Enrique Cabrera
Enrique Cabrera Cosio, Mexican cardiologist (Ciudad de Mexico 15 July 1917 – Moscow 09 January 1964) Demonstrated that Einthoven triangle is not an equilateral triangle (1945) With Sodi Pallares, Vizcaíno & Soberón showed intracavitary potential in man and dog under normal conditions (1947) With Sodi Pallares enunciated the concept of endocardioelectric deductive electrocardiography First related hemodynamics to electrocardiography (1950-2) Introduced the physiologic, clinical and electrocardiographic data for systolic and diastolic overloading With J.R. Monroy Jr. Systolic and diastolic loading of the heart. I. Physiologic and clinical data. Am. J. Heart 43:661-8, 1952 With J.R. Monroy Jr. Systolic and diastolic loading of the heart. II. Electrocardiographic data. Am. J. Heart 43:669-86, 1952 Demonstrated the physiopathology of clinical auricular flutter First recognized that Q increases (in magnitude) in diastolic overloads of left ventricle and decreases in systolic ones in Diagnostic contribution of the vectocardiogram in hemodynamic overloading of the heart (1960) Authored La Teoria y pratica de la Electrocardiografia (Theory and Practice of Electrocardiography), translated into many languages such as French and Italian (1958) EPONYMY Cabrera-Friedland sign (1953) Cabrera presentation Cabrera criterion Cabrera index
Elsimar Coutinho
Elsimar Metzker Coutinho, Brazilian gynecologist (Pojuca, Bahia State 18 May 1930 – São Paulo 17 August 2020) From Portuguese and Austrian descent Authored over 350 papers and 10 books ACHIEVEMENTS First to report myoma regression followed by pregnancy (1982) Described the role of calcium and magnesium ion like secondary agents of progesterone action Described action of gestrinone in the non-surgical treatment of fibroid tumours Described the contraceptive effects of medroxiprogesterone Discovered the contraceptive effects of gossypol that lead to first male non-hormonal contraceptive pill DEVELOPED Treatment of infertilitas provoked by endometriosis and myomatosis The first contraceptive pill containing Norgestrel (1966) with J.O. de Souza The first contraceptive pill of reduced dosage The first injectable contraceptive of long action (Depo Provera) 1960s First injectable contraceptive (Ciclofem) Pills for oral and vaginal administration (Lovelle is a subcutaneous prolonged effect contraceptive vaginal pill) Subcutaneous hormonal implants with long action The first male contraceptive (gossypol based) in 1970s Drugs that stimulate pregnancy preventing premature labor and spontaneous abortion Drugs that prevent pregnancy Drugs for treatment with hormone replacement in both sex Intrauterine dispositifs like Cruz de Lorena and Cruz de Caravaca A new treatment for endometriosis employing gestrinone With J. Carlos de Souza. Controle da fertilidade com um novo progestínico obtido por síntese total. Rev. Gynec d’Obst. 6 (1966) LINKS http://www.elsimarcoutinho.com/
Eduardo Hernán Charreau
Eduardo Hernán Charreau, Argentine molecular endocrinologist (San Fernando, Buenos Aires Province 27 May 1940 – Buenos Aires 23 March 2019) Authored over 200 works Discovered novel metabolic pathways in normal and pathologic tissues First to describe some molecular insulin and prolactin induced mechanisms about steroid metabolism of Leydig and luteal cells and in accessory sexual glands Characterized the receptor for luteinizing hormone and prolactin in Leydig cells Discovered that ovary resistance syndrome is due to circulating antibodies that affect the follicle stimulating hormone Developed and characterized a prostagen induced mammary carcinogenesis model Demonstrated that prostagens can reproduce their proliferative effects through 4 molecular families regulation such as insulin like factors, heregulin, tyrosine kinase type I activity receptors and growth factors type beta First to report interaction between progestin and the signal transduction pathways HRG/ErbB in mammary cancer (1999) Explained the molecular failures of the reproductive system in experimental diabetes Performed molecular characterization of the growth promoting effects of progestin hormones on mammary carcinogenesis Showed the activity of juvenile hormone analogues on steroid biosynthesis
Eduardo Chapot-Prevost
Eduardo Chapot-Prevost, Brazilian physician and surgeon (Cantagalo, Rio de Janeiro 25 July 1864 – Rio de Janeiro 19 October 1907) From French father and Belgian mother Introduced improvements in production of agar medium plates With F. Fajardo. Nota sobre uma simplificação na confecção das placas de agar-agar ou gelose. Tecnica Bacteriol. (1894) Performed the first successful operation for separation of siamese twins in the world (1900) Designed a special operating table for Siamese twins Possibly the first use of surgical mask (1900) Idealized a process of hepatic suture employing nailing of deep points Un nouveu procédé de reséction du foie. Arch. Prov. Chir. 10:193-214, 1900 Published Chirurgie des Teratopages (1901) with a preface written by French surgeon Felix Terrier SOME BIBLIOGRAPHY Formas clinicas do puerperismo infeccioso e seu tratamento (1885) Pesquisas histológicas sobre inervação das vias biliares e extra-hepáticas (1890) A bouba e a sífilis (1892) O carbúnculo no matadouro (1900) Xifotoracopago operado (1902) Novo toracopago vivo (1905) His brother, Rodolpho Chapot-Prevost, dentist (Manaus 04 March 1870 – Rio de Janeiro 06 March 1929) Modifications sur la technique de l’anesthesie locale specialement pour les extractions dentaires. Rev. Odontol. (1900) Modificação do fórceps para extração dentária SOME BIBLIOGRAPHY Contribution a l’etude de la classification de la carie dentaire. Odontol. 2(16):365, 445, 479, 559, 1903 Dos deslocamentos uterinos (1915)
Eduardo Calleri
Eduardo M. Calleri Garmendia, Uruguayan surgeon (Fray Bentos 21 May 1901 – Durazno 21 July 1971) Invented and modified a number of operative techniques Designed many surgical instruments Identified visor sign for hepatic hydatid cyst
Eduardo Cabana
Enrique Mario Cabaña Perez, Uruguayan mathematician and statistician (Florida 02 December 1937 – Proposed extending the notion of stochastic integral and Brownian motion to separable Hilbert spaces (1966 & 1969) Generalized the Itô lemma and solved differential stochastic equations independently of Russian Daletzky (Daletzky-Cabaña integral) in 1960s Devised the immersion method With M. Wschebor. On the barrier problem for stationary Gaussian processes. Publ. Inst. Mat. Estatis. 4:123-8, 1969 Defined Brownian leaf The vibrating string forced by white noise. Z.W. Gebiet. 15:111-30, 1970 Introduced barrier problem to solutions in stochastic analysis On the barrier problem for the vibrating noise forced by white noise. Z. Wahrschein. Verw. Gebiete 22:13-24, 1972 Introduced the supremum of a two-parameter process With M. Wschebor. The two-parameter Brownian bridge: Kolmogorov inequalities and upper and lower bounds for the distribution of the maximum. Ann. Probab. 10(2):289-02, 1982 Developed a new estimator of second spectral moment of a stationary Gaussian process Estimation of the spectral moment by means of the extrema. Trab. Estad. Invest. Operativa 36:71-80, 1985 Proposed a new definition of string martingale in the plane On a Wiener martingale characterization of two parameter Wiener processes. Statis. Probab. Lett. 10(3):263-70, 1990 With his daughter A. Cabaña Nigro introduced the concept of transformed empirical processes and developed a general procedure for constructing test classes of distributive disposition with or not parameter estimation using transformed empirical processes (1994-7) Goodness of fit and comparison tests of the Kolmogorov-Smirnov type for bivariate populations. Ann. Statistics 22:1447-59, 1994 Transformed empirical processes and modified Kolmogorov-Smirnov tests for multivariate distributions. Ann. Statis. 25(6):2388-409, 1997 OTHER CONTRIBUTIONS With M. Wschebor. An estimate for the tails of the distribution of the supremum for a class of stationary multiparameter Gaussian processes. J. Appl. Probability 18:536-41, 1981 Una familia asintoticamente optima de estadisticos lineales de rangos no anticipativos. Cuad. Estad. Matem. 7(8):73-81, 1984 Affine processes: a test of isotropy based on level sets. SIAM. J. Appl. Mathematics (1987) A Gaussian process with parabolic covariances. J. Appl. Probability 28:898-02, 1991 Modified Kolmogorov-Smirnov test for isotropic distributions in the plane. Sankhya (Ind. J. Statistics) A 58:440-63, 1996 With A. Cabaña. Modified Anderson-Darling test with selective power improvement. Publ. Matem. Uruguay 9:1-13, 2001 A test for symmetry for regression models (2006) Design of continuous regression test by transforming the accumulated residues process (2006) LINKS http://www.cmat.edu.uy/~mordecki/cabana/emc-mordecki.pdf (Spanish) file:///C:/Users/gustavo/Downloads/enrique_cabaña_recibe_este_lunes_el_título_de_doctor_honoris_causa.pdf (Spanish)