Dias family

Ezequiel Caetano de Campos Dias (Macaé, Rio de Janeiro State 11 May 1880 – Belo Horizonte 22 October 1922) Brother in Law of sanitarist Oswaldo Gonçalves Cruz Performed studies on microbiology and experimental medicine Described a stable antigen for complement-fixation reaction in leishmaniasis diagnosis With A.M. da Cunha. Sur la préparation d’un antigene stable pour la réaction de fixation du complement dans le leishmanioses. C.R. Soc. Biol. 129:991-3, 1938.  With A.M. Cunha proposed a serological reaction for visceral and /or cutaneous leishmaniasis in Brasil Medico 53:89-92, 1939 Described endemic adenomycosis, the ganglionar form of paracoccidioidomycosis  Adenomicose endêmica, nova moléstia humana. Rev. Med. São Paulo 17:103, 1914 Honored in genus Diasiella Travassos 1949 (Trematoda) His son Emmanuel Dias, Brazilian physician and parasitologist (Rio de Janeiro 27 July 1908 – Uberlândia, Minas Gerais State 22 October 1962) Protégé of physician Carlos Chagas Authored at least 154 works Demonstrated definitely life cycle and mode of transmission of Trypanosoma cruzi (1933) Described life cycle of Trypanosoma cruzi in Triatoma infestans and in vertebrate hosts Estudos sobre o Schizotrypanum cruzi. Mem. Inst. Oswaldo Cruz (1934) Described new vertebrate hosts  Individualized chronic Chagasic cardiopathy With F. Laranja & G. Nóbrega. Clínica e terapêutica da doença de Chagas. Mem. Inst. Oswaldo Cruz 4:473-529, 1948  With F.S. Laranja, G. Nóbrega & A. Miranda. Chagas disease. A clinical, epidemiological and pathologic study. Circulation 14:1035, 1956 Established technical basis for Chagas disease prophylaxis employing residual action insecticides independent of Romaña and Abalos (i.e. Gammexane or BHC in 1947) With J. Pellegrino. Alguns ensaios com o “Gammexane” no combate aos transmissores da doença de Chagas no Brasil. Brasil Médico 62:185-91, 1948. Perfected the xenodiagnosis technique and the culture of Triatominae in laboratory Técnica do xenodiagnóstico na moléstia de Chagas First to propose the Chagas disease transmission by blood transfusion Verified Trypanosoma cruzi transmission by digestive route in animals First to apply the model of epidemiologic surveillance for Chagas disease control With L. Freitas Filho. Introdução ao estudo biométrico dos hemoflagelados do gênero Schizotrypanum. I. Introdução, material e técnica, problemas e métodos estatísticos. Mem. Inst. Oswaldo Cruz 38(3):427-36, 1943  

Deslandes brothers

Josué Augusto Deslandes, Brazilian plant pathologist (Belo Horizonte 08 August 1902 – Lavras, Minas Gerais State 10 December 1988) Described many pathogens of plant bacterial diseases Described a new disease, chlorotic leaf spot First description of Fusarium oxysporum f.sp. ricini With S.C. Arruda. A murcha da mamoneira do Nordeste. O Biológico 6:144-8, 1940 First to report target leaf spot in Hevea spp. Observações fitopatologicas na Amazônia. Bol. Fitossanitário 1:197-244, 1944 Described the symptomatology of Sete Voltas disease Doenças da cebola. Publ. 19, Div. Defesa Sanitária Vegetal (1944) His brother, Isaías Augusto Deslandes, plant pathologist (Belo Horizonte 15 March 1905 – Juiz de Fora, Minas Gerais State 27 February 1955) Found an effective method of combating the leaf disease of quince orchards (Entomosporium maculatum) in 1940 Developed methods for controlling quince entomosporiosis

Daniel Jacob du Plessis

Daniel Jacob du Plessis, South African surgeon (Paarl, Western Cape Province 17 May 1918 – 12 September 1999) Pioneered work on the aetiology of peptic ulceration Showed the contribution of the bile reflux to the genesis of gastric ulceration Pathogenesis of gastric ulceration. Lancet 1:974-8, 1965 His books Principles of surgery: a new approach (1968) and A synopsis of surgical anatomy (1975) were used internationally  

Daniel de la Paz

Daniel de La Paz, Philippine pharmacologist (Marikina, Rizal Province 03 January 1887 – ?) Described Cannon reflex or Cannon-de la Paz syndrome With W.B. Cannon. Emotional stimulation of adrenal secretion. Am. J. Physiol. 28:64-70, 1911 With A.G. Sison found Premna odorata effective for treating bronchial asthma SOME BIBLIOGRAPHY With F. Garcia. An experimental study on the use of apomorphine to remove foreign bodies from the respiratory passages. Phil. J. Sci. 11 Sect B : 51-59, 1916 With L.A. Guerrero & A. l. Guerrero. Poisoning by Illicium religiosum Siebold. Phil. J. Sci. Sect B 11(5):203-13, 1916 On the antihelminthic property of Quisqualis indica. Trans. 4th Congress Far Eastern Assoc. Trop. Med. 2:255, 1921.

Cristina Dizeo

Cristina Gloria Dizeo de Strittmatter, Argentine plant histologist (fl.1970) DEVELOPED / MODIFIED TECHNIQUES Nueva técnica de diafanización. Bol. Soc. Arg. Bot. 15(1):126-9, 1973 Modificación de una coloración safranina-fast green. Bol. Soc. Arg. Bot. 18(3-4), 1979 Coloración con violeta de cresyl. Bol. Soc. Arg. Bot. 19(1-2):273-6, 1980 (first time to use the metachromatic staining of Cresyl Violet in plant tissues) Modificación de la tecnica de inclusión en parafina de Johansen. Dominguezia 16(1), 2000

Carlos Ribeiro Diniz

Carlos Ribeiro Diniz, Brazilian toxinologist (Luminarias, Minas Gerais State 02 February 1919 – Belo Horizonte 08 September 2002) ACHIEVEMENTS Isolated and characterized neurotoxins from spiders and scorpions venoms With J. Moura Gonçalves isolated and characterized the active compounds of venom from Tityus serrulatus such as tityustoxin    With J. Torres discovered that pre-synaptic action of venom from Tityus serrulatus is due to acetylcholine release Developed the first dosage method of bradykininogen in blood With I. F. de Carvalho & M. Rocha e Silva. A micromethod for determination of bradykininogen in blood plasma under several physiological and pathological conditions. Nature (UK) 192:1194-5, 1961. With I.F. de Carvalho. A micromethod for determination of bradykininogen under several conditions. Ann. New York Academy of Sciences 104(1):77-88, 1963.    First to obtain data about kynetic behavior of kynin-releasing enzymes With M. Mares Guia. Alguns aspectos do estudo bioquímico das cininogeninas. Rev.Assoc. Med. Minas Gerais 19:40-52, 1968.   With J. Coutinho-Netto. Properties of tityustoxin obtained by a new method of purification. Anais Acad. Bras. Ciencias 46:699, 1974. With C. Chavez-Olortegui and C.S. Lopes et al. An enzyme linked immunosorbent assay (ELISA) that discriminates between Bothrops atrox and Lachesis muta venoms. Toxicon 31(4);417-25, 1993.  With D.A.M. Araújo, M.N. Cordeiro, M. Richardson & P.S.L. Beirão. A novel class of polypeptide toxin modifies sodium current inactivation and activation in isolated skeletal muscle. Journal of Physiology 467:365, 1993.   With J.C. R. Oliveira, L.M. Silva and et al. A method for the determination of snake venoms toxicity in vitro using cell culture. In 5 Simposio da Soc. Bras. Toxin., Angra dos Reis, rio de Janeiro, 1998.   With R. A. Mafra, S.G. Figueiredo et al. Ph Tx4, a new class of toxins from Phoneutria nigriventer spider venom inhibits the glutamate uptake in rat brain synaptosomes. Brain Research 831(1-2):297-300, 1999.   Held 2 patents   OFFICES President, International Society on Toxinology (1976-7)