Orestes Fiandra
Orestes Alfredo Fiandra Cuculic, Uruguayan cardiologist (Montevideo 04 August 1921 – Montevideo 22 April 2011) From Italian and Croatian descent Authored over 180 papers and 5 books With Roberto Rubio performed the first long-term pacemaker to be successfully implanted on a human in the world (1960) Developed self-anchoring electrode for permanent endocardial stimulation Suggested a new shape for endocardial electrode Developed an low threshold off electrode for cardiac pacemaker (1990) PATENTS Autofixation electrode Implantable artificial heart for human use (1994) With R. Suarez Antola an electrode for electric stimulation of living tissues HONOURS Member, New York Academy of Sciences
Olympio da Fonseca
Olympio Arthur Oliveira Ribeiro da Fonseca, Brazilian physician (Rio de Janeiro 07 May 1895 – Rio de Janeiro 19 April 1978) Brother of Brazilian zoologist Flávio da Fonseca ACHIEVEMENTS Performed studies in mycology, parasitology and tropical medicine Authored 150 works Showed that the pandemic flu was a virosis independently With A.M. Cunha & O. Magalhães. Estudos experimentais sobre a influenza pandemica. Mem. Inst. Oswaldo Cruz 10:174-91, 1918 First to demonstrate a sexual process in reproduction of blastomycosis-causating pathogenic yeasts in man (Debaryomyces sp.), 1922 Individualized and named chromoblastomycosis With Fernando Terra, Magarinos Torres & Area Leão. Novo typo de dermatite verrucosa, mycose por Acrotheca com associação de leishmaniosa. Bras.Med. 2:368-78, 1922. Developed the first specific skin test for paracoccidiodomycosis With A.E. Area Leão. Reaction cutanee specifique avec le filtrat de cellule du Coccidioides immitis. Comp. Rend. Seances Soc. Biol. 97:1796-7, 1927 First to note Aspergillus amstelodami causing black grains mycetoma of feet (1929) Novo método de terminação rápida do parto. Bol. Soc. Med. Cir. S. Paulo 4(12):333-5, 1922 DESCRIBED Protozoa Genera Chilomitus 1915 Enteromonas 1915 Globomonas 1918 Tetrachilomastix 1915 Described about 30 new Protozoan species Fungi Genera Glenosporopsis 1943 Piedraia 1928 with Area Leão Pochonia 1965 with Batista Teratoschaeta 1967 with Batista Diptera Subgenus Pseudoscione 1918 with Lutz & Souza Araújo HONORS Fonsecaia Pinto 1918 (Protozoa) Fonsecaea Negroni 1936 (Fungi) OTHERS Honoris Causa, Université de Paris (1952) Honorary President, VI (Rome) & VII (Stockholm) International Congress of Microbiology TRIVIA Set up the second in importance mycological collection in the world, Instituto Oswaldo Cruz (1920s)
Octavio Marcondes Ferraz
Octavio Marcondes Ferraz, Brazilian civil engineer (São Paulo 23 November 1896 – São Paulo 08 February 1990) With Domingos Marchetti, Gentil Norberto & André Jules Balança designed and built underground power plant Paulo Afonso I whose large scale rock excavation was one of the world’s great engineering feats of the 1950s (1949-55) Developed an original process of river shunt using cellular caissons in order to construct a hydroelectric plant (1955). This process permitted Brazilians create it without requering foreign specialists. First use in the world of floating iron beam coffin
Newton Freire-Maia
Newton Freire Maia, Brazilian human geneticist (Boa Esperança, Minas Gerais State 29 June 1918 – Curitiba 10 May 2003) Authored 474 works Recognized world authority in genetics of consanguineous marriages and ectodermal dysplasias With Marta Pinheiro created a worldwide used classification for ectodermal dysplasias With M. Pinheiro. Ectodermal dysplasias – some recollections and a classification. Birth Defects Orig. Art.Ser. 24:3-14, 1988. With Marta Pinheiro authored Ectodermal Dysplasias: a Clinical and Genetic Study (1984), the first book in the world about this theme NEW ECTODERMAL DYSPLASIAS With I. Cat, L.P. Marinoni, D.J. Giraldi, V.P. Furtado, R. Pasquini & H. Braga. Epidermolysis bullosa dystrophica, hypoplastic type, asociated with Pelger-Huet anomaly. Journal of Medical Genetics 4(4):302-3, 1967 With A. Freire-Maia & F.L. Freire-Maia. A newly recognized genetic syndrome of tetramelic deficiencies, ectodermal dysplasia, deformed ears and other abnormalities. American Journal of Medical Genetics 22(4):370-7, 1970. With I. Cat, V.L.V. Lopes, E.A. Chautard, F.A. Marçallo, I.J. Cavalli, R.F. Pilotto, M.C. Schetino & A.A. der Bedrossian. A new malformation syndrome. Lancet 1:840-1, 1970 With I. Cat, V.L.V. Lopes, E.A. Chautard, I.J. Cavalli, R.F. Pilotto & F.A. Marçallo. A síndrome de Maringá – Estudos clínicos, bioquímicos, dermatoglíficos e cromossômicos. Resumos da XXII Reunião Anual da Soc. Bras. Progr. Ciencia, p.130-1, 1970. With I. Cat & O. Costa. A clinical reappraisal of a newly recognized ectodermal dysplasia. American Journal of Medical Genetics 24:598-9, 1972 With V.A. Fortes, L.C. Pereira, J.M. Opitz, F.A. Marçallo & I.J. Cavalli. A syndrome of hypohidrotic ectodermal dysplasia with normal teeth, peculiar facies, pigmentary disturbances, psychomotor and growth retardation, bilateral nuclear cataract and other signs. Journal of Medical Genetics 12(3):308-10, 1975. With I. Cat & R.Rapone-Gaidzinski. An ectodermal dysplasia syndrome of alopecia, onychodysplasia, hypohidrosis, hyperkeratosis, deafness and other manifestations. Human Hereditary 27:127-33, 1977. With M.Pinheiro. Recessive anonychia totalis and dominant aplasia (or hypoplasia) of upper lateral incisors in the same kindred. Journ. Med. Genet. 17(2):45-8, 1979. With M. Pinheiro & C.C. Ortega. Recessive aplasia cutis congenita of the limbs. Journal of Medical Genetics 17(2):123-6, 1980. With M. Pinheiro & L.C. Pereira. A previouslu undescribed condition:tricho-odonto-onycho-dermal syndrome. A review of the tricho-odonto-onychial subgroup of ectodermal dysplasias. Brazilian Journal of Dermatology 105:371-82, 1981. With M. Pinheiro & L. C. Pereira. A previously undescribed condition. Tricho-odonto-onycho-dermal syndrome. A review of the tricho-odonto-onychial subgroup of ectodermal dysplasias. Br.J.Dermatol. 105:371-82, 1981. With A.F.P. Alves, P.A.B. Santos & E. Castelo Branco Neto. Na autosomal recessive ectodermal dysplasia syndrome of hypotrichosis, onychodysplasia, hyperkeratosis, kyphoscoliosis, cataract and other manifestations. Am.J.Med.Genet. 10:213-8, 1981. With D.V. Freire-Maia, C.E.P. Trindade, C.Y. Sughihara & J.M.Opitz. Nova síndrome malformativa acrorenal. Ciencia e Cultura 33:688, 1981. With M. Pinheiro & J.M. Opitz. The neurofaciodigitorenal (NFRD) syndrome. American Journal of Medical Genetics 11:329-36, 1982. With M. Pinheiro. Uma displasia ectodérmica pura devido a gene autossômico dominante. Ciência e cultura 34:764, 1982. With M. Pinheiro. Dermodontodysplasia: an eleven-member four generation pedigree with an apparently hitherto undescribed pure ectodermal dysplasia. Clin. Genet. 24:58-68, 1983. With M. Pinheiro & A.J. Roth. Trichoodontoonychial dysplasia – a new mesoectodermal dysplasia. Am.J.Med.Genet. 15:67-70, 1983. With M. Pinheiro, E.A. Chautard Freire-Maia, L.M.B. Araújo & B. Liberman. Aredyld: a syndrome combining na acrorenal Field defect, ectodermal dysplasia, lipoatrophic diabetes and other manifestations. Am.J.Med.Genet. 16:29-33, 1983. With M. Pinheiro & T.R. Goollop. Odontoonycho dysplasia with alopecia: a new pure ectodermal dysplasia with probable autosomal recessive inheritance. Am.J.Med.Genet. 20:197-202, 1985. With M. Pinheiro & A. Fernandes dos Santos. Trichoonychodysplasia with xeroderma, na apparently hitherto undescribed pure ectodermal dysplasia. Rev.Bras.Genet. 8(4):775-8, 1985. With M. Pinheiro, D.V. Freire-Maia, E. Miranda & O.G.Silva Filho. Trichodermodysplasia with dental alterations: an apparently new genetic ectodermal dysplasia of the tricho-odonto-onychial subgroup. Clin.Genet.29:332-6, 1986. With E.H. Tajara & M. Pinheiro. Pilodentoungular dysplasia with microcephaly, a new ectodermal dysplasia/malformation syndrome. Am.J.Med.Genet. 26:153-6, 1987. With R.B. Martínez, A.L. Monasterio & M. Pinheiro. Cleft lip, palate, oligodontia, syndactyly hair alterations, a new syndrome. Review of the conditions combining ectodermal dysplasia and cleft lip palate. Am.J.Med.Genet. 27:23-31, 1987. With L. Ceccato de Lima & M. Pinheiro. Oculotrichodysplasia (OTD), a new probably autosomal recessive condition. Journal of Medical Genetics 25:430-2, 1988. With M. Pinheiro. Displasia pêlo-unha (uma nova dysplasia ectodérmica pura): doze afetados em seis gerações de uma mesma família. Ver. Bras. Genet. 14 (Supp): 189, 1991. With M. Pinheiro. Hair-nail dysplasia. A new pure autosomal dominant ectodermal dysplasia. Clinical Genetics 41:296-8, 1992. With A. Montebelo Filho, A.R.S. Freire-Maia & M. Pinheiro. Odontoungueal dysplasia: an apparently new autosomal dominant ectodermal dysplasia. Braz. J. Genet. 19(3):162, 1996 (Suppl) With A.R.S. Freire & M. Pinheiro. Nova displasia ectodérmica do subgrupo odonto-onico-disidrótico. 48 Reunião Anual da Soc. Bras. Progr. Ciencia, 1996-7 METHODOLOGY A method to estimate mutational load With A. Freire-Maia. Novo método para a estimativa da carga mutacional. Boletim Soc. Bras. Genetica 6(1-2):23-24, 1964. A way to estimate mean number of deleterious genes in one person With a. Freire-Maia. Uma nova forma para a estimativa do número médio de gens deletérios por pessoa. Atas do Primeiro simpósio Sul-Americano de Genética, São Paulo, 264-5, 1961. With F.A. Marçallo. Coeficientes de inbreeding para gens ligados ao sexo. Bol. Soc. Bras. Genetica 2(2):14-6, 1960 Papers in top journals With M. Pinheiro. Identifying carriers for X-linked hypohydrotic ectodermal dysplasia. Lancet 2 (8044):936, 1977 With M.P. Pederneiras & E. Karam Jr. Umbilical tetanus in Brazil. Lancet 1 (7709):1134, 1971 With J.C. Brage, H. Abdala & N. Tartuce. Mental retardation: risks of recurrence. Lancet 1 (7661):1390, 1970 With L.G. Da Fonseca. Congenuital malformations of the limbs. Lancet 1 (7637):90-1, 1970 With J.B. Azevedo. Skeletal limb deficiencies. Lancet 2 (7581):1296, 1968 With E. Karam Jr. Phenylthiocarbamide and mental immaturity. Lancet 1 (7490):622, 1967 Pregnancy order and risk of abortion. Lancet 1 (7332):564-5, 1964 With A. Freire Maia A. Quelce Salgado. Parity effect on abortions. Lancet 1 (7284):774-5, 1963 With F.A. Marçallo. New recurrent series in inbreeding phenomena. Nature 189:421-2, 1961 With A. Quelce Salgado. Lethal mutations in Brazilian human populations. Nature 189:80, 1961 With A. Freire Maia. Estimate of the human load of mutations from heterogeneous consanguineous samples. Science 132 (3436):1317, 1960 EPONYMY Freire Maia syndrome (1970) Freire Maia-Pinheiro-Opitz syndrome
Newton Faller
Newton Faller, Brazilian electrical engineer and computer scientist (Rio de Janeiro 25 January 1947 – São Paulo 09 October 1996) Proposed the adaptive Huffman algorithms or Faller-Gallagher-Knuth algorithm, improved by Gallagher (1978) and Knuth (1985) An adaptive system for data compression. Record 7th Asilomar Conference on Circuits, Systems and Computers, pp.593-7, 1973 Headed the group that developed multiprocessor Pegasus and operating system Tropix, a real-time Unix-like operating system for PCs (1982-6) With P. Salembach & M.L. Anido. Design techniques used in the construction of the Pegasus 32X supermicrocomputer and the Plurix Operating System. Proc. Convención Inform. Latina (CIL-85), pp.178-95, 1985 With P. Salenbauch. Plurix: a multiprocessing Unix-like operating system. Proc. 2nd Workshop on Workstation Operating System, Washington, DC, USA, pp.29-36, 1989
Miguel Fernandez
Miguel Fernandez, Argentine biologist (Essen, Germany 25 September 1883 – Alta Gracia, Cordoba Province 29 April 1950) From Argentine father and German mother Performed contributions to histology, embriology and morphogenesis Demonstrated mesodermal origin of the vascular apparatus in Invertebrates Zur mikroskopische Anatomie des Blutgefässystems der Tunikaten Nebst Bemerkungen zur Phylogenie des Blutefassystems in allemeinen. Jenaische Zeitscher 39 (1904) Discovered and proved polyembryony in Mammalia Beitrage zur Embriologie der Gürteltiere. I. Zur Keimblatt erinversion und spezifischen polyembryonie der mulita (Tatusia hybrida Desm.). Morphol. Jahrbuch 39:302-33, 1909 HONORS Fernandezina Birabén 1951 (Arachnida) His wife, Kati Marcinowski de Fernandez, German / Argentine zoologist (Breslau 20 December 1877 – Alta Gracia, Cordoba Province 13 November 1955) First to establish mesenchymal origin of vascular apparatus in Vertebrata Zur Entstenhung der Gefassendothelien und des Blutes bei Amphibien. Jenaische Zeitscher 41 (1906) Authored Parasitisch und semiparasitisch an Pflanzen lebende Nematoden (1909), the most comprehensive treatise about plant parasite nematodes of his day and where she was the first to describe in detail the morphological differences between cysts and root-knot nematodes