Radovan Borojevic
Radovan Borojevic, Croatian-born Brazilian morphologist and developmental biologist (Varazdin 16 November 1940 – Established the presence of one ancestral system of totipotent stem cells in cellular differentiation in Porifera Etude experimentale de la differentiation des cellules de l’eponge au cours de son developpement. Devel. Biol. 14:130-53, 1966 Recognized as a world reference in Calcarea class described and named 7 families, 10 genera and 34 valid species of Porifera With A.N. Monteiro, S.A. Vinhas, G.B. Domont, P.A. Mourão et al. Establishment of a continuous cell line from fibrotic schistosomal granulomas in mice livers. In vitro Cell. Dev. Biol. 21(7):382-90, 1985 With S.A. Vinhas, A.N. Monteiro, G.B. Domont et al. Liver connective tissue cells isolated from human schistosomal fibrosis or alcoholic cirrhosis represent a modified phenotype of smooth muscle cells. Bio Cell. 53(3):231-8, 1985 Proposed a method for quantification of anchorage-dependent cells in culture on plane surfaces or on microcarriers With R. Margis. Quantification of attached cells in tissue culture plates and on microcarriers. Anal. Biochem. 181(2):209-11, 1989 With L.C.F. Silva & P.A.S. Mourão. Identification of a cell responsible for synthesis of sulfated-glycosaminoglycan in schistosome-induced granulomas. Int. J. Exp. Path. 71:845-56, 1991 Experimental murine schistosomiasis mansoni. Establishment of the chronic phase of the disease. Mem. Inst. Oswaldo Cruz 87(Suppl 4):171-4, 1992 First biochemical description of the proteoglycans produced by a liver connective tissue cell line derived from schistosomal granulomas With L.C. Silva & P.A. Mourão. Membrane-associated and secreted proteoglycans from a continuous cell line derived from fibrotic schistosomal granulomas. Biochim. Biophys. Acta 1138(2):133-42, 1992 With C.B. Palatnik, E.P. de Souza et al. Transmission of visceral leishmaniasis by blood transfusion in hamsters. Braz. J. Med. Biol. Res. 29(10):1311-5, 1996 With M.R. Custodio, I. Prokic, R. Steffen et al. Primmorphs generated from dissociated cells of the sponge Suberites domuncula: a model system for studies of cell proliferation and cell death. Mech. Ageing Dev. 105 (1-2):45-59, 1998 First to analyze a promoter of a sponge gene for its activity in a heterologous cell system from higher Metazoa With C.C. Coutinho, J. Seack, G. Van de Vyver & W.E. Muller. Origin of the metazoan bodyplan: characterization and functional testing of the promoter of the homeobox gene Em H-3from the freshwater sponge Ephydatia muelleri in mouse 3T3 cells. Biol. Chem. 379(10):1243-51, 1998 With L.M. Alves, C.C. Werneck, R.R.C. Martins et al. A continuous lineage of rat adenohypophysis stromal cells: characterization and effects on GH(3)B(6) prolactin-secreting cell behavior. Biol. Cell 94(7-8):519-33, 2002 First clinical trial in the world to use stem cells to regenerate heart muscle With E.C. Perin. H.F. Dohmann, S.A. Silva & A.L. Silva. Transendocardial, autologous bone marrow cell transplantation for severe chronic ischemic heart failure. Circulation 107:2294-302, 2003 Proposed the existence of cartilage-derived progenitor cells Proposed that hepatic stellate cells represent a particular cell population specialized in storage of lipi-soluble substances With C.V. Rodrigues, P. Serricella, A.B. Linhares et al. Characterization of a bovine-collagen hydroxyapatite composite scaffold for bone tissue engineering. Biomaterials 24(27):4987-97, 2003 First report of a multicellular prokaryotic organism that proliferates by dividing into two equal multicellular organisms each similar to the parent one With C.N. Keim, J.L. Martins, F. Abreu, H. Lins de Barros et al. Multicellular life cycle of magnetotactic prokaryotes. FEMS Microbiol. Lett. 240(2):203-8, 2004 First murine cholangiocyte cell line isolated from schistosomal fibrosis reported in the literature With L.B. Chiarini. C.M. Takiya & A.M. Monteiro. Long-term culture of cholangiocytes from liver fibro-granulomatous lesions. BMC Gastroenterol. 6:13, 2006 Reported the first case of intra-arterial autologous bone marrow mononuclear cell transplantation for acute ischemic stroke With M.L. Mendonça, G.R. Freitas, S.A. Silva, H.F. Dohmann et al. Safety of intra-arterial autologous bone marrow mononuclear cell transplantation for acute ischemic stroke. Arq. Bras. Cardiol. 86(1):52-5, 2006 First to describe an in vitro model of fibrosis, hypertrophy and remodeling induced by Trypanosoma cruzi in cardiomyocyte spheroids With L.R. Garzoni, D. Adesse, M.J. Soares et al. Fibrosis and hypertrophy induced by Trypanosoma cruzi in a three-dimensional cardiomyocyte culture system. J. Infect. Dis. 197(6):906-15, 2008 With L. Baptista, R.J.C. do Amaral, R. Carias et al. An alternative method for the isolation of mesenchymal stromal cells derived from lipoaspirate samples. Cytotherapy 11:706-15, 2009 With A.J. Theodoro, D. Perrone & R.B. Martucci identified hepatic stellate cells are able to store and isomerise lycopene (2009) With R.J. do Amaral, C.S. Pedrosa, M.C. Kochem, L.S. Baptista et al. isolated human nasoseptal chondrogenic cells and proposed that they maybe a possible source cartilage tissue engineering and a model for studies of chondrogenesis (2012) Proposed a 3D co-culture system where gastric epithelia and stromal cells are grown together building spherical and solid structures With C.A. Santos, L.R. Andrade, M.H. Costa et al. Gastrospheres of human gastric mucosa cells: an in vitro model of stromal and epithelial stem cell niche reconstruction. Histol. Histopathol. 31(8):879-95, 2016 BRAZILIAN PATENTS With C.B. Palatnik. Processo de obtenção, extração, purificação e distinção de fml do extrato aquoso de promastigotas de L. donovani ld1s e uso de antígeno fml e das frações extraídas e definidas na sua totalidade ou qualquer de suas subfrações para a preparação de reagentes usados em imunodiagnóstico, controle de qualidade para leishmaniose no sangue utilizado para transfusão, transplante de órgãos, acompanhamento de tratamento de leishmaniose em humanos ou animais, em vacinação ou qualquer outro tratamento visando a imunoproteção ou imunoterapia da leishmaniose em animais ou humanos PI1100173-9 B1 (1997) With C.B. Palatnik. Composição contendo frações de células de Leishmania, denominadas antígenos fml “fucose mannose ligand” ou ligante de fucose-mannose, uso do antígeno fml e de suas subfrações e componentes para as aplicações em imunodiagnóstico específico da leishmaniose visceral humana e animal para aplicações em vacinação, tratamento ou imunoterapia contra a leishmaniose visceral humana e canina. PI9302386-3 A2 (1993) HONORS His doctoral thesis was awarded by Developmental Biology Society Genus Borojevia Klautau, Azevedo, Condor-Luján, Rapp, Collins & Russo 2013 (Porifera)
Pushpa Mitra Bhargava
Pushpa Mitra Bhargava, Indian biochemist (Ajmer District, Rajasthan State 22 February 1928 – Hyderabad 01 August 2017) Authored over 125 research papers ACHIEVEMENTS First report on the identification of genus Pseudomonas from Continental Antarctica With S. Shivaji, N. Shyamala Rao, L. Saisree, V. Sheth & G.S.N. Reddy. Isolation and identification of Pseudomonas spp. from Schirmacher Oasis, Antarctica. Appl. Environ. Microb. 55:767-70, 1989 With V.N. Rao. Isolation, characterisation and possible mode of action of antiseminalplasmin, a new protein that inhibits the antimicrobial activity of seminalplasmin. Biochem. J. 227:609-19, 1985 Four new and unusual proteins from bovine seminal plasma. Biochem. Soc. Trans. 9:540-3, 1981 Discovered semilplasmin or caltrin With E.S.P. Reddy. Seminalplasmin: an antimicrobial protein from bovine seminal plasma which acts in E. coli by specific inhibition of rRNA synthesis. Nature 279:725-8, 1979 Regulation of cell division and malignant transformation. A new mode of control by uptake of nutrients. J. Theor. Biol. 68:103-37, 1977 With T. Pallaiah & E. Premkumar. Aminoacyl-transfer RNA synthetase recognition code-words in yeast transfer RNAs: a proposal. J. Theor. Biol. 29:447-69, 1970 Showed a new type of RNA in extracellular zone of normal tissues (1960s) Co-discovered the anticancer drug 5-fluorouracil With C. Heidelberger, K.C. Leibman & E. Harbers. The comparative utilization of uracil-2-C14 by liver intestinal mucosa and Flexner-Jobling carcinoma in the rat. Cancer Research 17(5):399-404, 1957 With C. Heidelberger discovered the nature of chemical bond between carcinogen and tissue proteins (1955-6) METHODS With S. Shankarnarayan, C.B.S. Dutt, S. Shivaji & R. Manchanda. A cryosampler payload for aseptic air sample collections at stratospheric altitudes using balloons (2006) Developed a simple computer program to locate repeating subsequences of all possible lengths in a given nucleic acid With M.W. Panditr, A. S. Kolaskar & T.A. Thanaraj. Analysis of repeating oligonucleotide sequences in ribonucleic acids using an Apple II microcomputer (1986) With S.T. Jacob. A new method for the preparation of liver cells in suspension. Exper. Cell Research 27:453-67, 1962 With S.H. Zaheer. A new synthesis of some derivatives of 4,4′-stilbenediol. Nature 171:746-7, 1953 OTHER CONTRIBUTIONS Discovered 9 new bacterial species from Antarctic Continent and stratosphere With K.H. Scheit & E.S.P. Reddy. Seminal plasmin is a potent inhibitor of E. coli RNA polymerase in vitro. Nature 279:728-31, 1979 Incorporation of radioactive aminoacids into the proteins of bull spermatozoa. Nature 179:1120-1, 1957 HONORS Bhargavaea Shivaji, Manorama, Pindi & Reddy 2009 (Bacteria) LINKS www.pmbhargava.com
Pio Buck
Pio Buck, Swiss-born Brazilian jesuit and amateur entomologist (Hochdorf, Lucerne Canton 22 July 1883 – Porto Alegre 21 August 1972) HONORS (Coleoptera) Buckelater Costa 1993 Buckia Cobos 1956 Buckibrotica Bechyné & Bechyné 1969 Piobuckia Bechyné 1956
Pierre Joseph Auguste Bravard
Pierre Joseph Auguste Bravard, French/Argentine paleontologist and cartographer (Issoire, Puy de Dome 18 June 1803 – 28 March 1861) Introduced new concepts in the field of taphonomy SOME BIBLIOGRAPHY Catalogue des especes d’animaux fosiles recueillies dans l’Amerique du Sud de 1852 a 1860 (1860) Monografia de los terrenos marinos terciarios de las cercanias del Paraná (1858) Observaciones geologicas sobre diferentes terrenos de transporte en la hoya del Plata (1857) Geologia de las pampas (1857) Mapa geologico y topografico de los alrededores de Bahia Blanca (1857) DESCRIBED FOSSIL MAMMALIAN GENERA Arctotherium 1857 Budomys 1843 Cainotherium 1857 Camelotherium 1857 Cardiodus 1857 Cynodictis 1850 with Pomel Eutemnodus 1858 Neomys 1843 Opistorhinus 1857 Platyodon 1853 Plesiarctomys 1852 HONORS Bravardia Hauthal 1902 (Fossil Plantae)
Pedro Joaquin Bermudez
Pedro Joaquín Bermudez Hernandez, Cuban / Venezuelan micropaleontologist and malacologist (Vega Alta, Las Villas Province 24 February 1905 – Caracas 03 September 1979) DESCRIBED / NAMED NEW TAXA Living Mollusca Species / Subspecies With Torre Cerion cuspidatum Cerion dickersoni Cerion filiale Cerion guajabensis Cerion kemperi Cerion macrodon Cerion minae Cerion minae enriquis Cerion romanoensis Cerion sanctamariae Cerion scopulorum Cerion sifontesi Cerion versatile Cysticopsis puncticulata Opisthosiphon delectum scopulorum Urocoptis aguadensis Urocoptis asinorum Urocoptis camagueyana 1938 Urocoptis cardenensis Urocoptis cleti Urocoptis concolor Urocoptis costellaris Urocoptis costellaris purioensis Urocoptis delectabilis eudasta Urocoptis depressicostata Urocoptis fortiuscula Urocoptis guajenensis Urocoptis heteosculpta michaelis Urocoptis jovae Urocoptis laeviuscula Urocoptis obscura Urocoptis oleacea 1972 Urocoptis palmeri Urocoptis proteus margidula Urocoptis proteus turgens Urocoptis recticostata fuscula Urocoptis rosaperdida Urocoptis rufescens Urocoptis vermicularis Urocoptis yaguajayensis Alone Urocoptis aguayoi Urocoptis lemondi scopulorum Urocoptis michaeli Fossil Foraminifera Genera Acervoschwagerina 1949 Acostina 1949 Aguayoina 1939 Alvarezina 1963 with Rivero Asteriginata 1949 Asteriginita 1966 with Seiglie Asteriginoides 1952 Asterotrochammina 1963 with Seiglie Barbourinella 1940 Biasterigerina 1965 with Seiglie Boreloides 1947 with Cole Bronnimannia 1952 Camagueyia 1944 with Cole Caribeanella 1952 Charltonina 1952 Chitinosiphon 1954 with Thalmann Civrieuxia 1978 Claudiostriatella 1965 with Seiglie Colomia 1948 with Cushman Compressigerina 1949 Conglophragmium 1963 with Rivero Corrugatella 1965 with Seiglie Cribrogloborotalia 1936 with Cushman Cribropyrgo 1946 with Cushman Cuneolina 1941 with Cushman Cushmanella 1936 with Palmer Cylindroclavulina 1952 with Key Dusenburyina 1952 with Key Eoannularia 1944 with Cole Eoconuloides 1944 with Cole Eodictyoconus 1944 with Cole Falsoplanulina 1979 Ginesina 1952 with Key Glabratellina 1965 with Seiglie Glaucoammina 1969 with Seiglie Hemigypsina 1952 Heminwayina 1951 Heronallenita 1965 with Seiglie Hofkerinella 1952 Hopkinsinella 1966 with Fuenmayor Lamellodiscorbis 1952 Longiapertina 1966 with Seiglie Neocarpenteria 1936 with Cushman Neocuneolina 1963 with Rivero Neoglabratella 1965 with Seiglie Neogyroidina 1949 Neopateoris 1963 with Seiglie Neorotalia 1952 Olssonina 1949 Palmerinella 1934 Pannellaina 1976 with Seiglie Pavoninoides 1949 Pileolina 1952 Pinaria 1937 Planispirillina 1952 Planodiscorbis 1952 Planoglabratella 1965 with Seiglie Planogypsina 1952 Praeglobotruncana 1952 Pseudorbitolina with Cushman Rectoeponides 1935 with Cushman Reichelinella 1966 with Seiglie Riveroina 1939 Riveroinella 1967 with Seiglie Rolshausenia 1952 Sporohantkenina 1937 Stichocibicides 1936 with Cushman Strebloides 1963 with Seiglie Thalmannita 1952 Truncorotalia 1949 with Cushman Truncorotaloides 1953 with Bronnimann Turborotalia 1949 with Cushman Species 263 HONORS Mollusca Bermudezia Torre & Bartsch 1941 Bermudezisphonia Torre & Bartsch 1941 Bermudezicoptis Jaume & Torre 1972 Fossil Foraminifera Bermudezina Cushman 1937 Bermudezella Thalmann 1951 Bermudezinella Sellier de Civrieux 1969 Bermudezita Seiglie 1961 Relevant Source Geos 25:68-73, 1979 (in Spanish; contains bibliography) His nephew, Gustavo Fidel Furrazola Bermudez, Cuban geologist and micropaleontologist (Vega Alta, Villa Clara Province 24 April 1935 – La Habana 05 May 2010) DESCRIBED NEW FOSSIL TAXA Genus Cubanites 1965 Species Bermudeziella bermudezi 1965 Chitinoidella lubimovae 1973 with Kreisel Chitinoidella pinarensis 1973 with Kreisel Discoaster circularis 1972 with Kreisel Discoaster cubensis 1967 with Iturralde Vinent Discoaster subdeflandrei 1967 with Iturralde Vinent Discoaster triguarensis 1967 with Iturralde Vinent Dobeniella cubensis 1965 Furrazolaia cristobalensis 1965 With Chudoley /Judoley (1968) Genera Cubasphinctes Pseudoanahamulina Species / Subspecies Cubaochetoceras brevicostatum Cubaochetoceras submexicanum Cubaochetoceras subvignalensis Cubasphinctes jaworskii Haploceras cubensis Ochetoceras (Cubaochetoceras) diversicostatum Ochetoceras (Cubaochetoceras) mexicanum cubensis Perisphinctes (Arisphinctes) albeari Perisphinctes (Arisphinctes) albeari ampliumbilicatus Perisphinctes (Arisphinctes) guanensis multicostatus Perisphinctes (Arisphinctes) humboldti Perisphinctes (Cubanensis) intermedius Perisphinctes (Arisphinctes) poeyi Perisphinctes (Subdiscophinctes) acandai Perisphinctes (Subdiscophinctes) pichardoi Perisphinctes (Subvinalesphinctes) corrali Perisphinctes guanensis anguistiumbilicatus Salinites bicostatum Salinites gallardoi Subplanites cubensis Vinalesphinctes (Subvinalesphinctes) bermudezi Vinalesphinctes (Vinalesphinctes) parvicostatus Vinalesphinctes (Vinalesphinctes) sagrai Vinalesphinctes (Vinalesphinctes) subniger Vinalesphinctes (Vinalesphinctes) subroigi Virgatosphinctes pinarensis HONORS (Fossil Protozoa) Bermudeziella Benzaggagh 2020 Furrazolaia Benzaggagh 2020
Pedro Belou
Pedro O. Belou, Uruguayan-born Argentine anatomist and surgeon (Minas, Uruguay 19 February 1884 – Buenos Aires 06 September 1954) Son of French immigrants ACHIEVEMENTS Published more than 200 scientific works Performed studies about human ear, biliary system and vasculature. Gold Medal laureate, Medical Section of International Fair of California (1918) for his studies about ear’s anatomy Published Atlas Anatomico del organo de oído y de las regiones con el vinculadas (1923), being laureated with Testut Prize from Academie de Medicine de Paris in 1931 Presented Atlas Estereoscopico de la Anatomía de las Arterias (1928-34) received highly by anatomical authorities in Europe and USA. Developed a diaphanization method