiani, A. Shoeb, S.B. Intripathi, G.K. Patnaik, R.C. Srimal & A.P. Bhaduri. A process for the synthesis of 3,4,6,tribubstituted-2H-pyran-2-ones having hepatoprotective activity. IN178259A15 (1997) With B.S. Singh, R. Chander, S.K. Chatterjee, Y. Dwivedi et al. A process for the preparation and composition of a fraction containing picrosides I and kuktoside. EP 0571668-A1 (1993) With S.D. Sharma, K.B. Mathur, A. Raghubir, G.K. Patnaik & R.C. Srimal. A process for the synthesis of L-tyrosyl-D-alanyl-glycyl-L-N-methyl phenylalanyl-L-methionine N-substituted amines and their corresponding sulphoxide derivatives as analgesics. IN166472A19 (1990) With P.C. Jain, R.C. Srimal, N. Anand, J.N. Sharma & V.A. Rao. Derivés de la quinoleine, leur preparation et leurs utilisations therapeutiques. FR Patent 2279403-A1 (1976) With V.A. Murthi, P.C. Jain, J.N.Sharma, R.C. Srimal & N. Anand. 1-substituted 4(-B-2-quinolyethyl)piperazines and 1,2,3,4-tetrahydroquinolyl-ethyl analogues thereof. US 03983121A With A.K. Saxena, P.C. Jain, G. Singh et al. 2-substituted-1,2,3,4,6,7,12,12-A- octahydropyrazino(2’1’:6,1)pyrido(3,4-B)indoles. US Patent 3917599 (1975)
Bernhard Dawson
Bernhard Hildebrandt Dawson, US-born Argentine astronomer (Kansas City, Missouri State 21 September 1890 – 18 June 1960) Discovered Nova Puppis star or Dawson star (1942) Identified a nebula surrounding a variable star (1928) Two new variables. Astron. J. 30 (706):84, 1917 Forty-seven new double stars. Astron. J. 35(834):1478, 1924 METHODS An improved slide rule for the addition of squares. Science 104 (2688):18, 1946 A simple procedure for photographing eclipses. Pop. Astron. 41:292, 1933 A new method for calculation of binary stars orbits Un metodo abreviado de compensación (1948) Una simplificación en la determinación del tiempo y latitud HONORS D.B. Pickering Nova Medal, American Association of Variable Stars Observers Dawson lunar crater Asteroid 1829 Dawson