Biography
Plutarco Floresmilo Naranjo Vargas, Ecuadorian allergologist and pharmacologist (Ambato 18 June 1921- Quito 27 April 2012)
Authored 300 papers ou monographs and 94 books and leaflets
Demonstrated that plants death during hoar-frost is due to changes in pH towards acidity with clotting of intracellular coloids
Demonstrated that three antihistaminic substances association presented a synergic effect with decreasing of side effects. This paved a way towards a drug named Hista3
Suggested incorporate penicillin to a pectin colloid solution that became Radualine
SOME BIBLIOGRAPHY
El sistema neurovegetativo
Timo, Inmunición y Alergia (1965)
Farmacologia: reacciones indeseables por drogas (1969)
La Etnomedicina em el Ecuador y la Medicina Tradicional Aborigen
Necrosis fría de las plantas (1947)
With E. Banda de Naranjo. Inactivation of the antihistaminic drugs in the liver and in the gastrointestinal tract. J. Allergy 24(5):442-5, 1953
Toxicity of histamine: lethal doses. Handbook Exp. Pharmacol. 18(1):179-201, 1966