Otto Guilherme Bier
Otto Guilherme Bier, Brazilian bacteriologist and immunologist (Rio de Janeiro 26 March 1906 – São Paulo 22 November 1985) From German descent Authored over 100 works ACHIEVEMENTS Performed important contributions on studies of antigen-antibody reactions and complement system With M. Siqueira found that antigen-antibody complexes can act even at the site of passive cutaneous anaphylaxis reactions evoked by unrelated antigen-antibody systems Hemorrhagic reactions at sites of passive cutaneous anaphylaxis in guinea pig after intravenous inoculation of unrelated immune complex. Proceed. Soc. Exper. Biol. Med. 107(4):779-84, 1961 With M. Siqueira & G. Biozzi observed that immunological competence develops eventually, even in bursectomized animals, albeit with a considerable delay in time Codescribed Pacheco disease in Psittacidade birds (1929) Pacheco, G., Bier, O. Epizootie chex lês perroquets du Brésil. Relations avec Le psittacose. C.R. Séance Soc. Biol. 105:109-111, 1930. Showed that Bothrops venom displayed inactivant action on fourth component of complement system Uber Komplement-inativierung durch Bothropsgift (B. jararaca). Zeitschr. F. Immunit. 11:187-94, 1932 With M. Rocha e Silva noticed that the hemolysis is inhibited by hypertonic concentrations of NaCl (1935) Demonstrated that role of histamine in the permeability of inflammation With M.Rocha e Silva. Histamine as the primary cause of the increased capillary permeability in inflammation (1939) Described serovar Salmonella butantan with Amaral, Peluffo & Biocca 1946 Described the biological role of antibodies on glomerulonephritis With H.C. Passos, O.C. Martínez & M.S Pinheiro. Studies on the nephrotoxic activity of guinea-pig gamma 1 and gamma2 antibodies. Immun. 26(2):407-16, 1974 SOME OTHER IMPORTANT WORKS With R. Binaghi, M. Akashi & E. Avelar Naves. Mechanism of anaphylactic desensitization in guinea pigs. Rev. Fr. Allergol. 9(4):246-50, 1969 With C. Stiffel, A. Perini, H.C. Passos & G. Biozzi. Role of the bursa of Fabricius and the thymus in the synthesis of opsonin type antibodies. Pathol. Biol. 16(1):67-72, 1968 With M. Rocha e Silva & M. Aronson. Histamine release by anaphylatoxin. Nature 168(4272):445-6, 1951 With N. Planet. Sur la presence d’un facteur qui augmente la permeabilité papillaire dans les extraits de peau normale. C.R. Soc. Biol. 129:65, 1938 METHODS With M.S Pinheiro & R.S. Furlanetto. Amboceptor titration as a statistically controlled assay. J. Immunol. 69(3):241-6, 1952 With M.S Pinheiro & R.S. Furlanetto. Quantitative complement fixation in syphilis as a statistically controlled assay. J. Immunol. 74:51-6, 1954 With M.S Pinheiro, M.B. Esteves & P.M.Freire. Quantitative relations in complement fixation. Amer. J. Epidem. 89(3):353-7, 1969 With M.M. Mayer, A.G. Osier & M. Heidelberger. Quantitative studies of complement fixation. I. A method. J. Immunol. 59:195, 1948 With R. Furtado & E. Cisalpino. A plate technique for the conglutinative complement fixation test. Proc. Soc. Exptl. Biol. Med. 95:335-9, 1957. With M. Siqueira & M.B. Esteves. Quantitative studies of complement fixation. I- A simplified and accurate procedure based on 50 per cent hemolytic end point. Rev. Inst. Med. Trop. São Paulo 10:199-208, 1968. A simplified formula for the production of diphtheric toxin of high potency (50Lf). Rev. Bras. Biol. 3(3):325-9, 1943 Possibilidade de uma nova technica quantitativa da reação de Wassermann baseada na ação negativa dos componentes da alexina (1935) With I. Mota, W. Dias da Silva and N. Vaz, published Imunologia Básica e Aplicada (Fundamentals of Immunology), translated into English and German languages (1973) HONORS Bieria Leão 1940 (Trematoda)
Oswaldo Baca
Oswaldo Baca Mendoza, Peruvian chemist (Cuzco 05 August 1908 – Cuzco 12 April 1962) Introduced the term binode ENUNCIATED LAWS A quantitative law about periodic law of chemical elements Law of successive formation of immediate nucleus Law of limitation of periods Law of groups Leyes geneticas de los elementos químicos (Genetic laws of the chemical elements). Nuevo sistema periódico (New periodic system) 1953 Law of electronic configurations development, that rules the rise and development of electronic systems that form peripheral configurations in atoms Ley de configuraciones electronicas (presented in 1959; published in 1965) SOME BIBLIOGRAPHY La thio semicarbazida reactivo de ions selenito y seleniato (1949) El selenio, causa de la toxicidad ocasionada por el Astragalus garbancillo Cav. (Chusque). Bol. Soc. Cient. Cuzco 9(1):56-8, 1949 El íon complejo amoniacato de plata como reactivo del íon manganoso. Anales V Congr. Sudam. Quim (1943) Un indicador de acidez y alcalinidad. Doctoral Thesis (1938) With J.A. Parera. Análisis de los colores peruanos en la epoca precolonial. Bol. Soc. Quim. Peru 2:204-6, 1936 La mecanica ondulatoria. Dissertation (1935) and Rev. Univ. Cuzco Potenciales de ionización y los radios atomicos. Rev. Univ. Cuzco 112 Aplicaciones del método del íon electron. Determinación de números de oxidación y reducción en las reacciones organicas. Rev. Univ. Cuzco
Osvaldo Boelcke & Maevia
Osvaldo Boelcke, Argentine botanist (Buenos Aires 05 November 1920 – Béccar, Buenos Aires Province 06 June 1990) DESCRIBED Genus Lithodraba 1951 (Brassicaceae) Genus Skottsbergianthus 1984 (Brassicaceae) At least 12 new plant species HONORS Boelckea Rossow 1992 (Plantaginaceae) His second wife Maevia Noemí Correa, Argentine botanist (Buenos Aires 14 February 1914 –Buenos Aires 18 April 2005) Described genus Odontorrhynchus (Orchidaceae) in 1953 and at least 16 new plant species HONORS Maeviella Rossow 1985 (Plantaginaceae)
Oscar Brunser
Oscar Brunser Tesarschu, Argentine-born Chilean pediatric gastroenterologist (Buenos Aires 24 November 1935 – From Moldavian father Authored relevant studies about jejunal mucosa in infant malnutrition-mental With A. Reid, O. Brunser, A. Maccioni & I. Contreras. Jejunal biopsies in infant malnutrition with special reference to mitotic index. Pediatrics 38:605-12, 1966 With A. Reid, O. Brunser, A. Maccioni & I. Contreras. Jejunal mucosa in infant malnutrition. Am. J. Clin. Nutr. 21:976-83, 1968 Showed that tropical sprue was an infection consequence With S. Eidelman & F.A. Klipstein. Intestinal morphology in rural Haitians. A comparison between overt tropical sprue and asymptomatic subjects. Gastroenterol. 58:665-8, 1970 First to describe striated or brush border of intestinal epithelial cell With J.H. Luft. Fine estructure of the apex of the absorptive cell from rat small intestine. J. Ultrastruct. Res. 31:291-311, 1970 Proposed requirement 170 calories for survival With C. Castillo & M. Araya. Fine structure of the small intestinal mucosa in infantile marasmic malnutrition. Gastroenterology 70:495-507, 1976 Distinguished marasmus from kwashiorkor With O. Brunser, G. Donoso, H. Flores, A. Maccioni, M. Perretta & A. Stekel. Marasmus y kwashiorkor. Dos entidades clinicas diferentes (1988) Authored one of the first papers about probiotics With M. Araya, J. Espinoza, P.R. Guesry, M.C. Secretin & I. Pacheco. Effect of an acified milk on diarrhoea and the carrier state in infants of low socio-economic stratum. Acta Paediat. Scand. 78(2):259-64, 1989 Developed a lactose-low milk With M. Araya, J. Espinoza, S. Cruchet & J.I. Pacheco. Ensayo de una leche con bajo contenido de lactosa en la realimentación de lactantes con diarrea. Rev. Chil. Pediat. 61:94-9, 1990 Showed that addition of nucleotides to milky formulations prevent diarhoeas With J. Espinoza, M. Araya, S. Cruchet & A. Gil. Effect of dietary nucleotide supplementation on diarrhoeal disease in infants. Acta Paediatrica p. 188-91, 1994 HONOURS / MEMBERSHIP Member, International Advisory Committee, International Institute for Infant Nutrition and Gastrointestinal Disease, New York, USA (1985-90)
Orlando Baiocchi
Orlando Baiocchi, Brazilian gynecologist and obstetrician (Goiás 08 April 1915 – Goiânia 06 April 1997) From Italian descent DEVELOPED A new technique for pregnancy diagnosis The method of clinical integration (1957) INVENTED MEDICAL EQUIPMENT Cold cautery Tubular speculum A rotary electric forceps for biopsy of cervical lesions (1957)
Oreste Berta
Oreste Santiago Antonio Berta, Argentine automobile engineer and designer (Rafaela, Santa Fe Province 29 September 1938 – Gained world fame for his racing cars With Jan Balder & Henrique Iwers developed a special kit for Passat alcohol-powered engines DESIGNED Engines Berta V8 Torino OHC (1973) F3 by Berta (2005) TRV6 by Berta Duratec by Berta (2006) Cars Berta BA3 Cosworth (1974) Berta LR (1970) (one of the world’s first computer-aided designed cars) Berta VW (1980) Hollywood Berta Ford (1975) Maverick Berta (1974) Torino F-5000 (with an innovative suspension)