Biography
Plutarco Floresmilo Naranjo Vargas, Ecuadorian allergologist and pharmacologist (Ambato 18 June 1921- Quito 27 April 2012)
Authored 300 papers ou monographs and 94 books and leaflets
Demonstrated that plants death during hoar-frost is due to changes in pH towards acidity with clotting of intracellular coloids
Necrosis fría de las plantas (1947)
Demonstrated that three antihistaminic substances association presented a synergic effect with decreasing of side effects. This paved a way towards a drug named Hista3 launched in the market with international success
With E. Banda de Naranjo. Studies of the combined action of some antihistaminic agents. Ann. Allergy 11(6):699-716, 1953
Proposed dissolve penicillin in a pectin colloid to extend its effects (18 to 24 hours). This product was registered as Radualina
SOME BIBLIOGRAPHY
El sistema neurovegetativo
Timo, Inmunición y Alergia (1965)
Farmacologia: reacciones indeseables por drogas (1969)
La Etnomedicina em el Ecuador y la Medicina Tradicional Aborigen
With E. Banda de Naranjo. Inactivation of the antihistaminic drugs in the liver and in the gastrointestinal tract. J. Allergy 24(5):442-5, 1953
Nialamide as a coadjuvant in the treatment of allergic eczema. Rev. Med. Hosp. Gen. 41:193-7, 1961
Toxicity of histamine: lethal doses. Handbook Exp. Pharmacol. 18(1):179-201, 1966
HONOURS
President, 43th World Health Assembly (1991)
