Antonino dos Santos Rocha
Antonino dos Santos Rocha, Portuguese-born Brazilian nephrologist (Portugal 06 November 1936 – São Paulo 19 October 1990) Internationally recognized as an authority on renal physiology and physiopathology A number of his works were considered international classics in the field Discovered chloride channel on the Henle loop ascending limb Proposed a new model of countercurrent system With J.P. Kokko, F.C. Rector Jr & M. Imai. Experimental and theoretical evidence for the passive equilibration model of countercurrent multiplication system. Proc. 5th Intern. Congr. Nephrol. 2:91-6, 1972 Performed the first direct experiments on the thick ascending limb of Henle’s loop and discovered that transepithelial potential difference across it is oriented lumen positive independently of Maurice B. Burg & Nordica Green With J.P. Kokko. Sodium, chloride and water transport in the medullary thick ascending limb of Henle. Evidence of active chloride transport. J. Clin. Invest. 52:612, 1973 First work employing micropuncture in the functional study of glomerulopathies With M.M. Machado & G. Malnic. Micropuncture study in rats with experimental glomerulo-nephrites. Kidney Intern. 3(1):14, 1973 Described the K transport mechanism in this nephron segment and a process of K medullary re-circulation With J.P. Kokko. Membrane characteristics regulating potassium transport out of the isolated perfused descending limb of Henle. Kidney Intern. 4:326-30, 1973 Clarified the mechanism of urea intrarenal re-circulation and the process by which the medullary nephron becomes hypertonics With J.P. Kokko. Permeability of medullary nephron segments to urea and water. Effect of vasopressin. Kidney Intern. 6:379-87, 1974 With S. Tsuzuki, O.M. Gomes, N. Gushi, J.B. Magaldi & G. Verginelli. Bomba para infusão venosa contínua com baixo fluxo. Novo modelo (1974) Analysed the calcium and phosphate transport in each segment of Henle loop With J.B. Magaldi & J.P.Kokko. Calcium and phosphate transport in isolated segments of rabbit Henle’s loop. J. Clin. Invest. 59:875-93, 1977 Showed that papillary collecting duct plays a role in regulating the urinary excretion of chlorine and sodium ions and in maintenance of extracellular volume With Lucia H. Kudo. Sodium chloride and electrical gradient across the isolated perfused papillary collecting duct. Anais 8th Internat. Congr. Nephrol. C5 (1978) First to use rat as experimental model in microperfusion laboratory With A.L.J. Almeida. Características funcionais da alça de Henle e ducto coletor do rato recém-nascido: estudo de microperfusão “in vitro”. Doctoral Thesis, Instituto de Ciencias Biomédicas, Universidade de São Paulo (1979) Showed diferences between papillary collecting duct and cortical tubule in relation to sodium and potassium transport and physiological and physiopathological roles Heterogeneidade functional do ducto coletor: transporte de sódio e cloro. Efeito do lítio sobre a permeabilidade da agua. Thesis, Faculdade de Medicina, Universidade de São Paulo (1979) Showed that biggest part of filtrate calcium is reabsorbed in pars recta of proximal tubules and that this reabsorption occurs by a distinct mechanism in the upper portions of proximal tubules With A.L.J. Almeida & L.H. Kudo. Calcium transport in isolated perfused pars recta of proximal tubule. Braz. J. Med. Biol. Res. 14:43-9, 1981 Authored the first work dealing about the features of water and urea transport in human nephron segments With L.H. Kudo. Water, urea, sodium, chloride and potassium transport in the “in vitro” isolated perfused papillary collecting duct. Kidney Internat. 22:485, 1982 First to show a model of in vitro cultured papillary collecting duct cells from rat kidneys With M. Ori. Cultura primária de células do ducto coletor papilar: transporte de sódio e incorporação de timidina (1984) Other works with good repercussion With L.H. Kudo. Chloride and sodium secretion by rat papillary collecting duct. Permeability of medullary nephron segments to urea and water. Effect of vasopressin. Kidney International 6:379, 1974 With J.B. Magaldi. Calcium and phosphate transport in isolated segments of rabbit’s Henle loop. J. Clin. Invest. 59:975, 1977 With M.I.P. Leão, C.M.B. Helou, R. Costa & J.B. Magaldi. Mecanismo de espoliação de potássio produzida pela furosemida. Rev. Bras. Pesq. Med. Biol. 12(6):391-9, 1979
Annamalai Ramanathan
Annamalai Ramanathan, Indian mathematician (Madras 29 August 1946 – Chicago 12 March 1993) Gave a notion of stability for principal G-bundle on a Riemann surface Constructed a moduli space for semistable principal bundles with a real reductive structure group With S. Ramanan proved that the tensor product of a semistable vector bundles is semistable (1984) With V.B. Mehta introduced the notion of a Frobenius split variety and compatibly split subvarieties (1985) Proved that a principal G-bundle admits an Einstein-Hermitian connection if and only if it is polystable (1988) EPONYMY Ramanan-Ramanathan theorem Rumford-Mehta-Ramanathan restriction theorem Raghunathan-Ramanathan theorem Kumar-Narasimhan-Ramanathan lemma Ramanathan lemma Ramanathan stability Mehta-Ramanathan theorem for linear systems Mehta-Ramanathan theorem for slope K-semistability Mehta-Ramanathan theorem rank of a real form
Anjali Roy
Anjali Roy, Indian mycologist (fl.1961-98) SOME BIBLIOGRAPHY With A.B. De. Taxonomy of Hexagonia scutellata comb. nov. J. Mycopath. Research (1998) With A.B. De. New records of Polyporaceae from India (1997) With A.B. De. Polyporaceae of India (1996) With B. Bhattacharjee & A.L. Majumder. Beta-glucosidase of a white-rot fungus Trametes gibbosa. Biochem. Internat. 28(5), 1992 With A. Mitra & S. Dutta. New records of two wood rotting fungi from India. Indian Forester 11(2): 1985 With M.S. Singh. Studies on human pathogenic fungi from soil (1984-5) With A. Pal & A.B. De. Nuclear behavior in basidia of Polyporus antihelminthicus Berk. Nova Hedwigia 36, Studies on the Indian polypores. VI. Morphological and cultural characters of Irpex flavus Klotzsch. Nova Hedwigia 34:259-63, 1981 Taxonomy of Fomes durissimus. Mycologia 71:1005-8, 1979 Structures of zones in fruiting bodies of Polyporaceae. Nova Hedwigia 27:801-4, 1976 Record of Poria xylostromatoides from India (1973) Some microstructures in relation to Polyporaceae. Mycopath. Mycol. Applicata 48:111-9, 1972 A significant variation of Microsporon gypseum. Mycopathol. 37:45-8, 1969 Anatomy of Indian Polyporaceae. Bull. Bot. Soc. Bengal 22, 1968 Studies on hyperpigmented form of Trichophyton rubrum (1964) With A. Mitra. Taxonomy of Daedalea flavida Lev. HONORS Royoporus A.B. De 1996 (Fungi)
Angel Roffo
Angel Honorio Roffo Gazzo, Argentine oncologist (Buenos Aires 30 December 1882 – Buenos Aires 24 July 1947) Performed over 400 studies about cancer and authored 6 books ACHIEVEMENTS Performed the first studies about action spectrum of skin photocarcinogenesis (1939) Showed that cholesterol is found in all malignant tumors of the skin and it is susceptible to the influence of solar radiations Developed a stable compound with selenium, rubidium and eosine for cancer treatment Developed a “culture box” for sterilization in autoclave Recognized tobacco as most significant cause of lung cancer Realized that the tar in cigarettes was primarily cancer responsible His discoveries about tobacco as agent of cancer were forgotten and rediscovered by European and US researchers a few decades later Tobacco as a carcinogenic agent. Amer. J. Cancer 32:294, 1938 Unidad cancerígena de los alquitranes de diversos tipos de tobacos. Bol. Inst. Med. Exper. Estud. Trat. Cancer 15:349-406, 1938 Described Roffo sarcoma Sarcoma fusocelular del estomago. Bol. Inst. Med. Exper. Estud. Trat. Cancer (1937) Identified polycyclic aromatic hydrocarbons as the principal carcinogenic agents in tobacco Discovered benzopyrene in tobacco /cigarette Krebsserzeugendes Benzpyren gewonnen aus Tabakteer. Zeitschr. f. Krebsforschung 49:588, 1939 Suggested a relationship between skin cancer and overexposure to the Sun Krebs und Sarcom durch Ultraviolett und Sonnenstrahlen. Zeitschrift fur Krebsforschung 41:448-67, 1935 Described and named nodular myolisis Miolisis nodular de la lengua. Prensa Med. Arg. 15:78-81, 1928-9 Developed Roffo neutral red reaction or test for cancer diagnosis With R. Rivarola. Reacción del rojo neutro en el cancer: su valor diagnostico. Bol. Inst. Med. Exper. Estudo Trat. Cancer 2:709-716, 1925 Le rouge neutre comme indicateur dans les processus d’autolyse des tissus normaux et pathologiques. Les Neóplasmes 3 (1926) Described Roffo biological reaction of spleen La reacción biologica del bazo en el cancer provocado por la sangre humana de cancerosos. Bol. Inst. Med. Exper. Est. Trat. Cancer 10:745-56, 1933 Contributions Existencia en la sangre y en la orina de cancerosos y embarazadas de un principio activo de crecimiento esplénico. Bol. Inst. Med. Exper. Estud. Trat. Cancer 17:415-58, 1940 With A.E. Roffo. Resinificación del colesterol: nuevo derivado del colesterol (1939) With L.M. Correa. La neoreacción de Botelho, segundo nueva técnica. Bol. Inst. Med. Exper. Bs Aires 18:49-54, 1928 With L.M. Correa. On the presence of insulinoid in malignant tumor. J. Cancer Res. 11(1):126, 1927 La sobrevida de los tejidos después de la muerte del sujeto. Su comprobación hasta veintitos diaz. Bol. Inst. Med. Exper. 3:118-75, 1927 With J.B. Rivarola. A refractometric property of the blood câncer patients, and its diagnostic value. Bol. Inst. Med. Exper. 1:68, 1925 Nuevo tumor transmisible en la rata blanca. Prensa Med. Argent. (1917) With H. de Giorgi. Modification du milieu pour la croissance du tissu normal et du tissu neoplasique With L.M. Correa. Sur une reaction chimique des rayons de Roentgen. Rev. Sud Amer. Books (some) Esteridos y cancer: estudio biológico, físico y químico (1942) With J. Thomas. La chimie du cancer (1933) Biologia del cancer (1925) Papers in Lancet Role of the ultra-violet rays in the development of cancer provoked by the sun. The Lancet 1:472-4, 1936 The photoactive function of cholesterol in skin câncer. The Lancet 2:1187, 1931 Comparative Oncology Sobre un tumor paradentario en la corvina. Bol. Inst. Med. Exper. 2:28-42, 1925 Le sarcome des poissons. Neoplasmes 3:231-4, 1924 El câncer en los animales domesticos en la Argentina. Rev. Inst. Bacteriol. 1(3):333-40, 1918 HONORS Guido Banti Prize, Universitá di Firenze (1936) Gold medal, International Exposition of Panamá (1915) Gran Prix, International Exposition of Brazil (1922) Prix Berraute, Academie de Medecine de Paris Prix Amerongen, Ligue Française contre le Cancer (1939) President, Société Internationale de Recherches contre la Tuberculose et le Cancer de Paris (1930-2) Honorary Member, First International Congress of ElectroRadiobology, Veneza, Italy (1934) President, Committee for Cancerology Studies, IV International Hospital Association Congress, Toronto (1939) Gold Medal & Honor Diplome, International Congress of Hygiene, Rome (1912) Medicine & Physiology Nobel Prize nominee (1927, 1937 & 1940) His son, Angel Eduardo Roffo Larroque, oncologist and biophysicist (Buenos Aires 14 July 1909 – La Lucila, Buenos Aires Province 09 September 1985) ACHIEVEMENTS A new technique for determination of fluorescence Nueva tecnica de la determinación de la fluorescencia en el Instituto de Medicina Experimental. Bol. Inst. Med. Exper. Estudo Trat. Cancer 58:975, 1941 A new filter for photo-fluorescence Un Nuevo filtro para la fotofluorescencia. Bol. Inst. Med. Exper. Estudo Trat. Cancer 59: 93, 1942 A new method of calculating the dosage of radium Nueva regla de calculo para mediciones em la radiumtherapia. Bol. Inst. Med. Exper. Estudo Trat. Cancer 59: 83-92, 1942 New technique for quantitative dosage of ultraviolet radiations Nueva tecnica para la dosificación cuantitativa de las radiaciones ultraviolet en la practica del uso medico. Bol. Inst. Med. Exper. Estudo Trat. Cancer
André Pinto Rebouças
André Pinto Rebouças, Brazilian engineer (Cachoeira, Bahia State 13 January 1838 – Funchal, Madeira Island 09 May 1898) ACHIEVEMENTS Suggested multiple docks (1863) Developed a kind of torpedo in time of war against Paraguay Published an incomplete monograph “Ensaio de um vocabulário technico da arte de construir e das sciencias accessorias, nas línguas franceza, ingleza e nacional” (1867-8), with which aided to elaborate an engineering’s technical terminology. These technique normalization anticipated that it occurred in Europe (1868-9) Invented a machine for tensile strength testing of cement mortar specimens (1866) Invented a process for manufacturing more economical and durable concrete bricks Adapted the port construction cofferdam for increased efficiency First to use groyne perpendicular to wharf line (1867) employing Barrett concept in Docas Dom Pedro II (Rio de Janeiro) Portos de Commercio – Novos estudos durante a viagem a Europa e aos Estados Unidos em 1872 e 1873. Rev Inst. Polytechn. Bras. (1875) SOME BIBLIOGRAPHY Estudo das leis do equilíbrio molecular dos sólidos (1880) With J. Rebouças. Ensaio de índice geral das madeiras do Brasil (1877-8) A secca nas províncias do norte (1877) O milho-forragem (1876) Acondicionamento da herva matte (1876) Arrazamento de rochas submarinas. Rev. Inst. Polytech. Brasileiro 4 (1874) Garantia de juros: estudos para sua applicação as emprezas de utilidade no Brazil (1874) With A. Rebouças. Estudos sobre os portos do mar (1872) Ensaio de um vocabulário dos termos technicos da arte de construir e das sciencias accessorias, mathematicas, astronomia, physica, botanica, mineralogia e zoologia nas línguas franceza, inglesa e nacional (1868-9) Motores hydraulicos (1862) His brother, Antonio Pereira Rebouças Filho, civil engineer (Cachoeira, Bahia State 13 June 1839 – Campinas, São Paulo State 26 May 1874) Responsible for 450 works, including bridges and overpasses SOME BIBLIOGRAPHY Vias férreas estreitas. Primeiros estudos (1871) Apontamentos sobre a via de comunicação do rio Madeira (1870)
Anders Fredrik Regnell
Anders Fredrik Regnell, Swedish-born Brazilian physician and naturalist (Stockholm 07 June 1807 – Caldas, Minas Gerais State 12 September 1884) Described the orchid species Brasiliorchis serotina 1881 with Barbosa Rodrigues HONORS Regnellidium Lindman 1904 (Pteridophyta) Neoregnellia Urban 1924 (Malvaceae)