Javier Angelo Arías-Stella, Peruvian pathologist (Lima 02 August 1924 – Lima 25 February 2020)

Authored over 150 publications on general, surgical and gynecological pathology and on the biology and pathology at high altitudes

Described Arias Stella phenomenon, reaction or effect and Arias Stella cells

Atypical endometrial changes associated with the presence of chorionic tissue. Arch. Pathol. 58:112-8, 1954 

With Dante Peñaloza presented the concept that sustained hypoxia could induce anatomic narrowing of the pulmonary arteries distinguishing from acute hypoxic vasoconstriction (1962)

With D. Peñaloza demonstrated that was persistent ventricular hypertrophy in high-altitude dwellers from the postnatal period to adulthood in 6 papers (1957-71)

Described the mechanism of chronic hypoxia-induced pulmonar hypertension and the persistence of thick distal pulmonar arteries

With M. Saldaña. The terminal portion of the pulmonary arterial tree in people native to high altitudes. Circulation 28:915-25, 1963

With D. Peñaloza, F. Sime, S. Recavarren & E. Marticorena. The heart and pulmonar circulation in children at high altitudes: physiological, anatomical and clinical observations. Pediatrics 34:568-82, 1964

With D. Peñaloza. The heart and pulmonar circulation at high altitudes healthy highlanders and chronic mountain sickness. Circulation 115:1132-46, 2007

Papers with more 100 citations

With D. Peñaloza. The heart and pulmonar circulation at high altitudes healthy highlanders and chronic mountain sickness. Circulation 115:1132-46, 2007

With P.H. Lieberman, R.A. Erlandson & J. Arias-Stella Jr. Histology, immunohistochemistry and ultrastructure of the verruga in Carrión’s disease. Am. J. Surg. Pathol. 10(9):595-610, 1986

With J. Valcarcel. Chief cell hyperplasia in the human carotid body at high altitudes: physiologic and pathologic significance. Human Pathol. 7(4):361-73, 1976

With C. Edwards, D. Heath, P. Harris, Y. Castillo & H. Krüger. The carotid body in animal sat high altitude. J. Pathol. 104(4):231-8, 1971

With H. Krüger. The placenta and the newborn infant at high altitudes. Am. J. Obst. Gynec. 106(4):586-91, 1970 

With D. Peñaloza, F. Sime, S. Recavarren & E. Marticorena. The heart and pulmonar circulation in children at high altitudes: physiological, anatomical and clinical observations. Pediatrics 34:568-82, 1964

With M. Saldaña. The terminal portion of the pulmonary arterial tree in people native to high altitudes. Circulation 28:915-25, 1963

Papers in top journals

With D. Peñaloza. The heart and pulmonar circulation at high altitudes healthy highlanders and chronic mountain sickness. Circulation 115:1132-46, 2007

With D. Peñaloza, F. Sime, S. Recavarren & E. Marticorena. The heart and pulmonar circulation in children at high altitudes: physiological, anatomical and clinical observations. Pediatrics 34:568-82, 1964

With M. Saldaña. The terminal portion of the pulmonary arterial tree in people native to high altitudes. Circulation 28:915-25, 1963

With M. Saldaña. Studies on the structure of the pulmonary trunk.III. The thickness of the media of the pulmonary trunk and ascending aorta in high altitude natives. Circulation 27(6), 1963

With M. Saldaña. Studies on the structure of the pulmonary trunk.II. The Evolution of the elastic configuration of the pulmonary trunk in people native to high altitudes. Circulation 27(6), 1963

With M. Saldaña. Studies on the structure of the pulmonary trunk. I. Normal changes in the elastic configuration of the human pulmonary trunk at diferente ages. Circulation 27(6), 1963

With S. Recavarren. Topography of right ventricular hypertrophy in children native to high altitude. Am. J. Pathol. 41(4):467-75, 1962

With S. Recavarren. Right ventricular hypertrophy in native children living at high altitude. Am. J. Pathol. 41(1):55-64, 1962

With R. Mellors, M. Siegel & D. Pressman. Analytical pathology. II. Histopathologic demonstration of glomerular-localizing antibodies in experimental glomerulonephritis. Am.J. Pathol. 31(4):687-715, 1955 

HONOURS

Robert F. Grover Award, American Thoracic Society (2008) for his studies on cardiovascular conditions at high altitudes